Publications by authors named "Jean- Leon Thomas"

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Resolving the mysteries of brain clearance and immune surveillance.
Jonathan Kipnis, Helene Benveniste, Anne Eichmann, Jean-Leon Thomas, Daniel S Reich

Neuron· December 2025

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Fluid and Waste Clearance in Central Nervous System Health and Diseases.
Marie-Renee El Kamouh, Marie-Renee El Kamouh, Stéphanie Lenck, Stéphane Lehericy, Helene Benveniste, Jean-Léon Thomas

Neurodegener Dis· October 2025

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Murine Model of Cerebral Venous Outflow Occlusion Through Bilateral Ligation of Jugular Veins.
Marie-Renee El Kamouh, Myriam Spajer, Marie-Charlotte Bourrienne, Anne-Laure Joly Marolany, Ruchith Singhabahu, Jean-Léon Thomas

J Vis Exp· September 2025

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Rewiring of the glymphatic landscape in metabolic disorders.
Bandy Chen, David Meseguer, Stephanie Lenck, Jean-Leon Thomas, Marc Schneeberger

Trends Endocrinol Metab· August 2025

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Meningeal lymphatics-microglia axis regulates synaptic physiology.
Kyungdeok Kim, Daviti Abramishvili, Siling Du, Zachary Papadopoulos, Jay Cao, Jean-Leon Thomas

Cell· May 2025

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The glymphatic system as a nexus between obesity and neurological diseases.
Bandy Chen, Stephanie Lenck, Jean-Leon Thomas, Marc Schneeberger

Nat Rev Endocrinol· January 2025

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Monoclonal antibodies that block Roundabout 1 and 2 signaling target pathological ocular neovascularization through myeloid cells.
Luiz Henrique Geraldo, Yunling Xu, Gaspard Mouthon, Jessica Furtado, Felipe Saceanu Leser, Jean-Leon Thomas

Sci Transl Med· November 2024

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Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination.
Sofia P das Neves, Nickoleta Delivanoglou, Yingxue Ren, Chiara Starvaggi Cucuzza, Mateusz Makuch, Jean-Leon Thomas

Immunity· October 2024

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[Impact of meningeal lymphatic circulation on the response to ischemic stroke].
Jean-Léon Thomas, Ligia S B Boisserand, Marie-Rénée El Kamouh

Med Sci (Paris)· September 2024

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Meningeal lymphatic vessel dysfunction driven by CGRP signaling causes migraine-like pain in mice.
Jean-Leon Thomas, Emmanuelle Ad Schindler, Christopher Gottschalk

J Clin Invest· August 2024

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Elucidating a new path of CSF transport in the CNS.
Helene Benveniste, Jean-Leon Thomas

Lancet Neurol· June 2024

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Complementary and Inducible creER Mouse Models for Functional Evaluation of Endothelial Cell Subtypes in the Bone Marrow.
Michael G Poulos, Pradeep Ramalingam, Agatha Winiarski, Michael C Gutkin, Lizabeth Katsnelson, Jean-Leon Thomas

Stem Cell Rev Rep· May 2024

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Compartmentalized ocular lymphatic system mediates eye-brain immunity.
Xiangyun Yin, Sophia Zhang, Ju Hyun Lee, Huiping Dong, George Mourgkos, Jean-Leon Thomas

Nature· April 2024

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VEGF-C prophylaxis favors lymphatic drainage and modulates neuroinflammation in a stroke model.
Ligia Simoes Braga Boisserand, Luiz Henrique Geraldo, Jean Bouchart, Marie-Renee El Kamouh, Seyoung Lee, Jean-Leon Thomas

J Exp Med· April 2024

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Editorial Expression of Concern: The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system.
Xiaowei Lu, Ferdinand le Noble, Li Yuan, Quingjan Jiang, Benjamin de Lafarge, Jean- Léon Thomas

Nature· January 2024

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Intrathecal delivery of nanoparticle PARP inhibitor to the cerebrospinal fluid for the treatment of metastatic medulloblastoma.
Minsoo Khang, Ju Hyun Lee, Teresa Lee, Hee-Won Suh, Supum Lee, Jean-Leon Thomas

Sci Transl Med· November 2023

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Three-dimensional imaging of vascular development in the mouse epididymis.
Christelle Damon-Soubeyrand, Antonino Bongiovanni, Areski Chorfa, Chantal Goubely, Nelly Pirot, Jean-Leon Thomas

Elife· June 2023

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CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma.
Luiz Henrique Geraldo, Celina Garcia, Yunling Xu, Felipe Saceanu Leser, Izabella Grimaldi, Thomas Mathivet, Jean-Leon Thomas

Cell Mol Life Sci· June 2023

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VEGF-C promotes brain-derived fluid drainage, confers neuroprotection, and improves stroke outcomes.
Ligia Simoes Braga Boisserand, Jean Bouchart, Luiz Henrique Geraldo, Seyoung Lee, Basavaraju G Sanganahalli, Jean-Leon Thomas

bioRxiv· May 2023

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Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone.
Nafiisha Genet, Gael Genet, Nicholas W Chavkin, Umadevi Paila, Jennifer S Fang, Jean-Leon Thomas

Cell Rep· April 2023

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CSF-to-dura gateways.
Jean-Leon Thomas, Helene Benveniste

J Exp Med· February 2023

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Tribute to Klaus Eichmann, Editor-in-Chief of Cellular and Molecular Life Sciences.
Jean-Leon Thomas, Roberto Bruzzone, Assam El-Osta, Frank Claessens, Jean-Marie Ruysschaert

Cell Mol Life Sci· September 2022

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Conserved meningeal lymphatic drainage circuits in mice and humans.
Laurent Jacob, Jose de Brito Neto, Stephanie Lenck, Celine Corcy, Farhat Benbelkacem, Jean-Mickael Thomas, Jean-Leon Thomas

J Exp Med· August 2022

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Identification of growth hormone receptor as a relevant target for precision medicine in low-EGFR expressing glioblastoma.
Maïté Verreault, Irma Segoviano Vilchis, Shai Rosenberg, Nolwenn Lemaire, Charlotte Schmitt, Jean-Léon Thomas

Clin Transl Med· July 2022

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SLIT2/ROBO signaling in tumor-associated microglia and macrophages drives glioblastoma immunosuppression and vascular dysmorphia.
Luiz H Geraldo, Yunling Xu, Laurent Jacob, Laurence Pibouin-Fragner, Rohit Rao, Thomas Daubon, Thomas Viel, Jean-Leon Thomas, Thomas Mathivet

J Clin Invest· August 2021

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