Publications by authors named "Siling Du"

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Transcriptomics Guided Engineering of Exosome-Encapsulated Bifunctional Nanosheets Targeting the Immune-PI3K/Akt Axis for Osteoporosis Therapy.
Rongze Tang, Guanhong Liu, Congcong Wang, Minghao Chao, Guangyu Ma, Siling Du

Adv Sci (Weinh)· December 2025

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Mast cells regulate the brain-dura interface and CSF dynamics.
Tornike Mamuladze, Tiago H Zaninelli, Leon C D Smyth, Yue Wu, Daviti Abramishvili, Siling Du

Cell· October 2025

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ID2 secures cDC1 specification by antagonizing E proteins at a pleiotropic enhancer.
Feiya Ou, Tian-Tian Liu, Siling Du, Jing Chen, Alyssa R Koch

Res Sq· September 2025

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Correction: ADAPT-3D:accelerated deep adaptable processing of tissue for 3-dimensional fluorescence tissue imaging for research and clinical settings.
Daniel D Lee, Kevin A Telfer, Deanna L Davis, Leon C D Smyth, Rahul Ravindran, Siling Du

Sci Rep· September 2025

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ADAPT-3D:accelerated deep adaptable processing of tissue for 3-dimensional fluorescence tissue imaging for research and clinical settings.
Daniel D Lee, Kevin A Telfer, Deanna L Davis, Leon C D Smyth, Rahul Ravindran, Siling Du

Sci Rep· August 2025

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Mutations in the human CSF1R gene impact microglia's maintenance of brain white matter integrity.
Siling Du, Yingyue Zhou, Dian Li, Julia Lier, Marina Cella

Nat Immunol· July 2025

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Replacing microglia to treat a brain disease.
Siling Du, Jonathan Kipnis

Science· July 2025

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NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming.
Yanxia Rao, Siling Du, Baozhi Yang, Yuqing Wang, Yuxin Li, Xiangjuan Du

Neuron· June 2025

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Meningeal lymphatics-microglia axis regulates synaptic physiology.
Kyungdeok Kim, Daviti Abramishvili, Siling Du, Zachary Papadopoulos, Jay Cao

Cell· May 2025

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Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens.
Patrick Fernandes Rodrigues, Shitong Wu, Tihana Trsan, Santosh K Panda, José Luís Fachi, Siling Du

Cell· May 2025

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Beyond the brain: microglia-like cells regulate peripheral neuronal soma size.
Siling Du, Jonathan Kipnis

Cell Mol Immunol· May 2025

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Tracing LYVE1 peritoneal fluid macrophages unveils two paths to resident macrophage repopulation with differing reliance on monocytes.
Alexandre Gallerand, Jichang Han, Rachel L Mintz, Jing Chen, Daniel D Lee, Siling Du

bioRxiv· March 2025

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ADAPT-3D: Accelerated Deep Adaptable Processing of Tissue for 3-Dimensional Fluorescence Tissue Imaging for Research and Clinical Settings.
Daniel D Lee, Deanna L Davis, Leon C D Smyth, Kevin A Telfer, Rahul Ravindran, Siling Du

Res Sq· March 2025

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Functional classification of tauopathy strains reveals the role of protofilament core residues.
Jaime Vaquer-Alicea, Victor A Manon, Vaibhav Bommareddy, Peter Kunach, Ankit Gupta, Siling Du

Sci Adv· January 2025

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Optimization of the Irf8 +32-kb enhancer disrupts dendritic cell lineage segregation.
Feiya Ou, Tian-Tian Liu, Pritesh Desai, Stephen T Ferris, Sunkyung Kim, Siling Du

Nat Immunol· November 2024

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Engineered T cell therapy for central nervous system injury.
Wenqing Gao, Min Woo Kim, Taitea Dykstra, Siling Du, Pavle Boskovic

Nature· October 2024

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Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Identities from Microglia.
Siling Du, Antoine Drieu, Yumeng Cheng, Steffen E Storck, Justin Rustenhoven

bioRxiv· August 2024

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Identification of direct connections between the dura and the brain.
Leon C D Smyth, Di Xu, Serhat V Okar, Taitea Dykstra, Justin Rustenhoven, Siling Du

Nature· March 2024

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Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration.
Antoine Drieu, Siling Du, Michal Kipnis, Megan E Bosch, Jasmin Herz

Life Sci Alliance· November 2023

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Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage.
Justin Rustenhoven, Georgios Pavlou, Steffen E Storck, Taitea Dykstra, Siling Du

J Exp Med· July 2023

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A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.
Simone Brioschi, Julia A Belk, Vincent Peng, Martina Molgora, Patrick Fernandes Rodrigues, Siling Du

Immunity· May 2023

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Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
Linbo Chen, Qianping Zhang, Yuanyuan Meng, Tian Zhao, Chenglong Mu, Siling Du, Zhanqiang Du

EMBO Rep· April 2023

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Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid.
Antoine Drieu, Siling Du, Steffen E Storck, Justin Rustenhoven, Zachary Papadopoulos

Nature· November 2022

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Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice.
Tian Zhou, Yuxin Li, Xiaoyu Li, Fanzhuo Zeng, Yanxia Rao, Siling Du

Nat Commun· October 2022

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TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways.
Shoutang Wang, Raki Sudan, Vincent Peng, Yingyue Zhou, Siling Du

Cell· October 2022

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