Publications by authors named "Jeff L Staudinger"

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Pregnane X Receptor Signaling Pathway and Vitamin K: Molecular Mechanisms and Clinical Relevance in Human Health.
Jeff L Staudinger, Avina Mahroke, Gauri Patel, Cole Dattel, Sahana Reddy

Cells· April 2024

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The Interface between Cell Signaling Pathways and Pregnane X Receptor.
Robert S Rogers, Annemarie Parker, Phill D Vainer, Elijah Elliott, Dakota Sudbeck, Jeff L Staudinger

Cells· November 2021

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Associations between Pregnane X Receptor and Breast Cancer Growth and Progression.
Bradley A Creamer, Shelly N B Sloan, Jennifer F Dennis, Robert Rogers, Sidney Spencer, Jeff L Staudinger

Cells· October 2020

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Phosphorylation Modulates the Coregulatory Protein Exchange of the Nuclear Receptor Pregnane X Receptor.
Wenqi Cui, Xunan Shen, Emre Agbas, Brandon Tompkins, Hadley Cameron-Carter, Jeff L Staudinger

J Pharmacol Exp Ther· June 2020

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Clinical applications of small molecule inhibitors of Pregnane X receptor.
Jeff L Staudinger

Mol Cell Endocrinol· April 2019

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The Molecular Interface Between the SUMO and Ubiquitin Systems.
Jeff L Staudinger

Adv Exp Med Biol· September 2017

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A SUMO-acetyl switch in PXR biology.
Wenqi Cui, Mengxi Sun, Shupei Zhang, Xunan Shen, Nadezhda Galeva, Jeff L Staudinger

Biochim Biophys Acta· September 2016

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SUMOylation and Ubiquitylation Circuitry Controls Pregnane X Receptor Biology in Hepatocytes.
Wenqi Cui, Mengxi Sun, Nadezhda Galeva, Todd D Williams, Yoshiaki Azuma, Jeff L Staudinger

Drug Metab Dispos· September 2015

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Pregnane X receptor modulates the inflammatory response in primary cultures of hepatocytes.
Mengxi Sun, Wenqi Cui, Sarah K Woody, Jeff L Staudinger

Drug Metab Dispos· March 2015

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Nuclear-receptor-mediated regulation of drug- and bile-acid-transporter proteins in gut and liver.
Jeff L Staudinger, Sarah Woody, Mengxi Sun, Wenqi Cui

Drug Metab Rev· February 2013

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Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes.
Heather Hajovsky, Gang Hu, Yakov Koen, Diganta Sarma, Wenqi Cui, Jeff L Staudinger

Chem Res Toxicol· September 2012

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Post-translational modification of pregnane x receptor.
Jeff L Staudinger, Chenshu Xu, Arunima Biswas, Sridhar Mani

Pharmacol Res· July 2011

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Pregnane X receptor is SUMOylated to repress the inflammatory response.
Gang Hu, Chenshu Xu, Jeff L Staudinger

J Pharmacol Exp Ther· November 2010

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Nuclear receptor-mediated regulation of carboxylesterase expression and activity.
Jeff L Staudinger, Chenshu Xu, Yue J Cui, Curtis D Klaassen

Expert Opin Drug Metab Toxicol· March 2010

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A systematic analysis of predicted phosphorylation sites within the human pregnane X receptor protein.
Kristin Lichti-Kaiser, Dan Brobst, Chenshu Xu, Jeff L Staudinger

J Pharmacol Exp Ther· October 2009

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Regulation of tissue-specific carboxylesterase expression by pregnane x receptor and constitutive androstane receptor.
Chenshu Xu, Xinkun Wang, Jeff L Staudinger

Drug Metab Dispos· July 2009

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Activation of the JAK-STAT pathway is necessary for desensitization of 5-HT2A receptor-stimulated phospholipase C signalling by olanzapine, clozapine and MDL 100907.
Rakesh K Singh, Ying Dai, Jeff L Staudinger, Nancy A Muma

Int J Neuropsychopharmacol· June 2009

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Cyclic AMP-dependent protein kinase signaling modulates pregnane x receptor activity in a species-specific manner.
Kristin Lichti-Kaiser, Chenshu Xu, Jeff L Staudinger

J Biol Chem· March 2009

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The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes.
Kristin Lichti-Kaiser, Jeff L Staudinger

Drug Metab Dispos· August 2008

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Cell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.
Jeff L Staudinger, Kristin Lichti

Mol Pharm· April 2008

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Liver-enriched nuclear receptors: therapeutic opportunities.
Jeff L Staudinger

Mol Pharm· April 2008

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Pregnane X receptor and natural products: beyond drug-drug interactions.
Jeff L Staudinger, Xunshan Ding, Kristin Lichti

Expert Opin Drug Metab Toxicol· December 2006

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Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha.
Xunshan Ding, Kristin Lichti, Insook Kim, Frank J Gonzalez, Jeff L Staudinger

J Biol Chem· September 2006

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The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
Xunshan Ding, Kristin Lichti, Jeff L Staudinger

Toxicol Sci· June 2006

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The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter.
Xunshan Ding, Jeff L Staudinger

J Pharmacol Exp Ther· July 2005

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