Publications by authors named "Jeffrey A Meridew"

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Lung-targeted Lipid Nanoparticle Delivery of a Matricellular mRNA Promotes Fibrotic Lung Repair.
Kalpana R Betageri, Jeffrey A Meridew, Brian J Parrett, Rachel M Gilbert, Patrick A Link

Am J Respir Cell Mol Biol· October 2025

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Optimized Synthetic Flavonols Support Senescence Clearance and Lung Fibrosis Resolution.
Jeffrey A Meridew, John A Vu, Daniela Chow, Ana Maria Diaz Espinosa, Namita Saraf

ACS Pharmacol Transl Sci· September 2025

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Targeting the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprogramming and Inhibits Lung Fibrosis.
Jeongmin Hong, Tho X Pham, Jisu Lee, Ahmed A Raslan, Kristina Nicolas, Jeffrey A Meridew

Am J Respir Cell Mol Biol· June 2025

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Evaluation of the In Vivo Efficacy of the JAK Inhibitor AZD1480 in Uterine Leiomyomas Using a Patient-derived Xenograft Murine Model.
Michael F Neblett, Merrick T Ducharme, Jeffrey A Meridew, Andrew J Haak, Sylvie Girard

Reprod Sci· February 2025

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A Redox-Shifted Fibroblast Subpopulation Emerges in the Fibrotic Lung.
Patrick A Link, Jeffrey A Meridew, Nunzia Caporarello, Ashley Y Gao, Victor Peters

Am J Respir Cell Mol Biol· December 2024

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RNA-sequencing reveals differential fibroblast responses to bleomycin and pneumonectomy.
Jack H Wellmerling, Sara R Dresler, Jeffrey A Meridew, Kyoung M Choi, Daniel J Tschumperlin

Physiol Rep· July 2024

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Targeting CEBPA to restore cellular identity and tissue homeostasis in pulmonary fibrosis.
Qi Tan, Jack H Wellmerling, Shengren Song, Sara R Dresler, Jeffrey A Meridew

JCI Insight· July 2024

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Non-canonical IKB kinases regulate YAP/TAZ and pathological vascular remodeling behaviors in pulmonary artery smooth muscle cells.
Aja Aravamudhan, Paul B Dieffenbach, Kyoung Moo Choi, Patrick A Link, Jeffrey A Meridew

Physiol Rep· April 2024

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A redox-shifted fibroblast subpopulation emerges in the fibrotic lung.
Patrick A Link, Jeffrey A Meridew, Nunzia Caporarello, Ashley Y Gao, Victor Peters

bioRxiv· September 2023

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Author Correction: Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis.
Nunzia Caporarello, Jisu Lee, Tho X Pham, Dakota L Jones, Jiazhen Guan, Jeffrey A Meridew

Nat Commun· September 2022

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Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis.
Nunzia Caporarello, Jisu Lee, Tho X Pham, Dakota L Jones, Jiazhen Guan, Jeffrey A Meridew

Nat Commun· July 2022

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Transcriptional analysis of lung fibroblasts identifies PIM1 signaling as a driver of aging-associated persistent fibrosis.
Tho X Pham, Jisu Lee, Jiazhen Guan, Nunzia Caporarello, Jeffrey A Meridew

JCI Insight· March 2022

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ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation.
Dakota L Jones, Jeffrey A Meridew, Patrick A Link, Merrick T Ducharme, Katherine L Lydon

J Cell Biol· May 2021

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Spontaneous Lung Fibrosis Resolution Reveals Novel Antifibrotic Regulators.
Qi Tan, Patrick A Link, Jeffrey A Meridew, Tho X Pham, Nunzia Caporarello

Am J Respir Cell Mol Biol· April 2021

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Vascular dysfunction in aged mice contributes to persistent lung fibrosis.
Nunzia Caporarello, Jeffrey A Meridew, Aja Aravamudhan, Dakota L Jones, Susan A Austin

Aging Cell· August 2020

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TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation.
Aja Aravamudhan, Andrew J Haak, Kyoung Moo Choi, Jeffrey A Meridew, Nunzia Caporarello

Am J Physiol Lung Cell Mol Physiol· May 2020

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Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression.
Wei Liu, Jeffrey A Meridew, Aja Aravamudhan, Giovanni Ligresti, Daniel J Tschumperlin

Respir Res· December 2019

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Nascent Lung Organoids Reveal Epithelium- and Bone Morphogenetic Protein-mediated Suppression of Fibroblast Activation.
Qi Tan, Xiao Yin Ma, Wei Liu, Jeffrey A Meridew, Dakota L Jones

Am J Respir Cell Mol Biol· November 2019

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PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state.
Nunzia Caporarello, Jeffrey A Meridew, Dakota L Jones, Qi Tan, Andrew J Haak

Thorax· August 2019

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CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis.
Giovanni Ligresti, Nunzia Caporarello, Jeffrey A Meridew, Dakota L Jones, Qi Tan

JCI Insight· May 2019

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