Publications by authors named "Patrick A Link"

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Loss of lung mesenchymal identities in culture and a screening approach to identify restorative cues.
Ana M Diaz Espinosa, Jack H Wellmerling, Natalia Del Pilar Vanegas, Jhonny Rodriguez-Lopez, Kyoung M Choi, Patrick A Link

Am J Physiol Lung Cell Mol Physiol· December 2025

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Modulation of an aberrant basal cell program in human alveolar epithelial spheroids and lung slices subtitle: modulating aberrant basal cells in human cells and tissues.
Yong Li, Jack H Wellmerling, Lorena Rosas, Patrick A Link, Daniela Chow

Respir Res· December 2025

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Mechanobiology and Resolution of Lung Fibrosis.
Patrick A Link, Daniel J Tschumperlin

Annu Rev Physiol· November 2025

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Lung-targeted Lipid Nanoparticle Delivery of a Matricellular mRNA Promotes Fibrotic Lung Repair.
Kalpana R Betageri, Jeffrey A Meridew, Brian J Parrett, Rachel M Gilbert, Patrick A Link

Am J Respir Cell Mol Biol· October 2025

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Optimized Synthetic Flavonols Support Senescence Clearance and Lung Fibrosis Resolution.
Jeffrey A Meridew, John A Vu, Daniela Chow, Ana Maria Diaz Espinosa, Namita Saraf, Patrick A Link

ACS Pharmacol Transl Sci· September 2025

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Vascular protection by young circulating extracellular vesicles ameliorates aging-related pulmonary fibrosis.
Fiorenza Gianì, Benjamin B Roos, Patrick A Link, Bharath Somasundram, Sara R Dresler

Am J Physiol Cell Physiol· July 2025

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A Redox-Shifted Fibroblast Subpopulation Emerges in the Fibrotic Lung.
Patrick A Link, Jeffrey A Meridew, Nunzia Caporarello, Ashley Y Gao, Victor Peters

Am J Respir Cell Mol Biol· December 2024

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Non-canonical IKB kinases regulate YAP/TAZ and pathological vascular remodeling behaviors in pulmonary artery smooth muscle cells.
Aja Aravamudhan, Paul B Dieffenbach, Kyoung Moo Choi, Patrick A Link, Jeffrey A Meridew

Physiol Rep· April 2024

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Dopamine Receptor D1 Is Exempt from Transforming Growth Factor -Mediated Antifibrotic G Protein-Coupled Receptor Landscape Tampering in Lung Fibroblasts.
Ashley Y Gao, Ana M Diaz Espinosa, Ba Bao N Nguyen, Patrick A Link, Jeffrey Meridew

J Pharmacol Exp Ther· September 2023

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Using extracellular matrix derived from sugen-chronic hypoxia lung tissue to study pulmonary arterial hypertension.
Patrick A Link, Laszlo Farkas, Rebecca L Heise

Front Pharmacol· September 2023

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A redox-shifted fibroblast subpopulation emerges in the fibrotic lung.
Patrick A Link, Jeffrey A Meridew, Nunzia Caporarello, Ashley Y Gao, Victor Peters

bioRxiv· September 2023

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The matricellular protein CCN3 supports lung endothelial homeostasis and function.
Kalpana R Betageri, Patrick A Link, Andrew J Haak, Giovanni Ligresti, Daniel J Tschumperlin

Am J Physiol Lung Cell Mol Physiol· February 2023

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Dichotomous role of integrin-β5 in lung endothelial cells.
Neil Blanchard, Patrick A Link, Daniela Farkas, Brennan Harmon, Jaylen Hudson

Pulm Circ· October 2022

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Author Correction: Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis.
Nunzia Caporarello, Jisu Lee, Tho X Pham, Dakota L Jones, Jiazhen Guan, Patrick A Link

Nat Commun· September 2022

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Dopamine receptor signaling regulates fibrotic activation of retinal pigmented epithelial cells.
Ashley Y Gao, Patrick A Link, Sophie J Bakri, Andrew J Haak

Am J Physiol Cell Physiol· July 2022

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Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis.
Nunzia Caporarello, Jisu Lee, Tho X Pham, Dakota L Jones, Jiazhen Guan, Patrick A Link

Nat Commun· July 2022

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Combined control of the fibroblast contractile program by YAP and TAZ.
Patrick A Link, Kyoung Moo Choi, Ana M Diaz Espinosa, Dakota L Jones, Ashley Y Gao

Am J Physiol Lung Cell Mol Physiol· January 2022

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GPCR-mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7.
Kyoung Moo Choi, Andrew J Haak, Ana M Diaz Espinosa, Katherine A Cummins, Patrick A Link

J Cell Physiol· November 2021

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Cellular mitosis predicts vessel stability in a mechanochemical model of sprouting angiogenesis.
Patrick A Link, Rebecca L Heise, Seth H Weinberg

Biomech Model Mechanobiol· June 2021

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ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation.
Dakota L Jones, Jeffrey A Meridew, Patrick A Link, Merrick T Ducharme, Katherine L Lydon

J Cell Biol· May 2021

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Spontaneous Lung Fibrosis Resolution Reveals Novel Antifibrotic Regulators.
Qi Tan, Patrick A Link, Jeffrey A Meridew, Tho X Pham, Nunzia Caporarello

Am J Respir Cell Mol Biol· April 2021

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Dopamine D1 receptor stimulates cathepsin K-dependent degradation and resorption of collagen I in lung fibroblasts.
Ana M Diaz-Espinosa, Patrick A Link, Delphine Sicard, Ignasi Jorba, Daniel J Tschumperlin

J Cell Sci· December 2020

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Porcine Lung-Derived Extracellular Matrix Hydrogel Properties Are Dependent on Pepsin Digestion Time.
Robert A Pouliot, Bethany M Young, Patrick A Link, Heon E Park, Alison R Kahn

Tissue Eng Part C Methods· June 2020

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Electrosprayed extracellular matrix nanoparticles induce a pro-regenerative cell response.
Patrick A Link, Alexandria M Ritchie, Gabrielle M Cotman, Michael S Valentine, Bret S Dereski

J Tissue Eng Regen Med· December 2018

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Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture.
Patrick A Link, Robert A Pouliot, Nabil S Mikhaiel, Bethany M Young, Rebecca L Heise

J Vis Exp· January 2017

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