Publications by authors named "Jeffrey Barrett"

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Innovations and Best Practices for Therapeutic Development in Pediatric Rare Diseases: A Model-Informed Drug Development Perspective.
Rajesh Krishna, Satyendra Suryawanshi, Juliane Rascher, Sonja Hartmann, Bernard Sebastien, Jeffrey S Barrett

Clin Pharmacol Ther· December 2025

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Crowdsourcing Proposal Supporting Patient Engagement in Parkinson's Disease: A Digital Research Environment (DRE)-Enabled, Patient Swarm Approach to Develop QSP Models.
Jeffrey S Barrett, Benedetto Piccoli, Christopher Denaro, Stephan Schmidt, Valvanera Vozmediano, Kyle Barrett

J Clin Pharmacol· September 2025

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Consideration for Assessing Data/Models/Tools Expiration Supporting Drug Development and Clinical Decision Making.
Jeffrey S Barrett, Mark A Turner

Ther Innov Regul Sci· July 2025

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Unlocking the Mysteries of Rare Disease Drug Development: A Beginner's Guide for Clinical Pharmacologists.
Mariam A Ahmed, Bilal AbuAsal, Jeffrey S Barrett, Karim Azer, Yuen Yi Hon

Clin Transl Sci· April 2025

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Examining the role of common variants in rare neurodevelopmental conditions.
Qin Qin Huang, Emilie M Wigdor, Daniel S Malawsky, Patrick Campbell, Kaitlin E Samocha, Jeffrey C Barrett

Nature· December 2024

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Consideration of the Root Causes in Candidate Attrition During Oncology Drug Development.
Yin-Ming Kuo, Jeffrey S Barrett

Clin Pharmacol Drug Dev· September 2024

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A Modern Curriculum for Training Scientists in Model-Informed Drug Development: Progress Report on FDA Grant to Train Regulatory Scientists.
Jeffrey S Barrett, Klaus Romero, Craig Rayner, Marc Gastonguay, Goonaseelan Colin Pillai

Clin Pharmacol Ther· August 2024

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Artificial Intelligence Opportunities to Guide Precision Dosing Strategies.
Jeffrey S Barrett

J Pediatr Pharmacol Ther· August 2024

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Bringing platform trials closer to reality by enabling with digital research environment (DRE) connectivity.
Jeffrey S Barrett, Kara Lasater, Scott Russell, Susan McCune, Timothy M Miller

Contemp Clin Trials· July 2024

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Advancing the utilization of real-world data and real-world evidence in clinical pharmacology and translational research-Proceedings from the ASCPT 2023 preconference workshop.
Jing Liu, Karen Rowland-Yeo, Almut Winterstein, Simon Dagenais, Qi Liu, Jeffrey S Barrett

Clin Transl Sci· April 2024

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Training the next generation of pharmacometric modelers: a multisector perspective.
Peter L Bonate, Jeffrey S Barrett, Sihem Ait-Oudhia, Richard Brundage, Brian Corrigan

J Pharmacokinet Pharmacodyn· February 2024

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Correction to: Training the next generation of pharmacometric modelers: a multisector perspective.
Peter L Bonate, Jeffrey S Barrett, Sihem Ait-Oudhia, Richard Brundage, Brian Corrigan

J Pharmacokinet Pharmacodyn· February 2024

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The future of rare disease drug development: the rare disease cures accelerator data analytics platform (RDCA-DAP).
Jeffrey S Barrett, Alexandre Betourne, Ramona L Walls, Kara Lasater, Scott Russell

J Pharmacokinet Pharmacodyn· December 2023

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The Precompetitive Space for Drug or Vaccine Development: What Does It Look Like Now and What Could It Look Like in the Future?
Jeffrey S Barrett

J Pediatr Pharmacol Ther· October 2023

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An AI Approach to Generating MIDD Assets Across the Drug Development Continuum.
Jeffrey S Barrett, Rahul K Goyal, Jogarao Gobburu, Szczepan Baran, Jyotika Varshney

AAPS J· July 2023

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Supporting Prospective Pregnancy Trials via Modeling and Simulation: Lessons From the Past and Recommendations for the Future.
S Y Amy Cheung, Jeffrey S Barrett

J Clin Pharmacol· June 2023

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Opportunities for Systems Biology and Quantitative Systems Pharmacology to Address Knowledge Gaps for Drug Development in Pregnancy.
Jeffrey S Barrett, Karim Azer

J Clin Pharmacol· June 2023

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Digital Research Environment(DRE)-enabled Artificial Intelligence (AI) to facilitate early stage drug development.
Jeffrey S Barrett, Solmaz Eradat Oskoui, Scott Russell, Amanda Borens

Front Pharmacol· March 2023

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Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK Biobank.
Heli Julkunen, Anna Cichońska, Mika Tiainen, Harri Koskela, Kristian Nybo, Jeffrey C Barrett

Nat Commun· February 2023

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Natural History and Real-World Data in Rare Diseases: Applications, Limitations, and Future Perspectives.
Jing Liu, Jeffrey S Barrett, Efthimia T Leonardi, Lucy Lee, Satrajit Roychoudhury

J Clin Pharmacol· December 2022

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Context-specific emergence and growth of the SARS-CoV-2 Delta variant.
John T McCrone, Verity Hill, Sumali Bajaj, Rosario Evans Pena, Ben C Lambert, Jeffrey C Barrett

Nature· October 2022

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Landscape analysis for a neonatal disease progression model of bronchopulmonary dysplasia: Leveraging clinical trial experience and real-world data.
Jeffrey S Barrett, Megan Cala Pane, Timothy Knab, William Roddy, Jack Beusmans

Front Pharmacol· October 2022

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Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Aleksejs Sazonovs, Christine R Stevens, Guhan R Venkataraman, Kai Yuan, Brandon Avila, Jeffrey C Barrett

Nat Genet· September 2022

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Editorial: Insights in obstetric and pediatric pharmacology: 2021.
Jeffrey S Barrett

Front Pharmacol· September 2022

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The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK.
Verity Hill, Louis Du Plessis, Thomas P Peacock, Dinesh Aggarwal, Rachel Colquhoun, Jeffrey C Barrett

Virus Evol· August 2022

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