Publications by authors named "Jeffrey D Kittendorf"

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Substrate Trapping in Polyketide Synthase Thioesterase Domains: Structural Basis for Macrolactone Formation.
Tyler M McCullough, Vishakha Choudhary, David L Akey, Meredith A Skiba, Steffen M Bernard, Jeffrey D Kittendorf

ACS Catal· August 2024

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Substrate Trapping in Polyketide Synthase Thioesterase Domains: Structural Basis for Macrolactone Formation.
Tyler M McCullough, Vishakha Choudhary, David L Akey, Meredith A Skiba, Steffen M Bernard, Jeffrey D Kittendorf

bioRxiv· June 2024

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Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.
Douglas A Hansen, Christopher M Rath, Eli B Eisman, Alison R H Narayan, Jeffrey D Kittendorf

J Am Chem Soc· July 2013

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Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases.
Yi-Chen Chen, Allen F Brooks, DeeAnne M Goodenough-Lashua, Jeffrey D Kittendorf, Hollis D Showalter

Nucleic Acids Res· April 2011

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Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.
Jamie B Scaglione, David L Akey, Rachel Sullivan, Jeffrey D Kittendorf, Christopher M Rath

Angew Chem Int Ed Engl· August 2010

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Identification of the rate-determining step of tRNA-guanine transglycosylase from Escherichia coli.
George A Garcia, Stephanie M Chervin, Jeffrey D Kittendorf

Biochemistry· December 2009

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Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases.
Jonathan D Mortison, Jeffrey D Kittendorf, David H Sherman

J Am Chem Soc· November 2009

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The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis.
Jeffrey D Kittendorf, David H Sherman

Bioorg Med Chem· March 2009

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Probing the intermediacy of covalent RNA enzyme complexes in RNA modification enzymes.
Stephanie M Chervin, Jeffrey D Kittendorf, George A Garcia

Methods Enzymol· September 2007

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Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase.
Jeffrey D Kittendorf, Brian J Beck, Tonia J Buchholz, Wolfgang Seufert, David H Sherman

Chem Biol· August 2007

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Developing tools for engineering hybrid polyketide synthetic pathways.
Jeffrey D Kittendorf, David H Sherman

Curr Opin Biotechnol· December 2006

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Structural basis for macrolactonization by the pikromycin thioesterase.
David L Akey, Jeffrey D Kittendorf, John W Giraldes, Robert A Fecik, David H Sherman

Nat Chem Biol· October 2006

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Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.
John W Giraldes, David L Akey, Jeffrey D Kittendorf, David H Sherman, Janet L Smith

Nat Chem Biol· October 2006

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Transglycosylation: a mechanism for RNA modification (and editing?).
George A Garcia, Jeffrey D Kittendorf

Bioorg Chem· June 2005

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An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli.
Jeffrey D Kittendorf, Tanja Sgraja, Klaus Reuter, Gerhard Klebe, George A Garcia

J Biol Chem· October 2003

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