Publications by authors named "Jeffrey D Nanson"

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Employs a Rare Fatty Acid Desaturase for Niche-Specific Host Adaptation.
Felise G Adams, Saleh Alquethamy, Jack K Waters, Brynley J Davies, Ella Haracic, Jeffrey D Nanson

ACS Infect Dis· March 2025

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Signalling by co-operative higher-order assembly formation: linking evidence at molecular and cellular levels.
Bostjan Kobe, Jeffrey D Nanson, Mikayla Hoad, Antje Blumenthal, Yann Gambin

Biochem J· March 2025

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Structural basis for TIR domain-mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM.
Mohammad K Manik, Mengqi Pan, Le Xiao, Weixi Gu, Hyoyoung Kim, Jeffrey D Nanson

Proc Natl Acad Sci U S A· January 2025

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o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
Md Habibur Rahaman, Sara J Thygesen, Michael J Maxwell, Hyoyoung Kim, Prerna Mudai, Jeffrey D Nanson

J Enzyme Inhib Med Chem· December 2024

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Flow cytometric reporter assays provide robust functional analysis of signaling complexes.
Timothy W Muusse, Morris Y L Lee, Hyoyoung Kim, Marie-Odile Parat, Jeffrey D Nanson

J Biol Chem· December 2022

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Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
Mohammad K Manik, Yun Shi, Sulin Li, Mark A Zaydman, Neha Damaraju, Jeffrey D Nanson

Science· September 2022

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Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Yun Shi, Philip S Kerry, Jeffrey D Nanson, Todd Bosanac, Yo Sasaki

Mol Cell· May 2022

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The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs.
Liping Liu, Richard M Lucas, Jeffrey D Nanson, Yan Li, Jason Whitfield

J Biol Chem· May 2022

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Crystal structure of the Toll/interleukin-1 receptor (TIR) domain of IL-1R10 provides structural insights into TIR domain signalling.
Surekha Nimma, Weixi Gu, Mohammad K Manik, Thomas Ve, Jeffrey D Nanson

FEBS Lett· April 2022

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Structural Evolution of TIR-Domain Signalosomes.
Surekha Nimma, Weixi Gu, Natsumi Maruta, Yan Li, Mengqi Pan, Jeffrey D Nanson

Front Immunol· February 2022

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Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing.
Weixi Gu, Zhenyao Luo, Clemens Vonrhein, Xinying Jia, Thomas Ve, Jeffrey D Nanson

Acta Crystallogr F Struct Biol Commun· October 2021

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MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.
Max T B Clabbers, Susannah Holmes, Timothy W Muusse, Parimala R Vajjhala, Sara J Thygesen, Jeffrey D Nanson

Nat Commun· May 2021

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SARM1 is a metabolic sensor activated by an increased NMN/NAD ratio to trigger axon degeneration.
Matthew D Figley, Weixi Gu, Jeffrey D Nanson, Yun Shi, Yo Sasaki

Neuron· April 2021

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Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Bikshapathi Jagga, Megan Edwards, Miriam Pagin, Kylie M Wagstaff, David Aragão, Jeffrey D Nanson

Nat Commun· January 2021

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Structure, function, and regulation of thioesterases.
Crystall M D Swarbrick, Jeffrey D Nanson, Edward I Patterson, Jade K Forwood

Prog Lipid Res· July 2020

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Regulation of signaling by cooperative assembly formation in mammalian innate immunity signalosomes by molecular mimics.
Jeffrey D Nanson, Md Habibur Rahaman, Thomas Ve, Bostjan Kobe

Semin Cell Dev Biol· March 2020

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Structural characterization of β-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites.
Edward I Patterson, Jeffrey D Nanson, Jan Abendroth, Cassie Bryan, Banumathi Sankaran

Proteins· January 2020

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Structural characterization of a short-chain dehydrogenase/reductase from multi-drug resistant Acinetobacter baumannii.
Emily M Cross, David Aragão, Kate M Smith, Karli I Shaw, Jeffrey D Nanson

Biochem Biophys Res Commun· October 2019

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NAD cleavage activity by animal and plant TIR domains in cell death pathways.
Shane Horsefield, Hayden Burdett, Xiaoxiao Zhang, Mohammad K Manik, Yun Shi, Jeffrey D Nanson

Science· August 2019

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Death, TIR, and RHIM: Self-assembling domains involved in innate immunity and cell-death signaling.
Jeffrey D Nanson, Bostjan Kobe, Thomas Ve

J Leukoc Biol· February 2019

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Structural characterisation of the fatty acid biosynthesis enzyme FabF from the pathogen Listeria monocytogenes.
Tatiana P Soares da Costa, Jeffrey D Nanson, Jade K Forwood

Sci Rep· January 2017

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Structural Characterisation of FabG from Yersinia pestis, a Key Component of Bacterial Fatty Acid Synthesis.
Jeffrey D Nanson, Jade K Forwood

PLoS One· June 2016

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Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis.
Jeffrey D Nanson, Zainab Himiari, Crystall M D Swarbrick, Jade K Forwood

Sci Rep· October 2015

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Crystallization and preliminary X-ray diffraction analysis of FabG from Yersinia pestis.
Jeffrey David Nanson, Jade Kenneth Forwood

Acta Crystallogr F Struct Biol Commun· January 2014

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