Publications by authors named "Jeffrey Singer"

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Autism risk gene alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons.
Qiang-Qiang Xia, Anju Singh, Jing Wang, Zhong Xin Xuan, Jeffrey D Singer

Front Cell Neurosci· May 2024

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Effects of heterozygous deletion of autism-related gene Cullin-3 in mice.
Qiang-Qiang Xia, Angela K Walker, Chenghui Song, Jing Wang, Anju Singh, Jeffrey D Singer

PLoS One· July 2023

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Cullin 3-Mediated Regulation of Intracellular Iron Homeostasis Promotes Thymic Invariant NKT Cell Maturation.
Emily L Yarosz, Ajay Kumar, Jeffrey D Singer, Cheong-Hee Chang

Immunohorizons· March 2023

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A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts.
Carlene L Zindl, Steven J Witte, Vincent A Laufer, Min Gao, Zongliang Yue, Jeffrey R Singer

Immunity· March 2022

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Cul3 is required for normal development of the mammary gland.
Cristina M Cummings, Jeffrey D Singer

Cell Tissue Res· July 2021

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Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E.
Brittney Davidge, Katia Graziella de Oliveira Rebola, Larry N Agbor, Curt D Sigmund, Jeffrey D Singer

J Cell Sci· November 2019

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Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis.
Jeffrey R Singer, Emily G Blosser, Carlene L Zindl, Daniel J Silberger, Sean Conlan

Nat Med· November 2019

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Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension.
Larry N Agbor, Anand R Nair, Jing Wu, Ko-Ting Lu, Deborah R Davis, Jeffrey D Singer

JCI Insight· June 2019

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Cullin-3 dependent deregulation of ACTN1 represents a new pathogenic mechanism in nemaline myopathy.
Jordan Blondelle, Kavya Tallapaka, Jane T Seto, Majid Ghassemian, Madison Clark, Jeffrey D Singer

JCI Insight· April 2019

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Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis.
Turgay Saritas, Catherina A Cuevas, Mohammed Z Ferdaus, Christoph Kuppe, Rafael Kramann, Jeffrey D Singer

Sci Rep· March 2019

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Today's nonmedical opioid users are not yesterday's patients; implications of data indicating stable rates of nonmedical use and pain reliever use disorder.
Jeffrey A Singer, Jacob Z Sullum, Michael E Schatman

J Pain Res· February 2019

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Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.
Ryan J Cornelius, Chong Zhang, Kayla J Erspamer, Larry N Agbor, Curt D Sigmund, Jeffrey D Singer

Am J Physiol Renal Physiol· October 2018

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Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.
Daniel DiToro, Colleen J Winstead, Duy Pham, Steven Witte, Rakieb Andargachew, Jeffrey R Singer

Science· September 2018

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Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects.
Mohammed Z Ferdaus, Lauren N Miller, Larry N Agbor, Turgay Saritas, Jeffrey D Singer

JCI Insight· December 2017

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Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation.
Xinghui Li, Zhibin Zhang, Lupeng Li, Wei Gong, Audrey J Lazenby, Jeffrey D Singer

J Exp Med· April 2017

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Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.
Eitan Israeli, Dilyan I Dryanovski, Paul T Schumacker, Navdeep S Chandel, Jeffrey D Singer

Hum Mol Genet· June 2016

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Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension.
Chong Zhang, Nicholas P Meermeier, Andrew S Terker, Katharina I Blankenstein, Jeffrey D Singer

Biochem Biophys Res Commun· January 2016

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Daughter's Tolerance of Mom Matters in Mate Choice.
Jeffrey R Singer, Casey T Weaver

Cell· July 2015

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Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex.
Ivan Enghian Gladwyn-Ng, Shan Shan Li, Zhengdong Qu, John Michael Davis, Linh Ngo, Jeffrey Singer

Neural Dev· March 2015

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Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3.
James A McCormick, Chao-Ling Yang, Chong Zhang, Brittney Davidge, Katharina I Blankenstein, Jeffrey D Singer

J Clin Invest· November 2014

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Novel Cul3 binding proteins function to remodel E3 ligase complexes.
Wananit Wimuttisuk, Mark West, Brittney Davidge, Kebing Yu, Arthur Salomon, Jeffrey D Singer

BMC Cell Biol· July 2014

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A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation.
Rebecca Mathew, Ai-ping Mao, Andrew H Chiang, Clara Bertozzi-Villa, Jeffrey J Bunker, Jeffrey D Singer

J Exp Med· June 2014

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Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells.
Lester Lampert, Brittany Timonen, Sean Smith, Brittney Davidge, Haiyan Li, Jeffrey D Singer

Chem Commun (Camb)· February 2014

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Toward medical dystopia.
Jeffrey A Singer

J Trauma Acute Care Surg· September 2013

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BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.
Rebecca Mathew, Michael P Seiler, Seth T Scanlon, Ai-ping Mao, Michael G Constantinides, Jeffrey D Singer

Nature· November 2012

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