Publications by authors named "Jennifer Fishovitz"

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Tackling microbial resistance with 4H-chromen-4-one derivatives as a novel class of penicillin binding protein 2a inhibitors.
Menna-Allah W Shalaby, Nader S Abutaleb, Eman M E Dokla, Yehia Elgammal, Hsin-Wen Liang, Jennifer Fishovitz

Bioorg Med Chem· December 2025

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A Proteolytic Site-Directed Affinity Label to Inhibit the Human ATP-Dependent Protease Caseinolytic Complex XP.
Zhou Sha, Sujatha Chilakala, George Crabill, Iteen Cheng, Yan Xu, Jennifer Fishovitz

Chembiochem· July 2020

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A Selective Fluorogenic Peptide Substrate for the Human Mitochondrial ATP-Dependent Protease Complex ClpXP.
Zhou Sha, Jennifer Fishovitz, Susan Wang, Sujatha Chilakala, Yan Xu

Chembiochem· July 2020

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Cinnamonitrile Adjuvants Restore Susceptibility to β-Lactams against Methicillin-Resistant .
Enrico Speri, Choon Kim, Stefania De Benedetti, Yuanyuan Qian, Elena Lastochkin, Jennifer Fishovitz

ACS Med Chem Lett· August 2019

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Structure-activity relationship of the cinnamamide family of antibiotic potentiators for methicillin-resistant (MRSA).
Enrico Speri, Jennifer Fishovitz, Shahriar Mobashery

Medchemcomm· December 2018

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Utilization of Mechanistic Enzymology to Evaluate the Significance of ADP Binding to Human Lon Protease.
Jennifer Fishovitz, Zhou Sha, Sujatha Chilakala, Iteen Cheng, Yan Xu

Front Mol Biosci· July 2017

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From Genome to Proteome to Elucidation of Reactions for All Eleven Known Lytic Transglycosylases from Pseudomonas aeruginosa.
Mijoon Lee, Dusan Hesek, David A Dik, Jennifer Fishovitz, Elena Lastochkin

Angew Chem Int Ed Engl· March 2017

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Muropeptide Binding and the X-ray Structure of the Effector Domain of the Transcriptional Regulator AmpR of Pseudomonas aeruginosa.
David A Dik, Teresa Domínguez-Gil, Mijoon Lee, Dusan Hesek, Byungjin Byun, Jennifer Fishovitz

J Am Chem Soc· February 2017

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Phosphorylation of BlaR1 in Manifestation of Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus and Its Abrogation by Small Molecules.
Marc A Boudreau, Jennifer Fishovitz, Leticia I Llarrull, Qiaobin Xiao, Shahriar Mobashery

ACS Infect Dis· October 2015

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AAC(3)-XI, a new aminoglycoside 3-N-acetyltransferase from Corynebacterium striatum.
Marc Galimand, Jennifer Fishovitz, Thierry Lambert, Valérie Barbe, Jaroslav Zajicek

Antimicrob Agents Chemother· September 2015

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The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA).
Jennifer Fishovitz, Negin Taghizadeh, Jed F Fisher, Mayland Chang, Shahriar Mobashery

J Am Chem Soc· May 2015

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Penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.
Jennifer Fishovitz, Juan A Hermoso, Mayland Chang, Shahriar Mobashery

IUBMB Life· August 2014

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Disruption of allosteric response as an unprecedented mechanism of resistance to antibiotics.
Jennifer Fishovitz, Alzoray Rojas-Altuve, Lisandro H Otero, Matthew Dawley, Cesar Carrasco-López

J Am Chem Soc· July 2014

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How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function.
Lisandro H Otero, Alzoray Rojas-Altuve, Leticia I Llarrull, Cesar Carrasco-López, Malika Kumarasiri, Jennifer Fishovitz

Proc Natl Acad Sci U S A· October 2013

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Processive degradation of unstructured protein by Escherichia coli Lon occurs via the slow, sequential delivery of multiple scissile sites followed by rapid and synchronized peptide bond cleavage events.
Natalie Mikita, Iteen Cheng, Jennifer Fishovitz, Jonathan Huang, Irene Lee

Biochemistry· August 2013

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Identification of a region in the N-terminus of Escherichia coli Lon that affects ATPase, substrate translocation and proteolytic activity.
Iteen Cheng, Natalie Mikita, Jennifer Fishovitz, Hilary Frase, Patrick Wintrode

J Mol Biol· May 2012

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An amino acid position at crossroads of evolution of protein function: antibiotic sensor domain of BlaR1 protein from Staphylococcus aureus versus clasS D β-lactamases.
Malika Kumarasiri, Leticia I Llarrull, Oleg Borbulevych, Jennifer Fishovitz, Elena Lastochkin

J Biol Chem· March 2012

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Active-site-directed chemical tools for profiling mitochondrial Lon protease.
Jennifer Fishovitz, Min Li, Hilary Frase, Jason Hudak, Sandra Craig

ACS Chem Biol· August 2011

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N-Terminal peptidic boronic acids selectively inhibit human ClpXP.
Kenneth Knott, Jennifer Fishovitz, Steven B Thorpe, Irene Lee, Webster L Santos

Org Biomol Chem· August 2010

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Utilization of positional isotope exchange experiments to evaluate reversibility of ATP hydrolysis catalyzed by Escherichia coli Lon protease.
Jennifer Thomas, Jennifer Fishovitz, Irene Lee

Biochem Cell Biol· February 2010

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Utilization of synthetic peptides to evaluate the importance of substrate interaction at the proteolytic site of Escherichia coli Lon protease.
Jessica Patterson-Ward, Johnathan Tedesco, Jason Hudak, Jennifer Fishovitz, James Becker

Biochim Biophys Acta· September 2009

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