Publications by authors named "Patrick Wintrode"

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Characterization of cross-reactive, non-neutralizing monoclonal antibodies against a pandemic GII.4 norovirus variant.
Lauren A Ford-Siltz, Kentaro Tohma, Kyle Kihn, Joseph A Kendra, Daniel Deredge, Patrick Wintrode

Microbiol Spectr· October 2024

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The conformational landscape of a serpin N-terminal subdomain facilitates folding and in-cell quality control.
Upneet Kaur, Kyle C Kihn, Haiping Ke, Weiwei Kuo, Lila M Gierasch, Patrick L Wintrode

bioRxiv· April 2023

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Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin.
Kyle Kihn, Elisa Marchiori, Giovanni Spagnolli, Alberto Boldrini, Luca Terruzzi, Patrick L Wintrode

J Biol Chem· December 2022

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Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts.
Haarin Chun, James H Kurasawa, Philip Olivares, Ekaterina S Marakasova, Svetlana A Shestopal, Patrick L Wintrode

J Thromb Haemost· October 2022

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Interpreting Hydrogen-Deuterium Exchange Experiments with Molecular Simulations: Tutorials and Applications of the HDXer Ensemble Reweighting Software [Article v1.0].
Paul Suhwan Lee, Richard T Bradshaw, Fabrizio Marinelli, Kyle Kihn, Ally Smith, Patrick L Wintrode

Living J Comput Mol Sci· January 2022

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Modeling the native ensemble of PhuS using enhanced sampling MD and HDX-ensemble reweighting.
Kyle C Kihn, Tyree Wilson, Ally K Smith, Richard T Bradshaw, Patrick L Wintrode

Biophys J· December 2021

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A structure and function relationship study to identify the impact of the R721G mutation in the human mitochondrial lon protease.
Zhou Sha, Monica M Montano, Kristy Rochon, Jason A Mears, Daniel Deredge, Patrick Wintrode

Arch Biochem Biophys· October 2021

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Structure and dynamics of an α-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Erik H Klontz, Chao Li, Kyle Kihn, James K Fields, Dorothy Beckett, Patrick L Wintrode

Nat Commun· December 2020

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Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fcγ Receptor Binding.
Chiara Orlandi, Daniel Deredge, Krishanu Ray, Neelakshi Gohain, William Tolbert, Patrick Wintrode

Structure· May 2020

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Successes and challenges in simulating the folding of large proteins.
Anne Gershenson, Shachi Gosavi, Pietro Faccioli, Patrick L Wintrode

J Biol Chem· January 2020

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Monitoring dendrimer conformational transition using F and H O NMR.
Marc B Taraban, Daniel J Deredge, Margaret E Smith, Katharine T Briggs, Yu Li, Patrick L Wintrode

Magn Reson Chem· August 2019

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A temperature-dependent conformational shift in p38α MAPK substrate-binding region associated with changes in substrate phosphorylation profile.
Daniel Deredge, Patrick L Wintrode, Mohan E Tulapurkar, Ashish Nagarsekar, Yinghua Zhang

J Biol Chem· August 2019

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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.
Glenn R Masson, John E Burke, Natalie G Ahn, Ganesh S Anand, Christoph Borchers, Patrick L Wintrode

Nat Methods· July 2019

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Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb.
Jeffrey W Hudgens, Elyssia S Gallagher, Ioannis Karageorgos, Kyle W Anderson, James J Filliben, Patrick L Wintrode

Anal Chem· June 2019

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Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 °C and 25.4 °C for the Fab Fragment of NISTmAb.
Jeffrey W Hudgens, Elyssia S Gallagher, Ioannis Karageorgos, Kyle W Anderson, Richard Y-C Huang, Patrick L Wintrode

J Res Natl Inst Stand Technol· May 2019

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Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens.
Adam D Tomich, Erik H Klontz, Daniel Deredge, John P Barnard, Christi L McElheny, Patrick Wintrode

Antimicrob Agents Chemother· March 2019

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Molecular Basis of Broad Spectrum -Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2.
Erik H Klontz, Beatriz Trastoy, Daniel Deredge, James K Fields, Chao Li, Patrick L Wintrode

ACS Cent Sci· March 2019

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Conformational transition of a non-associative fluorinated amphiphile in aqueous solution. II. Conformational transition supramolecular assembly.
Marc B Taraban, Daniel J Deredge, Margaret E Smith, Katharine T Briggs, Yue Feng, Patrick L Wintrode

RSC Adv· January 2019

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The adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
Daniel A Bonsor, Qing Zhao, Barbara Schmidinger, Evelyn Weiss, Jingheng Wang, Patrick L Wintrode

EMBO J· July 2018

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All-Atom Simulations Reveal How Single-Point Mutations Promote Serpin Misfolding.
Fang Wang, Simone Orioli, Alan Ianeselli, Giovanni Spagnolli, Silvio A Beccara, Patrick L Wintrode

Biophys J· May 2018

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Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli.
Erik H Klontz, Adam D Tomich, Sebastian Günther, Justin A Lemkul, Daniel Deredge, Patrick L Wintrode

Antimicrob Agents Chemother· November 2017

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Remodeling KRAS.
Daniel J Deredge, Patrick L Wintrode

Structure· September 2017

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IL-1 Family Cytokines Use Distinct Molecular Mechanisms to Signal through Their Shared Co-receptor.
Sebastian Günther, Daniel Deredge, Amanda L Bowers, Alessandra Luchini, Daniel A Bonsor, Patrick L Wintrode

Immunity· September 2017

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Common coding variant in increases the risk for large artery stroke.
Rainer Malik, Therese Dau, Maria Gonik, Anirudh Sivakumar, Daniel J Deredge, Patrick L Wintrode

Proc Natl Acad Sci U S A· April 2017

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Ligand-induced allostery in the interaction of the heme binding protein with heme oxygenase.
Daniel J Deredge, Weiliang Huang, Colleen Hui, Hirotoshi Matsumura, Zhi Yue, Patrick L Wintrode

Proc Natl Acad Sci U S A· March 2017

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