Publications by authors named "Jennifer Munkert"

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Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells.
Cecilia L D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert

Adv Healthc Mater· December 2025

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Progestogens and androgens influence root morphology of angiosperms in a brassinosteroid-independent manner.
Karl Ludwig Körber, Sudip Paul, Jana Oklestkova, Emanuel Barth, Felix Feistel, Jennifer Munkert

Plant J· September 2025

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Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome.
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch

Small· July 2025

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A dataset for machine learning-based QSAR models establishment to screen beta-lactamase inhibitors using the FARM -BIOMOL chemical library.
Thanet Pitakbut, Jennifer Munkert, Wenhui Xi, Yanjie Wei, Gregor Fuhrmann

BMC Res Notes· March 2025

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Addressing the Evolution of Cardenolide Formation in Iridoid-Synthesizing Plants: Site-Directed Mutagenesis of PRISEs (Progesterone-5β-Reductase/Iridoid Synthase-like Enzymes) of Plantago Species.
Maja Dorfner, Jan Klein, Katharina Senkleiter, Harald Lanig, Wolfgang Kreis, Jennifer Munkert

Molecules· December 2024

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Utilizing machine learning-based QSAR model to overcome standalone consensus docking limitation in beta-lactamase inhibitors screening: a proof-of-concept study.
Thanet Pitakbut, Jennifer Munkert, Wenhui Xi, Yanjie Wei, Gregor Fuhrmann

BMC Chem· December 2024

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Overexpression and RNAi-mediated Knockdown of Two 3β-hydroxy-Δ5-steroid dehydrogenase Genes in Digitalis lanata Shoot Cultures Reveal Their Role in Cardenolide Biosynthesis.
Tim Leykauf, Jan Klein, Mona Ernst, Maja Dorfner, Anastasiia Ignatova, Jennifer Munkert

Planta Med· July 2023

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Effects of Lipophilicity and Structural Features on the Antiherpes Activity of Digitalis Cardenolides and Derivatives.
Rodrigo Maia de Pádua, Jadel Müller Kratz, Jennifer Munkert, Jéssica Wildgrube Bertol, Caroline Rigotto

Chem Biodivers· October 2022

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Knockout of  , Encoding a PRISE (Progesterone 5β-Reductase/Iridoid Synthase-Like Enzyme), Leads to Metabolic Changes in Response to Exogenous Methyl Vinyl Ketone (MVK).
Jan Klein, Mona Ernst, Alexander Christmann, Marina Tropper, Tim Leykauf, Jennifer Munkert

Metabolites· December 2021

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RNAi-mediated gene knockdown of progesterone 5β-reductases in Digitalis lanata reduces 5β-cardenolide content.
Jan Klein, Elisa Horn, Mona Ernst, Tim Leykauf, Tamara Leupold, Jennifer Munkert

Plant Cell Rep· September 2021

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21-Hydroxypregnane 21-O-malonylation, a crucial step in cardenolide biosynthesis, can be achieved by substrate-promiscuous BAHD-type phenolic glucoside malonyltransferases from Arabidopsis thaliana and homolog proteins from Digitalis lanata.
Marina Tropper, Stephanie Höhn, Laura-Sophie Wolf, Julia Fritsch, Nina Kastner-Detter, Jennifer Munkert

Phytochemistry· July 2021

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Cytotoxicity of glucoevatromonoside alone and in combination with chemotherapy drugs and their effects on Na,K-ATPase and ion channels on lung cancer cells.
Naira Fernanda Zanchett Schneider, Danusa Menegaz, Andre Luiz Andreotti Dagostin, Lara Persich, Sayonarah C Rocha, Jennifer Munkert

Mol Cell Biochem· April 2021

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In vitro and in vivo antileishmanial activity of β-acetyl-digitoxin, a cardenolide of Digitalis lanata potentially useful to treat visceral leishmaniasis.
Camila S Freitas, Daniela P Lage, João A Oliveira-da-Silva, Rafaella R Costa, Débora V C Mendonça, Jennifer Munkert

Parasite· April 2021

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Digitoxigenin presents an effective and selective antileishmanial action against Leishmania infantum and is a potential therapeutic agent for visceral leishmaniasis.
Camila S Freitas, João A Oliveira-da-Silva, Daniela P Lage, Rafaella R Costa, Débora V C Mendonça, Jennifer Munkert

Parasitol Res· January 2021

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Semisynthetic Cardenolides Acting as Antiviral Inhibitors of Influenza A Virus Replication by Preventing Polymerase Complex Formation.
Laurita Boff, André Schreiber, Aline da Rocha Matos, Juliana Del Sarto, Linda Brunotte, Jennifer Munkert

Molecules· October 2020

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Investigation of the cytotoxic activity of two novel digitoxigenin analogues on H460 lung cancer cells.
Laurita Boff, Lara Persich, Paula Brambila, Flaviano Melo Ottoni, Jennifer Munkert

Anticancer Drugs· June 2020

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Elucidation of the mechanism of anti-herpes action of two novel semisynthetic cardenolide derivatives.
Laurita Boff, Naira Fernanda Zanchett Schneider, Jennifer Munkert, Flaviano Melo Ottoni, Gabriela Silva Ramos

Arch Virol· June 2020

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Biosynthetic approach to combine the first steps of cardenolide formation in Saccharomyces cerevisiae.
Christoph Rieck, Daniel Geiger, Jennifer Munkert, Katrin Messerschmidt, Jan Petersen

Microbiologyopen· December 2019

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New Tc-Labeled Digitoxigenin Derivative for Cancer Cell Identification.
Jennifer Munkert, Eliza R Gomes, Lucas L Marostica, Betânia B Cota, Cristina L M Lopes

ACS Omega· December 2019

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Potential anti-herpes and cytotoxic action of novel semisynthetic digitoxigenin-derivatives.
Laurita Boff, Jennifer Munkert, Flaviano Melo Ottoni, Naira Fernanda Zanchett Schneider, Gabriela Silva Ramos

Eur J Med Chem· April 2019

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Exploiting enzyme promiscuity to shape plant specialized metabolism.
Wolfgang Kreis, Jennifer Munkert

J Exp Bot· March 2019

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PRISEs (progesterone 5β-reductase and/or iridoid synthase-like 1,4-enone reductases): Catalytic and substrate promiscuity allows for realization of multiple pathways in plant metabolism.
Karin Schmidt, Jan Petersen, Jennifer Munkert, Claudia Egerer-Sieber, Michael Hornig

Phytochemistry· December 2018

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Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na/K-ATPase inhibition.
Izabella Thaís Silva, Jennifer Munkert, Elke Nolte, Naira Fernanda Zanchett Schneider, Sayonarah Carvalho Rocha

Biomed Pharmacother· November 2018

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Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.
Naira F Z Schneider, Claudia Cerella, Jin-Young Lee, Aloran Mazumder, Kyung Rok Kim, Jennifer Munkert

Front Pharmacol· March 2018

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Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase.
Naira Fernanda Zanchett Schneider, Lara Persich, Sayonarah C Rocha, Ana Carolina Pacheco Ramos, Vanessa Faria Cortes, Jennifer Munkert

Biomed Pharmacother· January 2018

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