Publications by authors named "Jens F Halling"

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CagriSema drives weight loss in rats by reducing energy intake and preserving energy expenditure.
Julie Mie Jacobsen, Jens Frey Halling, Ida Blom, Jaime Moreno Martinez, Bjørn Hald

Nat Metab· July 2025

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Skeletal muscle from TBC1D4 p.Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise.
Jonas M Kristensen, Rasmus Kjøbsted, Trine J Larsen, Christian S Carl, Janne R Hingst, Jens F Halling

Nat Metab· December 2024

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The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms.
Tang Cam Phung Pham, Steffen Henning Raun, Essi Havula, Carlos Henriquez-Olguín, Diana Rubalcava-Gracia, Jens Frey Halling

Nat Commun· November 2024

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Muscle PGC-1α modulates hepatic mitophagy regulation during aging.
Natascha Masselkhi Christensen, Stine Ringholm, Bjørg Thiellesen Buch, Anders Gudiksen, Jens Frey Halling

Exp Gerontol· February 2023

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Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomized, clinical trials.
Nanna S Pilmark, Laura Oberholzer, Jens F Halling, Jonas M Kristensen, Christina P Bønding

Appl Physiol Nutr Metab· March 2022

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Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise.
Janne R Hingst, Rasmus Kjøbsted, Jesper B Birk, Nicolas O Jørgensen, Magnus R Larsen, Jens F Halling

Mol Metab· October 2020

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PGC-1α-mediated regulation of mitochondrial function and physiological implications.
Jens Frey Halling, Henriette Pilegaard

Appl Physiol Nutr Metab· September 2020

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Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner.
Bjørg Thiellesen Buch, Jens Frey Halling, Stine Ringholm, Anders Gudiksen, Rasmus Kjøbsted

FASEB J· June 2020

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PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training.
Jens Frey Halling, Henrik Jessen, Jacob Nøhr-Meldgaard, Bjørg Thiellesen Buch, Natascha Masselkhi Christensen

Am J Physiol Endocrinol Metab· September 2019

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Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle.
M Reza Sailani, Jens Frey Halling, Henrik Devitt Møller, Hayan Lee, Peter Plomgaard

Sci Rep· March 2019

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Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers.
Thomas Kjeld, Nis Stride, Anders Gudiksen, Egon Godthaab Hansen, Henrik Christian Arendrup, Jens Frey Halling

PLoS One· February 2019

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Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training.
Maja Munk Dethlefsen, Jens Frey Halling, Henrik D Møller, Peter Plomgaard, Birgitte Regenberg

Exp Gerontol· October 2018

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The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice.
Nina Brandt, Dorota Kotowska, Caroline M Kristensen, Jesper Olesen, Ditte O Lützhøft, Jens F Halling

Physiol Rep· October 2018

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Circular DNA elements of chromosomal origin are common in healthy human somatic tissue.
Henrik Devitt Møller, Marghoob Mohiyuddin, Iñigo Prada-Luengo, M Reza Sailani, Jens Frey Halling

Nat Commun· March 2018

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Exercise training protects against aging-induced mitochondrial fragmentation in mouse skeletal muscle in a PGC-1α dependent manner.
Jens Frey Halling, Stine Ringholm, Jesper Olesen, Clara Prats, Henriette Pilegaard

Exp Gerontol· October 2017

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Autophagy-Dependent Beneficial Effects of Exercise.
Jens Frey Halling, Henriette Pilegaard

Cold Spring Harb Perspect Med· August 2017

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PGC-1α promotes exercise-induced autophagy in mouse skeletal muscle.
Jens F Halling, Stine Ringholm, Maja M Nielsen, Peter Overby, Henriette Pilegaard

Physiol Rep· February 2016

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Exercise-induced AMPK and pyruvate dehydrogenase regulation is maintained during short-term low-grade inflammation.
Rasmus Sjørup Biensø, Jesper Olesen, Line van Hauen, Simon Meinertz, Jens Frey Halling

Pflugers Arch· February 2015

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Role of PGC-1α in exercise training- and resveratrol-induced prevention of age-associated inflammation.
Jesper Olesen, Stine Ringholm, Maja M Nielsen, Christina T Brandt, Jesper T Pedersen, Jens F Halling

Exp Gerontol· November 2013

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Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1α.
Stine Ringholm, Jesper Olesen, Jesper Thorhauge Pedersen, Christina Tingbjerg Brandt, Jens Frey Halling

Exp Gerontol· November 2013

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