Publications by authors named "Jens Humrich"

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Transition from psoriasis to psoriatic arthritis is characterized by distinct alterations in peripheral blood Tc17, Th17 and CD4+ TEM cells.
Hanna Graßhoff, Sara Comdühr, Henry Nording, Jacob von Esebeck, Philine Letz, Jens Y Humrich

Arthritis Rheumatol· September 2025

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Advancing research on regulatory autoantibodies targeting GPCRs: Insights from the 5th international symposium.
Otavio Cabral-Marques, Lena F Schimke, Guido Moll, Igor Salerno Filgueiras, Adriel Leal Nóbile, Jens Y Humrich

Autoimmun Rev· August 2025

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Antibodies targeting G protein-coupled receptors in systemic sclerosis: comment on the article by van Oostveen et al.
Reza Akbarzadeh, Alexander Hackel, Jens Y Humrich, Gabriela Riemekasten, Kristina Kusche-Vihrog

Arthritis Rheumatol· July 2025

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Combination therapy of rituximab and mycophenolate in patients with systemic sclerosis and primary cardiac involvement refractory to cyclophosphamide: a retrospective exploratory analysis of 10 cases.
El-Baraa Adjailia, Hanna Grasshoff, Susanne Schinke, Konstantinos Fourlakis, Sebastian T Jendrek, Jens Y Humrich

RMD Open· June 2025

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Editorial: Innate immune dysregulation: a driving force of autoimmunity and chronic inflammation.
Reza Akbarzadeh, Jens Y Humrich, Tamás Németh, Kyle T Amber

Front Immunol· June 2025

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Metabolomic signature identifies HDL and apolipoproteins as potential biomarker for systemic sclerosis with interstitial lung disease.
Sebastian T Jendrek, Franziska Schmelter, Susanne Schinke, Alexander Hackel, Hanna Graßhoff, Jens Y Humrich

Respir Med· November 2024

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Autoantibodies against the chemokine receptor 3 predict cardiovascular risk.
Felix S Müller, Zouhair Aherrahrou, Hanna Grasshoff, Marc W Heidorn, Jens Y Humrich

Eur Heart J· December 2023

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Regulatory T cells inhibit autoantigen-specific CD4 T cell responses in lupus-prone NZB/W F1 mice.
Stefan Rosenberger, Reinmar Undeutsch, Reza Akbarzadeh, Justus Ohmes, Philipp Enghard, Jens Y Humrich

Front Immunol· December 2023

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When natural antibodies become pathogenic: autoantibodies targeted against G protein-coupled receptors in the pathogenesis of systemic sclerosis.
Reza Akbarzadeh, Antje Müller, Jens Y Humrich, Gabriela Riemekasten

Front Immunol· June 2023

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Low-dose interleukin-2 therapy: a promising targeted therapeutic approach for systemic lupus erythematosus.
Reza Akbarzadeh, Gabriela Riemekasten, Jens Y Humrich

Curr Opin Rheumatol· March 2023

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Autoimmune pre-disease.
Katja Bieber, Jennifer E Hundt, Xinhua Yu, Marc Ehlers, Frank Petersen, Jens Y Humrich

Autoimmun Rev· February 2023

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Low-dose interleukin-2 therapy in active systemic lupus erythematosus (LUPIL-2): a multicentre, double-blind, randomised and placebo-controlled phase II trial.
Jens Y Humrich, Patrice Cacoub, Michelle Rosenzwajg, Fabien Pitoiset, Hang Phuong Pham

Ann Rheum Dis· December 2022

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Dysregulation and chronicity of pathogenic T cell responses in the pre-diseased stage of lupus.
Justus Ohmes, Sara Comdühr, Reza Akbarzadeh, Gabriela Riemekasten, Jens Y Humrich

Front Immunol· November 2022

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Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19.
Florian Tran, Danielle M M Harris, Alena Scharmacher, Hanna Graßhoff, Kristina Sterner, Jens Y Humrich

ERJ Open Res· October 2022

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Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
Otavio Cabral-Marques, Gilad Halpert, Lena F Schimke, Yuri Ostrinski, Aristo Vojdani, Jens Y Humrich

Nat Commun· March 2022

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A patient with acute-onset hemorrhagic necroses and bullae of the legs.
Hanna Graßhoff, Verena-Wilbeth Sailer, Jens Humrich, Gabriela Riemekasten, Peter Lamprecht

Rheumatology (Oxford)· November 2021

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Low-Dose IL-2 Therapy in Autoimmune and Rheumatic Diseases.
Hanna Graßhoff, Sara Comdühr, Luisa R Monne, Antje Müller, Peter Lamprecht, Jens Y Humrich

Front Immunol· October 2021

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Phenotyping of Adaptive Immune Responses in Inflammatory Diseases.
Jens Y Humrich, Joana P Bernardes, Ralf J Ludwig, David Klatzmann, Alexander Scheffold

Front Immunol· June 2021

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Nuclear antigen-reactive CD4 T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys.
Dimas Abdirama, Sebastian Tesch, Anna-Sophie Grießbach, Caroline von Spee-Mayer, Jens Y Humrich

Kidney Int· January 2021

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Extracorporeal membrane oxygenation in ANCA-associated vasculitis.
Sabrina Arnold, Maria Deja, Martin Nitschke, Sabine Bohnet, Sönke Wallis, Jens Y Humrich

Autoimmun Rev· January 2021

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Identification and characterization of antigen-specific CD4 T cells targeting renally expressed antigens in human lupus nephritis with two independent methods.
Sebastian Tesch, Dimas Abdirama, Anna-Sophie Grießbach, Hannah Antonia Brand, Nina Goerlich, Jens Y Humrich

Sci Rep· December 2020

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Low-dose IL-2 for patients with systemic lupus erythematosus - Authors' reply.
Jens Y Humrich, Gabriela Riemekasten

Lancet Rheumatol· December 2019

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IL-2 Therapy Diminishes Renal Inflammation and the Activity of Kidney-Infiltrating CD4+ T Cells in Murine Lupus Nephritis.
Angelika Rose, Caroline von Spee-Mayer, Lutz Kloke, Kaiyin Wu, Anja Kühl, Jens Y Humrich

Cells· October 2019

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Low-dose interleukin-2 therapy in refractory systemic lupus erythematosus: an investigator-initiated, single-centre phase 1 and 2a clinical trial.
Jens Y Humrich, Caroline von Spee-Mayer, Elise Siegert, Martina Bertolo, Angelika Rose

Lancet Rheumatol· September 2019

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Evaluation of retinal microvascular perfusion in systemic sclerosis: a case-control study.
Matthias Rothe, Felix Rommel, Sebastian Klapa, Jens Y Humrich, Relana Nieberding

Ann Rheum Dis· June 2019

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