Publications by authors named "Jerald C Sadoff"

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Safety and Immunogenicity of Adenovirus 35 Tuberculosis Vaccine Candidate in Adults with Active or Previous Tuberculosis. A Randomized Trial.
Richard N van Zyl-Smit, Aliasgar Esmail, Mary E Bateman, Rodney Dawson, Jonathan Goldin, Jerald C Sadoff

Am J Respir Crit Care Med· May 2017

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A nonhuman primate toxicology and immunogenicity study evaluating aerosol delivery of AERAS-402/Ad35 vaccine: Evidence for transient t cell responses in peripheral blood and robust sustained responses in the lungs.
David A Hokey, Robert Wachholder, Patricia A Darrah, Diane L Bolton, Dan H Barouch, Jerald C Sadoff

Hum Vaccin Immunother· July 2015

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The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses.
Benjamin M N Kagina, Michele D Tameris, Hennie Geldenhuys, Mark Hatherill, Brian Abel, Jerald C Sadoff

Vaccine· October 2014

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Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge.
Patricia A Darrah, Diane L Bolton, Andrew A Lackner, Deepak Kaushal, Pyone Pyone Aye, Jerald C Sadoff

J Immunol· August 2014

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Induction and regulation of T-cell immunity by the novel tuberculosis vaccine M72/AS01 in South African adults.
Cheryl L Day, Michele Tameris, Nazma Mansoor, Michele van Rooyen, Marwou de Kock, Jerald C Sadoff

Am J Respir Crit Care Med· August 2013

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Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys.
Dan H Barouch, Jinyan Liu, Hualin Li, Lori F Maxfield, Peter Abbink, Jerald C Sadoff

Nature· January 2012

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Optimizing HIV-1-specific CD8+ T-cell induction by recombinant BCG in prime-boost regimens with heterologous viral vectors.
Richard Hopkins, Anne Bridgeman, Charles Bourne, Alice Mbewe-Mvula, Jerald C Sadoff

Eur J Immunol· December 2011

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Genetic immunization in the lung induces potent local and systemic immune responses.
Kaimei Song, Diane L Bolton, Chih-Jen Wei, Robert L Wilson, Jeremy V Camp, Jerald C Sadoff

Proc Natl Acad Sci U S A· December 2010

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Safety and immunogenicity of novel recombinant BCG and modified vaccinia virus Ankara vaccines in neonate rhesus macaques.
Maximillian Rosario, John Fulkerson, Shamit Soneji, Joe Parker, Eung-Jun Im, Jerald C Sadoff

J Virol· August 2010

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The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults.
Brian Abel, Michele Tameris, Nazma Mansoor, Sebastian Gelderbloem, Jane Hughes, Jerald C Sadoff

Am J Respir Crit Care Med· June 2010

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Novel recombinant Mycobacterium bovis BCG, ovine atadenovirus, and modified vaccinia virus Ankara vaccines combine to induce robust human immunodeficiency virus-specific CD4 and CD8 T-cell responses in rhesus macaques.
Maximillian Rosario, Richard Hopkins, John Fulkerson, Nicola Borthwick, Máire F Quigley, Jerald C Sadoff

J Virol· June 2010

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Update on research and development pipeline: tuberculosis vaccines.
Belinda Beresford, Jerald C Sadoff

Clin Infect Dis· May 2010

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Recombinant yellow fever vaccine virus 17D expressing simian immunodeficiency virus SIVmac239 gag induces SIV-specific CD8+ T-cell responses in rhesus macaques.
Myrna C Bonaldo, Mauricio A Martins, Richard Rudersdorf, Philip A Mudd, Jonah B Sacha, Jerald C Sadoff

J Virol· April 2010

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Non-clinical efficacy and safety of HyVac4:IC31 vaccine administered in a BCG prime-boost regimen.
Yasir A W Skeiky, Jes Dietrich, Todd M Lasco, Katherine Stagliano, Veerabadran Dheenadhayalan, Jerald C Sadoff

Vaccine· January 2010

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Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis.
Ronggai Sun, Yasir A W Skeiky, Angelo Izzo, Veerabadran Dheenadhayalan, Zakaria Imam, Jerald C Sadoff

Vaccine· July 2009

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Tuberculosis vaccine research: the impact of immunology.
Lewellys F Barker, Michael J Brennan, Peri K Rosenstein, Jerald C Sadoff

Curr Opin Immunol· June 2009

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A new recombinant bacille Calmette-Guérin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteers.
Daniel F Hoft, Azra Blazevic, Getahun Abate, Willem A Hanekom, Gilla Kaplan, Jerald C Sadoff

J Infect Dis· November 2008

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Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analyses.
Anat Zvi, Naomi Ariel, John Fulkerson, Jerald C Sadoff, Avigdor Shafferman

BMC Med Genomics· May 2008

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Correlates, surrogates, and vaccines.
Jerald C Sadoff, Janet Wittes

J Infect Dis· November 2007

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Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon.
Katarina Radosevic, Catharina W Wieland, Ariane Rodriguez, Gerrit Jan Weverling, Ratna Mintardjo, Jerald C Sadoff

Infect Immun· August 2007

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Evaluation of cellular immune responses in subjects chronically infected with HIV type 1.
Tong-Ming Fu, Sheri A Dubey, Devan V Mehrotra, Daniel C Freed, Wendy L Trigona, Jerald C Sadoff

AIDS Res Hum Retroviruses· January 2007

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Advances in tuberculosis vaccine strategies.
Yasir A W Skeiky, Jerald C Sadoff

Nat Rev Microbiol· June 2006

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Vaccine risk and benefit in the developing world.
Jerald C Sadoff

Health Aff (Millwood)· December 2005

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The role of "go no-go" decisions in TB vaccine development.
Jerald C Sadoff, David Hone

Microbes Infect· May 2005

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Protective efficacy of a second pneumococcal conjugate vaccine against pneumococcal acute otitis media in infants and children: randomized, controlled trial of a 7-valent pneumococcal polysaccharide-meningococcal outer membrane protein complex conjugate vaccine in 1666 children.
Terhi Kilpi, Heidi Ahman, Jukka Jokinen, Kari S Lankinen, Arto Palmu, Jerald C Sadoff

Clin Infect Dis· November 2003

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