Publications by authors named "Jeremy Blaydes"

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Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma.
Charles N Birts, Constantinos Savva, Stéphanie A Laversin, Alicia Lefas, Jamie Krishnan, Jeremy P Blaydes

Sci Rep· May 2022

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Glycolysis, via NADH-dependent dimerisation of CtBPs, regulates hypoxia-induced expression of CAIX and stem-like breast cancer cell survival.
Mira Kreuzer, Arindam Banerjee, Charles N Birts, Matthew Darley, Ali Tavassoli, Jeremy P Blaydes

FEBS Lett· September 2020

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p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators.
Charles N Birts, Arindam Banerjee, Matthew Darley, Charles R Dunlop, Sarah Nelson, Jeremy P Blaydes

Sci Signal· May 2020

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Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization.
Arindam Banerjee, Charles N Birts, Matthew Darley, Rachel Parker, Alex H Mirnezami, Jeremy P Blaydes

Carcinogenesis· July 2019

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Glycolysis Regulates Human Embryonic Stem Cell Self-Renewal under Hypoxia through HIF-2α and the Glycolytic Sensors CTBPs.
Sophie A Arthur, Jeremy P Blaydes, Franchesca D Houghton

Stem Cell Reports· April 2019

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HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma.
Jason C Fleming, Jeongmin Woo, Karwan Moutasim, Massimiliano Mellone, Steven J Frampton, Jeremy P Blaydes

Br J Cancer· February 2019

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The effects of restricted glycolysis on stem-cell like characteristics of breast cancer cells.
Arindam Banerjee, Pardis Arvinrad, Matthew Darley, Stéphanie A Laversin, Rachel Parker, Jeremy P Blaydes

Oncotarget· May 2018

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Novel splice-switching oligonucleotide promotes BRCA1 aberrant splicing and susceptibility to PARP inhibitor action.
Lindsay D Smith, Flávia Leme de Calais, Michela Raponi, Massimiliano Mellone, Emanuele Buratti, Jeremy P Blaydes

Int J Cancer· April 2017

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Synthesis and evaluation of a (3R,6S,9S)-2-oxo-1-azabicyclo[4.3.0]nonane scaffold as a mimic of Xaa-trans-Pro in poly-L-proline type II helix conformation.
Boris Aillard, Jeremy D Kilburn, Jeremy P Blaydes, Graham J Tizzard, Stuart Findlow

Org Biomol Chem· April 2015

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Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma.
Timothy J Underwood, Annette L Hayden, Mathieu Derouet, Edwin Garcia, Fergus Noble, Jeremy P Blaydes

J Pathol· February 2015

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Senescence induction in renal carcinoma cells by Nutlin-3: a potential therapeutic strategy based on MDM2 antagonism.
Radosław Polański, Aidan P Noon, Jeremy Blaydes, Anna Phillips, Carlos P Rubbi

Cancer Lett· October 2014

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Transcription of click-linked DNA in human cells.
Charles N Birts, A Pia Sanzone, Afaf H El-Sagheer, Jeremy P Blaydes, Tom Brown

Angew Chem Int Ed Engl· February 2014

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Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Suzanne A Eccles, Eric O Aboagye, Simak Ali, Annie S Anderson, Jo Armes, Jeremy P Blaydes

Breast Cancer Res· October 2013

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A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells.
Charles N Birts, Sharandip K Nijjar, Charlotte A Mardle, Franciane Hoakwie, Patrick J Duriez, Jeremy P Blaydes

Chem Sci· August 2013

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Targeting tumour proliferation with a small-molecule inhibitor of AICAR transformylase homodimerization.
Ian B Spurr, Charles N Birts, Francesco Cuda, Stephen J Benkovic, Jeremy P Blaydes

Chembiochem· July 2012

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Down-regulation of DNA mismatch repair enhances initiation and growth of neuroblastoma and brain tumour multicellular spheroids.
Samuel L Collins, Rodolphe Hervé, C W Keevil, Jeremy P Blaydes, Jeremy S Webb

PLoS One· May 2012

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Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4.
Hilmar M Warenius, Jeremy D Kilburn, Jon W Essex, Richard I Maurer, Jeremy P Blaydes

Mol Cancer· June 2011

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A comparison of primary oesophageal squamous epithelial cells with HET-1A in organotypic culture.
Timothy J Underwood, Mathieu F Derouet, Michael J White, Fergus Noble, Karwan A Moutasim, Jeremy P Blaydes

Biol Cell· December 2010

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The role of MNK proteins and eIF4E phosphorylation in breast cancer cell proliferation and survival.
Matthew J Wheater, Peter Wm Johnson, Jeremy P Blaydes

Cancer Biol Ther· October 2010

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HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity.
Anna Phillips, Amina Teunisse, Suzanne Lam, Kirsten Lodder, Matthew Darley, Jeremy P Blaydes

J Biol Chem· September 2010

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Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance.
Charles N Birts, Rachael Harding, Gehan Soosaipillai, Trisha Halder, Ali Azim-Araghi, Jeremy P Blaydes

Biol Cell· January 2010

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CtBPs promote cell survival through the maintenance of mitotic fidelity.
Lee M Bergman, Charles N Birts, Matthew Darley, Brian Gabrielli, Jeremy P Blaydes

Mol Cell Biol· August 2009

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Dissection of the functional interaction between p53 and the embryonic proto-oncoprotein PAX3.
Timothy J Underwood, Jay Amin, Karen A Lillycrop, Jeremy P Blaydes

FEBS Lett· December 2007

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Role of the unique N-terminal domain of CtBP2 in determining the subcellular localisation of CtBP family proteins.
Lee M Bergman, Laila Morris, Matthew Darley, Alexander H Mirnezami, Samal C Gunatilake, Jeremy P Blaydes

BMC Cell Biol· September 2006

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Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines.
Gavin Babbage, Christian H Ottensmeier, Jeremy Blaydes, Freda K Stevenson, Surinder S Sahota

Cancer Res· April 2006

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