Publications by authors named "Lindsay D Smith"

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The evolution of health data ecosystems: An international survey.
Jordan P Lerner-Ellis, E Magda Price, Shazia Subhani, Tiffany Boughtwood, Marie-Jo Brion, Lindsay D Smith

Am J Hum Genet· August 2025

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International Precision Child Health Partnership (IPCHiP): an initiative to accelerate discovery and improve outcomes in rare pediatric disease.
Katherine B Howell, Susan M White, Amy McTague, Alissa M D'Gama, Gregory Costain, Lindsay D Smith

NPJ Genom Med· February 2025

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Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment.
Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Lindsay D Smith

Blood· August 2022

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The GA4GH Phenopacket schema defines a computable representation of clinical data.
Julius O B Jacobsen, Michael Baudis, Gareth S Baynam, Jacques S Beckmann, Sergi Beltran, Lindsay D Smith

Nat Biotechnol· June 2022

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B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells.
Annabel R Minton, Lindsay D Smith, Dean J Bryant, Jonathan C Strefford, Francesco Forconi

Explor Target Antitumor Ther· February 2022

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Preclinical Evaluation of a Novel SHIP1 Phosphatase Activator for Inhibition of PI3K Signaling in Malignant B Cells.
Elizabeth A Lemm, Beatriz Valle-Argos, Lindsay D Smith, Johanna Richter, Yohannes Gebreselassie

Clin Cancer Res· April 2020

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BCR signaling contributes to autophagy regulation in chronic lymphocytic leukemia.
Lindsay D Smith, Annabel R Minton, Matthew D Blunt, Laura I Karydis, David A Dutton

Leukemia· February 2020

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A study of splicing mutations in disorders of sex development.
Flavia Leme de Calais, Lindsay D Smith, Michela Raponi, Andréa Trevas Maciel-Guerra, Gil Guerra-Junior

Sci Rep· November 2017

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The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia.
Matthew D Blunt, Stefan Koehrer, Rachel C Dobson, Marta Larrayoz, Sarah Wilmore, Lindsay D Smith

Clin Cancer Res· May 2017

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Novel splice-switching oligonucleotide promotes BRCA1 aberrant splicing and susceptibility to PARP inhibitor action.
Lindsay D Smith, Flávia Leme de Calais, Michela Raponi, Massimiliano Mellone, Emanuele Buratti

Int J Cancer· April 2017

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IL-4 enhances expression and function of surface IgM in CLL cells.
Maria M Aguilar-Hernandez, Matthew D Blunt, Rachel Dobson, Alison Yeomans, Stephen Thirdborough, Lindsay D Smith

Blood· June 2016

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The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model.
Matthew D Blunt, Matthew J Carter, Marta Larrayoz, Lindsay D Smith, Maria Aguilar-Hernandez

Blood· June 2015

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BRCA1 exon 11 a model of long exon splicing regulation.
Michela Raponi, Lindsay D Smith, Marco Silipo, Cristiana Stuani, Emanuele Buratti

RNA Biol· January 2015

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A targeted oligonucleotide enhancer of SMN2 exon 7 splicing forms competing quadruplex and protein complexes in functional conditions.
Lindsay D Smith, Rachel L Dickinson, Christian M Lucas, Alex Cousins, Alexey A Malygin

Cell Rep· October 2014

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Comprehensive annotation of splice junctions supports pervasive alternative splicing at the BRCA1 locus: a report from the ENIGMA consortium.
Mara Colombo, Marinus J Blok, Phillip Whiley, Marta Santamariña, Sara Gutiérrez-Enríquez, Lindsay Denise Smith

Hum Mol Genet· July 2014

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Intron retention in the alternatively spliced region of RON results from weak 3' splice site recognition.
Lindsay D Smith, Christian M Lucas, Ian C Eperon

PLoS One· June 2014

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Design principles for bifunctional targeted oligonucleotide enhancers of splicing.
Nicholas Owen, Haiyan Zhou, Alexey A Malygin, Jason Sangha, Lindsay D Smith

Nucleic Acids Res· September 2011

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