Publications by authors named "Matthew D Blunt"

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CD40L and IL-4 suppress NK cell-mediated antibody-dependent cellular cytotoxicity through the HLA-E:NKG2A axis.
Lara V Graham, Ludmila Horehajova, Marco V Haselager, Jack G Fisher, Jamie Lee Roos, Matthew D Blunt

Immunother Adv· September 2025

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NK Cells in Health and Disease.
Matthew D Blunt

Biomedicines· May 2025

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Modulation of anti-tumour immunity by XPO1 inhibitors.
Jack G Fisher, Laura G Bartlett, Trinayan Kashyap, Christopher J Walker, Salim I Khakoo, Matthew D Blunt

Explor Target Antitumor Ther· April 2025

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KIR2DS2+ NK cells in cancer patients demonstrate high activation in response to tumour-targeting antibodies.
Lara V Graham, Jack G Fisher, Amber D P Doyle, Ben Sale, Luis Del Rio, Matthew D Blunt

Front Oncol· September 2024

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The nuclear export protein XPO1 provides a peptide ligand for natural killer cells.
Matthew D Blunt, Hayden Fisher, Ralf B Schittenhelm, Berenice Mbiribindi, Rebecca Fulton

Sci Adv· August 2024

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Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity.
Jack G Fisher, Lara V Graham, Matthew D Blunt

Oncotarget· July 2024

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NK Cells in the Lymph Nodes and Their Role in Anti-Tumour Immunity.
Lara V Graham, Salim I Khakoo, Matthew D Blunt

Biomedicines· July 2024

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Targeting CD161 in B-cell malignancies.
Matthew D Blunt

Blood· March 2024

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Harnessing natural killer cell effector function against cancer.
Matthew D Blunt, Salim I Khakoo

Immunother Adv· December 2023

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Targeting KIR as a novel approach to improve CAR-NK cell function.
Lara V Graham, Jack G Fisher, Salim I Khakoo, Matthew D Blunt

J Transl Genet Genom· December 2023

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XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression.
Jack G Fisher, Amber D P Doyle, Lara V Graham, Shreyanshi Sonar, Ben Sale, Matthew D Blunt

Leukemia· October 2023

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Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL.
Dean Bryant, Lindsay Smith, Karly Rai Rogers-Broadway, Laura Karydis, Jeongmin Woo, Matthew D Blunt

Leukemia· July 2023

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Disruption of the NKG2A:HLA-E Immune Checkpoint Axis to Enhance NK Cell Activation against Cancer.
Jack G Fisher, Amber D P Doyle, Lara V Graham, Salim I Khakoo, Matthew D Blunt

Vaccines (Basel)· November 2022

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KIR2DS2 Expression Identifies NK Cells With Enhanced Anticancer Activity.
Matthew D Blunt, Andres Vallejo Pulido, Jack G Fisher, Lara V Graham, Amber D P Doyle

J Immunol· July 2022

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Selinexor Enhances NK Cell Activation Against Malignant B Cells Downregulation of HLA-E.
Jack G Fisher, Christopher J Walker, Amber Dp Doyle, Peter Wm Johnson, Francesco Forconi, Matthew D Blunt

Front Oncol· December 2021

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The role of NK cells in oncolytic viral therapy: a focus on hepatocellular carcinoma.
Frazer Warricker, Salim I Khakoo, Matthew D Blunt

J Transl Genet Genom· August 2021

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Peptide: MHC-based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors.
Pauline Rettman, Matthew D Blunt, Rebecca J Fulton, Andres F Vallejo, Leidy Y Bastidas-Legarda

J Immunother Cancer· May 2021

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Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis.
Theresa J Hydes, Matthew D Blunt, Jennifer Naftel, Andres F Vallejo, Grégory Seumois

Front Immunol· November 2020

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BCR signaling contributes to autophagy regulation in chronic lymphocytic leukemia.
Lindsay D Smith, Annabel R Minton, Matthew D Blunt, Laura I Karydis, David A Dutton

Leukemia· February 2020

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Activating killer cell immunoglobulin-like receptors: Detection, function and therapeutic use.
Matthew D Blunt, Salim I Khakoo

Int J Immunogenet· February 2020

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A novel antibody combination to identify KIR2DS2 natural killer cells in KIR2DL3/L2/S2 heterozygous donors.
Matthew D Blunt, Pauline Rettman, Leidy Y Bastidas-Legarda, Rebecca Fulton, Valentina Capizzuto

HLA· January 2019

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The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia.
Matthew D Blunt, Stefan Koehrer, Rachel C Dobson, Marta Larrayoz, Sarah Wilmore

Clin Cancer Res· May 2017

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Hydrogen Peroxide Triggers a Dual Signaling Axis To Selectively Suppress Activated Human T Lymphocyte Migration.
Jennifer A Ball, Isabella Vlisidou, Matthew D Blunt, Will Wood, Stephen G Ward

J Immunol· May 2017

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Releasing the brakes on BTK-targeting miRNA.
Matthew D Blunt, Andrew J Steele

Blood· December 2016

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To BH3 profile or not to BH3 profile.
Matthew D Blunt, Andrew J Steele

Blood· June 2016

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