Publications by authors named "Jeremy R Graff"

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Imprime PGG Enhances Anti-Tumor Effects of Tumor-Targeting, Anti-Angiogenic, and Immune Checkpoint Inhibitor Antibodies.
Anissa S H Chan, Takashi O Kangas, Xiaohong Qiu, Mark T Uhlik, Ross B Fulton, Jeremy R Graff

Front Oncol· May 2022

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Immune Pharmacodynamic Responses of the Novel Cancer Immunotherapeutic Imprime PGG in Healthy Volunteers.
Nandita Bose, Nadine R Ottoson, Xiaohong Qiu, Ben Harrison, Jamie R Lowe, Jeremy R Graff

J Immunol· May 2019

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Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation.
Anissa S H Chan, Adria Bykowski Jonas, Xiaohong Qiu, Nadine R Ottoson, Richard M Walsh, Jeremy R Graff

PLoS One· July 2017

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Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers.
Rebecca Lock, Rachel Ingraham, Ophélia Maertens, Abigail L Miller, Nelly Weledji, Jeremy R Graff

J Clin Invest· June 2016

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Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma.
Julia H Carter, James A Deddens, Nelson Reed Spaulding, Denise Lucas, Bruce M Colligan, Jeremy R Graff

Br J Cancer· February 2016

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Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes.
Christos G Gkogkas, Arkady Khoutorsky, Ruifeng Cao, Seyed Mehdi Jafarnejad, Masha Prager-Khoutorsky, Jeremy R Graff

Cell Rep· December 2014

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Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide.
Blake A Jacobson, Saritha C Thumma, Joseph Jay-Dixon, Manish R Patel, K Dubear Kroening, Jeremy R Graff

PLoS One· June 2014

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Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity.
Robert M Campbell, Bryan D Anderson, Nathan A Brooks, Harold B Brooks, Edward M Chan, Jeremy R Graff

Mol Cancer Ther· February 2014

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LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
S Betty Yan, Victoria L Peek, Rose Ajamie, Sean G Buchanan, Jeremy R Graff

Invest New Drugs· August 2013

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Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors.
Jessica K Altman, Amy Szilard, Bruce W Konicek, Philip W Iversen, Barbara Kroczynska, Jeremy R Graff

Blood· May 2013

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Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.
Bruce W Konicek, Jennifer R Stephens, Ann M McNulty, Nathaniel Robichaud, Robert B Peery, Jeremy R Graff

Cancer Res· March 2011

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Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis.
Chad A Dumstorf, Bruce W Konicek, Ann M McNulty, Stephen H Parsons, Luc Furic, Jeremy R Graff

Mol Cancer Ther· December 2010

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eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival.
Jeremy R Graff, Bruce W Konicek, Rebecca L Lynch, Chad A Dumstorf, Michele S Dowless

Cancer Res· May 2009

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Targeting the eIF4F translation initiation complex for cancer therapy.
Bruce W Konicek, Chad A Dumstorf, Jeremy R Graff

Cell Cycle· August 2008

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Targeting the eukaryotic translation initiation factor 4E for cancer therapy.
Jeremy R Graff, Bruce W Konicek, Julia H Carter, Eric G Marcusson

Cancer Res· February 2008

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Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity.
Jeremy R Graff, Bruce W Konicek, Thomas M Vincent, Rebecca L Lynch, David Monteith

J Clin Invest· September 2007

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Int7G24A variant of transforming growth factor-beta receptor type I is associated with invasive breast cancer.
Taiping Chen, Chad R Jackson, Andrew Link, Michael P Markey, Bruce M Colligan, Jeremy R Graff

Clin Cancer Res· January 2006

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The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts.
Jeremy R Graff, Ann M McNulty, Kimberly Ross Hanna, Bruce W Konicek, Rebecca L Lynch

Cancer Res· August 2005

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The progression of LNCaP human prostate cancer cells to androgen independence involves decreased FOXO3a expression and reduced p27KIP1 promoter transactivation.
Rebecca L Lynch, Bruce W Konicek, Ann M McNulty, Kimberly R Hanna, Jason E Lewis, Jeremy R Graff

Mol Cancer Res· March 2005

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An intronic variant of the TGFBR1 gene is associated with carcinomas of the kidney and bladder.
Taiping Chen, Chad Jackson, Ben Costello, Natalie Singer, Bruce Colligan, Jeremy R Graff

Int J Cancer· November 2004

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Expression levels of protein kinase C-alpha in non-small-cell lung cancer.
Michael Lahn, Chen Su, Shuyu Li, Marcio Chedid, Kimberly R Hanna, Jeremy R Graff

Clin Lung Cancer· November 2004

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Pak-1 expression increases with progression of colorectal carcinomas to metastasis.
Julia H Carter, Larry E Douglass, James A Deddens, Bruce M Colligan, Tejal R Bhatt, Jeremy R Graff

Clin Cancer Res· May 2004

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eIF-4E expression and its role in malignancies and metastases.
Arrigo De Benedetti, Jeremy R Graff

Oncogene· April 2004

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The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model.
Blake Lee Neubauer, Ann M McNulty, Marcio Chedid, Keyue Chen, Robin L Goode, Jeremy R Graff

Cancer Res· September 2003

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Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs.
Jeremy R Graff, Stephen G Zimmer

Clin Exp Metastasis· May 2003

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