Publications by authors named "Jessica Caciolla"

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Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis.
Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Jessica Caciolla

J Med Chem· January 2024

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Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment.
Silvia Gobbi, Silvia Martini, Riccardo Rozza, Angelo Spinello, Jessica Caciolla

Molecules· March 2023

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Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy.
Jessica Caciolla, Silvia Martini, Angelo Spinello, Federica Belluti, Alessandra Bisi

Eur J Med Chem· December 2022

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Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One.
Alessandra Salerno, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Eleonora Testi

J Med Chem· July 2022

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Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design.
Annarita Fiorillo, Gianni Colotti, Cécile Exertier, Anastasia Liuzzi, Francesca Seghetti, Jessica Caciolla

Front Mol Biosci· July 2022

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Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer.
Jessica Caciolla, Silvia Martini, Angelo Spinello, Matic Pavlin, Eleonora Turrini

Eur J Med Chem· November 2021

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Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer.
Jessica Caciolla, Giovanna Picone, Giovanna Farruggia, Dario Valenti, Angela Rampa

Bioorg Chem· January 2021

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Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target.
Jessica Caciolla, Alessandra Bisi, Federica Belluti, Angela Rampa, Silvia Gobbi

Molecules· November 2020

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Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors.
Jessica Caciolla, Angelo Spinello, Silvia Martini, Alessandra Bisi, Nadia Zaffaroni

ACS Med Chem Lett· May 2020

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Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors.
Giulio Poli, Margherita Lapillo, Carlotta Granchi, Jessica Caciolla, Nayla Mouawad

J Enzyme Inhib Med Chem· December 2018

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