Publications by authors named "Jessica P Alexander"

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Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators.
Jason R Clapper, Cassandra L Henry, Micah J Niphakis, Anna M Knize, Aundrea R Coppola, Jessica P Alexander

J Pharmacol Exp Ther· December 2018

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Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders.
Justin S Cisar, Olivia D Weber, Jason R Clapper, Jacqueline L Blankman, Cassandra L Henry, Jessica P Alexander

J Med Chem· October 2018

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Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain.
Harry R Chobanian, Yan Guo, Ping Liu, Marc D Chioda, Selena Fung, Jessica P Alexander

ACS Med Chem Lett· June 2014

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Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction.
Lily Y Moy, Yanlin Jia, Michael Caniga, Gissela Lieber, Malgorzata Gil, Jessica P Alexander

Am J Respir Cell Mol Biol· December 2013

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The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.
William R Marrs, Jacqueline L Blankman, Eric A Horne, Aurore Thomazeau, Yi Hsing Lin, Jessica P Alexander

Nat Neurosci· August 2010

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Gamma-glutamyl hydrolase: kinetic characterization of isopeptide hydrolysis using fluorogenic substrates.
Jessica P Alexander, Thomas J Ryan, David P Ballou, James K Coward

Biochemistry· January 2008

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Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.
Kyunghye Ahn, Douglas S Johnson, Laura R Fitzgerald, Marya Liimatta, Andrea Arendse, Jessica P Alexander

Biochemistry· November 2007

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The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases.
Jessica P Alexander, Benjamin F Cravatt

J Am Chem Soc· August 2006

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Mechanism of carbamate inactivation of FAAH: implications for the design of covalent inhibitors and in vivo functional probes for enzymes.
Jessica P Alexander, Benjamin F Cravatt

Chem Biol· November 2005

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Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.
Edward D Högestätt, Bo A G Jönsson, Anna Ermund, David A Andersson, Henrik Björk, Jessica P Alexander

J Biol Chem· September 2005

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