Publications by authors named "Jessica Thomaston"

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Transient water wires mediate selective proton transport in designed channel proteins.
Huong T Kratochvil, Laura C Watkins, Marco Mravic, Jessica L Thomaston, John M Nicoludis

Nat Chem· July 2023

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Rimantadine Binds to and Inhibits the Influenza A M2 Proton Channel without Enantiomeric Specificity.
Jessica L Thomaston, Marley L Samways, Athina Konstantinidi, Chunlong Ma, Yanmei Hu

Biochemistry· August 2021

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X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance.
Jessica L Thomaston, Athina Konstantinidi, Lijun Liu, George Lambrinidis, Jingquan Tan

Biochemistry· February 2020

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X-ray Crystal Structure of the Influenza A M2 Proton Channel S31N Mutant in Two Conformational States: An Open and Shut Case.
Jessica L Thomaston, Yibing Wu, Nicholas Polizzi, Lijun Liu, Jun Wang

J Am Chem Soc· July 2019

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Packing of apolar side chains enables accurate design of highly stable membrane proteins.
Marco Mravic, Jessica L Thomaston, Maxwell Tucker, Paige E Solomon, Lijun Liu

Science· March 2019

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Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters.
Jessica L Thomaston, Nicholas F Polizzi, Athina Konstantinidi, Jun Wang, Antonios Kolocouris

J Am Chem Soc· November 2018

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XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction.
Jessica L Thomaston, Rahel A Woldeyes, Takanori Nakane, Ayumi Yamashita, Tomoyuki Tanaka

Proc Natl Acad Sci U S A· December 2017

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Crystal structure of the drug-resistant S31N influenza M2 proton channel.
Jessica L Thomaston, William F DeGrado

Protein Sci· August 2016

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High-density grids for efficient data collection from multiple crystals.
Elizabeth L Baxter, Laura Aguila, Roberto Alonso-Mori, Christopher O Barnes, Christopher A Bonagura, Jessica Thomaston

Acta Crystallogr D Struct Biol· January 2016

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High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction.
Jessica L Thomaston, Mercedes Alfonso-Prieto, Rahel A Woldeyes, James S Fraser, Michael L Klein

Proc Natl Acad Sci U S A· November 2015

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C-terminal juxtamembrane region of full-length M2 protein forms a membrane surface associated amphipathic helix.
Shenstone Huang, Bryan Green, Megan Thompson, Richard Chen, Jessica Thomaston

Protein Sci· March 2015

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Detection of drug-induced conformational change of a transmembrane protein in lipid bilayers using site-directed spin labeling.
Jessica L Thomaston, Phuong A Nguyen, Emily C Brown, Mary Alice Upshur, Jun Wang

Protein Sci· January 2013

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