Publications by authors named "Jessica Van Setten"

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Technical and legal aspects of federated learning in bioinformatics: applications, challenges and opportunities.
Daniele Malpetti, Marco Scutari, Francesco Gualdi, Jessica van Setten, Sander van der Laan

Front Digit Health· December 2025

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Proteomics-based clustering outperforms clinical clustering in identifying people with heart failure with distinct outcomes.
Marion van Vugt, Ruicong She, Isabella Kardys, Teun B Petersen, Marie de Bakker, Jessica van Setten

Commun Med (Lond)· November 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Jessica van Setten

Nat Med· September 2025

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Genetically determined ancestry associates with morphological and molecular carotid plaque features.
Nima Fahim, Tim R Sakkers, Joost Hoekstra, Dominique P V de Kleijn, Michal Mokry, Jessica van Setten

medRxiv· June 2025

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Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.
Albert Henry, Xiaodong Mo, Chris Finan, Mark D Chaffin, Doug Speed, Jessica van Setten

Nat Genet· April 2025

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Elevated Plasma Complement Factors in CRB1-Associated Inherited Retinal Dystrophies.
Lude Moekotte, Joke H de Boer, Sanne Hiddingh, Aafke de Ligt, Xuan-Thanh-An Nguyen, Jessica van Setten

Invest Ophthalmol Vis Sci· February 2025

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Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.
Sean L Zheng, Albert Henry, Douglas Cannie, Michael Lee, David Miller, Jessica van Setten

Nat Genet· December 2024

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Integrating metabolomics and proteomics to identify novel drug targets for heart failure and atrial fibrillation.
Marion van Vugt, Chris Finan, Sandesh Chopade, Rui Providencia, Connie R Bezzina, Jessica van Setten

Genome Med· October 2024

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Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target.
Tanmoy Roychowdhury, Derek Klarin, Michael G Levin, Joshua M Spin, Yae Hyun Rhee, Jessica van Setten

Nat Genet· November 2023

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Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.
Maryam Kavousi, Maxime M Bos, Hanna J Barnes, Christian L Lino Cardenas, Doris Wong, Jessica van Setten

Nat Genet· October 2023

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Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human.
Julia E Niskanen, Åsa Ohlsson, Ingrid Ljungvall, Michaela Drögemüller, Robert F Ernst, Jessica van Setten

Genome Med· September 2023

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids.
Sarah E Graham, Shoa L Clarke, Kuan-Han H Wu, Stavroula Kanoni, Greg J M Zajac, Jessica van Setten

Nature· June 2023

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Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity.
Amand F Schmidt, Mimount Bourfiss, Abdulrahman Alasiri, Esther Puyol-Anton, Sandesh Chopade, Jessica van Setten

Sci Adv· April 2023

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The association between a genetic variant in the gene, metabolic parameters and vascular disease in patients at high cardiovascular risk.
Britt E Heidemann, Frank Lj Visseren, Jessica van Setten, A David Marais, Charlotte Koopal

Cardiovasc Endocrinol Metab· March 2023

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Effect of tissue-grouped regulatory variants associated to type 2 diabetes in related secondary outcomes.
Daiane Hemerich, Roelof A J Smit, Michael Preuss, Lauren Stalbow, Sander W van der Laan, Jessica van Setten

Sci Rep· March 2023

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LoFTK: a framework for fully automated calculation of predicted Loss-of-Function variants and genes.
Abdulrahman Alasiri, Konrad J Karczewski, Brian Cole, Bao-Li Loza, Jason H Moore, Jessica van Setten

BioData Min· February 2023

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Cardiac MRI to guide heart failure and atrial fibrillation drug discovery: a Mendelian randomization analysis.
Amand Schmidt, Chris Finan, Mimount Bourfiss, Birgitta Velthuis, Esther Puyol-Antón, Jessica van Setten

Res Sq· February 2023

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Prevalence and Disease Expression of Pathogenic and Likely Pathogenic Variants Associated With Inherited Cardiomyopathies in the General Population.
Mimount Bourfiss, Marion van Vugt, Abdulrahman I Alasiri, Bram Ruijsink, Jessica van Setten

Circ Genom Precis Med· December 2022

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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Stavroula Kanoni, Sarah E Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Jessica van Setten

Genome Biol· December 2022

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A saturated map of common genetic variants associated with human height.
Loïc Yengo, Sailaja Vedantam, Eirini Marouli, Julia Sidorenko, Eric Bartell, Jessica van Setten

Nature· October 2022

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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Shweta Ramdas, Jonathan Judd, Sarah E Graham, Stavroula Kanoni, Yuxuan Wang, Jessica van Setten

Am J Hum Genet· August 2022

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Genetic variants associated with low-density lipoprotein cholesterol and systolic blood pressure and the risk of recurrent cardiovascular disease in patients with established vascular disease.
Eline H Groenland, Britt E Heidemann, Sander W van der Laan, Jessica van Setten, Charlotte Koopal

Atherosclerosis· June 2022

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Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.
Tessa Schillemans, Vinicius Tragante, Buamina Maitusong, Bruna Gigante, Sharon Cresci, Jessica van Setten

Front Physiol· June 2022

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A Regional Burden of Sequence-Level Variation in the 22q11.2 Region Influences Schizophrenia Risk and Educational Attainment.
Elemi J Breetvelt, Karel C Smit, Jessica van Setten, Daniele Merico, Xiao Wang

Biol Psychiatry· April 2022

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The power of genetic diversity in genome-wide association studies of lipids.
Sarah E Graham, Shoa L Clarke, Kuan-Han H Wu, Stavroula Kanoni, Greg J M Zajac, Jessica van Setten

Nature· December 2021

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