Publications by authors named "Mark D Chaffin"

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Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.
Albert Henry, Xiaodong Mo, Chris Finan, Mark D Chaffin, Doug Speed

Nat Genet· April 2025

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Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk.
Seung Hoan Choi, Sean J Jurgens, Ling Xiao, Matthew C Hill, Christopher M Haggerty, Mark D Chaffin

Nat Genet· March 2025

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Transcriptional profile of the rat cardiovascular system at single-cell resolution.
Alessandro Arduini, Stephen J Fleming, Ling Xiao, Amelia W Hall, Amer-Denis Akkad, Mark D Chaffin

Cell Rep· January 2025

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Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience.
Sean J Jurgens, Joel T Rämö, Daria R Kramarenko, Leonoor F J M Wijdeveld, Jan Haas, Mark D Chaffin

Nat Genet· December 2024

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Publisher Correction: Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience.
Sean J Jurgens, Joel T Rämö, Daria R Kramarenko, Leonoor F J M Wijdeveld, Jan Haas, Mark D Chaffin

Nat Genet· December 2024

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Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender.
Stephen J Fleming, Mark D Chaffin, Alessandro Arduini, Amer-Denis Akkad, Eric Banks

Nat Methods· September 2023

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Transfer learning enables predictions in network biology.
Christina V Theodoris, Ling Xiao, Anant Chopra, Mark D Chaffin, Zeina R Al Sayed

Nature· June 2023

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The Genetic Determinants of Aortic Distention.
James P Pirruccello, Joel T Rämö, Seung Hoan Choi, Mark D Chaffin, Shinwan Kany

J Am Coll Cardiol· April 2023

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Genetic analysis of right heart structure and function in 40,000 people.
James P Pirruccello, Paolo Di Achille, Victor Nauffal, Mahan Nekoui, Samuel F Friedman, Mark D Chaffin

Nat Genet· June 2022

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Deep learning enables genetic analysis of the human thoracic aorta.
James P Pirruccello, Mark D Chaffin, Elizabeth L Chou, Stephen J Fleming, Honghuang Lin

Nat Genet· January 2022

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Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.
George Hindy, Peter Dornbos, Mark D Chaffin, Dajiang J Liu, Minxian Wang

Am J Hum Genet· January 2022

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The genomics of heart failure: design and rationale of the HERMES consortium.
R Thomas Lumbers, Sonia Shah, Honghuang Lin, Tomasz Czuba, Albert Henry, Mark D Chaffin

ESC Heart Fail· December 2021

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SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Nedyalka Valkov, Avash Das, Nathan R Tucker, Guoping Li, Ane M Salvador, Mark D Chaffin

Life Sci Alliance· December 2021

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Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis.
Seung Hoan Choi, Sean J Jurgens, Christopher M Haggerty, Amelia W Hall, Jennifer L Halford, Mark D Chaffin

Circ Genom Precis Med· August 2021

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.
Ioanna Ntalla, Lu-Chen Weng, James H Cartwright, Amelia Weber Hall, Gardar Sveinbjornsson, Mark D Chaffin

Nat Commun· May 2020

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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Sonia Shah, Albert Henry, Carolina Roselli, Honghuang Lin, Garðar Sveinbjörnsson, Mark D Chaffin

Nat Commun· January 2020

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MetProc: Separating Measurement Artifacts from True Metabolites in an Untargeted Metabolomics Experiment.
Mark D Chaffin, Liu Cao, Amy A Deik, Clary B Clish, Frank B Hu

J Proteome Res· March 2019

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Author Correction: A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
Zhaozhong Zhu, Phil H Lee, Mark D Chaffin, Wonil Chung, Po-Ru Loh

Nat Genet· December 2018

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A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
Zhaozhong Zhu, Phil H Lee, Mark D Chaffin, Wonil Chung, Po-Ru Loh

Nat Genet· June 2018

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Multi-ethnic genome-wide association study for atrial fibrillation.
Carolina Roselli, Mark D Chaffin, Lu-Chen Weng, Stefanie Aeschbacher, Gustav Ahlberg

Nat Genet· June 2018

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Genomic and metabolic diversity of Marine Group I Thaumarchaeota in the mesopelagic of two subtropical gyres.
Brandon K Swan, Mark D Chaffin, Manuel Martinez-Garcia, Hilary G Morrison, Erin K Field

PLoS One· June 2015

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