Publications by authors named "Jiangli Yan"

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Intramolecular Ring-Opening Decomposition of Aryl Azetidines.
Guoyun Bai, Thomas N O'Connell, Michael A Brodney, Christopher R Butler, Lara C Czabaniuk, Jiangli Yan

ACS Med Chem Lett· October 2021

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Cyclic Peptide Design Guided by Residual Dipolar Couplings, J-Couplings, and Intramolecular Hydrogen Bond Analysis.
Kathleen A Farley, Ye Che, Armando Navarro-Vázquez, Chris Limberakis, Dennis Anderson, Jiangli Yan

J Org Chem· April 2019

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Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators.
Markus Boehm, Kevin Beaumont, Rhys Jones, Amit S Kalgutkar, Liying Zhang, Jiangli Yan

J Med Chem· December 2017

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Depletion of Gut-Resident CCR5 Cells for HIV Cure Strategies.
David Merriam, Connie Chen, Gema Méndez-Lagares, Kenneth A Rogers, Anthony J Michaels, Jiangli Yan

AIDS Res Hum Retroviruses· November 2017

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Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.
Katherine L Lee, Catherine M Ambler, David R Anderson, Brian P Boscoe, Andrea G Bree, Jiangli Yan

J Med Chem· July 2017

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Utilizing on- and off-line monitoring tools to follow a kinetic resolution step during flow synthesis.
Kathleen A Farley, Usa Reilly, Dennis P Anderson, Brian P Boscoe, Mark W Bundesmann, Jiangli Yan

Magn Reson Chem· April 2017

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Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism.
Kay Ahn, Markus Boehm, Matthew F Brown, Jessica Calloway, Ye Che, Jiangli Yan

ACS Chem Biol· September 2016

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Regio- and Enantioselective Synthesis of Azole Hemiaminal Esters by Lewis Base Catalyzed Dynamic Kinetic Resolution.
David W Piotrowski, Adam S Kamlet, Anne-Marie R Dechert-Schmitt, Jiangli Yan, Thomas A Brandt

J Am Chem Soc· April 2016

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Design and optimization of selective azaindole amide M1 positive allosteric modulators.
Jennifer E Davoren, Steven V O'Neil, Dennis P Anderson, Michael A Brodney, Lois Chenard, Jiangli Yan

Bioorg Med Chem Lett· January 2016

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The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats.
Derek M Erion, Amanda Lapworth, Paul A Amor, Guoyun Bai, Nicholas B Vera, Qingyun Yan, Jiangli Yan

PLoS One· February 2015

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High throughput method for the indirect detection of intramolecular hydrogen bonding.
Gilles H Goetz, William Farrell, Marina Shalaeva, Simone Sciabola, Dennis Anderson, Jiangli Yan

J Med Chem· April 2014

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Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target.
Karin Regnström, Jiangli Yan, Lan Nguyen, Kari Callaway, Yanli Yang

PLoS One· February 2014

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Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors.
Ying-Zi Xu, Shendong Yuan, Simeon Bowers, Roy K Hom, Wayman Chan, Jiangli Yan

Bioorg Med Chem Lett· May 2013

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Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interaction.
Rosa Cardoso, Robert Love, Carol L Nilsson, Simon Bergqvist, Dawn Nowlin, Jiangli Yan

Protein Sci· December 2012

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Homodimerization of the PAS-B domains of hypoxia-inducible factors.
Jing Zhu, Maria Martinez-Yamout, Rosa Cardoso, Jiangli Yan, Robert A Love

J Phys Chem B· June 2012

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Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery.
M Catherine Johnson, Qiyue Hu, Laura Lingardo, Rose Ann Ferre, Samantha Greasley, Jiangli Yan

J Comput Aided Mol Des· July 2011

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Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity.
Aaron A Thompson, Aihua Zou, Jiangli Yan, Rohit Duggal, Weidong Hao

Biochemistry· February 2009

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A
Application of residual dipolar couplings in organic compounds.
Jiangli Yan, Edward R Zartler

Magn Reson Chem· January 2005

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The absolute sign of J coupling constants determined using the order matrix calculation.
Jiangli Yan, Allen D Kline, Huaping Mo, Michael J Shapiro, Edward R Zartler

Magn Reson Chem· November 2004

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CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium.
Jiangli Yan, Yizhou Liu, Stephen M Lukasik, Nancy A Speck, John H Bushweller

Nat Struct Mol Biol· September 2004

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Using NMR for ligand discovery and optimization.
Hugo O Villar, Jiangli Yan, Mark R Hansen

Curr Opin Chem Biol· August 2004

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Complete relative stereochemistry of multiple stereocenters using only residual dipolar couplings.
Jiangli Yan, Frank Delaglio, Andreas Kaerner, Allen D Kline, Huaping Mo

J Am Chem Soc· April 2004

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RAMPED-UP NMR: multiplexed NMR-based screening for drug discovery.
Edward R Zartler, Jeffrey Hanson, Bryan E Jones, Allen D Kline, George Martin, Jiangli Yan

J Am Chem Soc· September 2003

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Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit.
Lina Zhang, Zhe Li, Jiangli Yan, Padmanava Pradhan, Takeshi Corpora

J Biol Chem· August 2003

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The effect of relaxation on the epitope mapping by saturation transfer difference NMR.
Jiangli Yan, Allen D Kline, Huaping Mo, Michael J Shapiro, Edward R Zartler

J Magn Reson· August 2003

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