Publications by authors named "Jianjun Xi"

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Discovery of novel 20S proteasome activators for hypoxic cardiomyocyte protection via endoplasmic reticulum stress alleviation.
Dan Wu, Yu Cao, Yubing Han, Linhao Xu, Han Han, Lixin Gao, Jianjun Xi

Bioorg Med Chem· January 2026

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Identification of Novel β-Lactam Derivatives as Proteasome Inhibitors for Antitumor Therapy.
Yu Cao, Gaoya Xu, Lixin Gao, Jingjing Sun, Lu Zhang, Jianjun Xi

Arch Pharm (Weinheim)· November 2025

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A "turn-on" fluorescence polyethyleneimine-based nanosensor chemosensor for sensing of l-lysine.
Qiao Tong, Weijie Shen, Lu Zhang, Yu Cao, Xi Zou, Rang Xiao Zhuang, Jianjun Xi

Talanta· October 2025

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Small nucleic acid drugs-the dawn of functional cure of chronic hepatitis B.
Lu Zhang, Yu Cao, Sijing Zhuang, Jingjing Sun, Qiao Tong, Jianjun Xi, Rangxiao Zhuang

Front Pharmacol· October 2025

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Mechanisms underlying altered ubiquitin-proteasome system activity during heart failure and pharmacological interventions.
Xiaofei Gao, Yu Cao, Hangyan Li, Faming Yu, Jianjun Xi, Rangxiao Zhuang

Eur J Med Chem· August 2025

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Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides.
Gongruixue Zeng, Gaoya Xu, Lixin Gao, Xiaoli Zheng, Xinglong Chi, Jianjun Xi, Jinxin Che, Xiaowu Dong

Bioorg Chem· March 2025

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Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection.
Qian Yu, Lixin Gao, Linhao Xu, Yubing Han, Yu Cao, Jianjun Xi, Jinxin Che, Xiaowu Dong

Bioorg Med Chem· December 2024

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Small molecules as modulators of the proteostasis machinery: Implication in cardiovascular diseases.
Zhiheng Yang, Yu Cao, Limin Kong, Jianjun Xi, Shourong Liu

Eur J Med Chem· January 2024

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Evaluation of the liver targeting and anti‑liver cancer activity of artesunate‑loaded and glycyrrhetinic acid‑coated nanoparticles.
Xu-Wang Pan, Jin-Song Huang, Shou-Rong Liu, Yi-Dan Shao, Jian-Jun Xi, Rang-Xiao Zhuang

Exp Ther Med· November 2023

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pH-Responsive and liver-targeting drug delivery system for combination delivery of artesunate with arsenic trioxide prodrug against hepatocellular carcinoma.
Xuwang Pan, Jinsong Huang, Shourong Liu, Yidan Shao, Jianjun Xi, Rangxiao Zhuang

Drug Dev Ind Pharm· August 2023

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Design, Synthesis and Biological Evaluation of Glycosylated Derivatives of Silibinin as Potential Anti-Tumor Agents.
Jian-Jun Xi, Yu Cao, Ruo-Yu He, Jian-Kang Zhang, Yan-Mei Zhao, Rang-Xiao Zhuang

Drug Des Devel Ther· July 2023

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Exploration of novel dihydroquinoxalinone derivatives as EGFR tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer.
Yu Cao, Xixuan Lu, Liping Fu, Tao Shi, Chong Zhang, Jianjun Xi

Bioorg Chem· June 2023

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Recent advances and future perspectives of noncompetitive proteasome inhibitors.
Gongruixue Zeng, Qian Yu, Rangxiao Zhuang, Huajian Zhu, Jiaan Shao, Jianjun Xi

Bioorg Chem· June 2023

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Proteasome, a Promising Therapeutic Target for Multiple Diseases Beyond Cancer.
Yu Cao, Huajian Zhu, Ruoyu He, Limin Kong, Jiaan Shao, Rangxiao Zhuang, Jianjun Xi

Drug Des Devel Ther· August 2021

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Regulation of Mitochondrial Function by Natural Products for the Treatment of Metabolic Associated Fatty Liver Disease.
Tingting Shi, Liping Yu, Rangxiao Zhuang, Jianjun Xi, Ruoyu He, Xingxin Yang

Can J Gastroenterol Hepatol· August 2021

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Optimization of piperidine constructed peptidyl derivatives as proteasome inhibitors.
Yanmei Zhao, Lei Xu, Jiankang Zhang, Mengmeng Zhang, Jingyi Lu, Jianjun Xi, Rangxiao Zhuang

Bioorg Med Chem· January 2021

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Protective effect of apigenin magnesium complex on HO-induced oxidative stress and inflammatory responses in rat hepatic stellate cells.
Xuwang Pan, Yidan Shao, Fugen Wang, Zhaobin Cai, Shourong Liu, Jianjun Xi, Rangxiao Zhuang

Pharm Biol· December 2020

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Preparation, evaluation, and cytotoxicity studies of artesunate-loaded glycyrrhetinic acid decorated PEG-PLGA nanoparticles.
Xuwang Pan, Shourong Liu, Liping Ju, Jianjun Xi, Ruoyu He, Rangxiao Zhuang

Drug Dev Ind Pharm· November 2020

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Immunoproteasome-selective inhibitors: the future of autoimmune diseases?
Chong Zhang, Huajian Zhu, Jiaan Shao, Ruoyu He, Jianjun Xi, Rangxiao Zhuang

Future Med Chem· February 2020

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Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases.
Jianjun Xi, Rangxiao Zhuang, Limin Kong, Ruoyu He, Huajian Zhu

Eur J Med Chem· November 2019

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Design, synthesis, and biological evaluation of novel 3-(thiophen-2-ylthio)pyridine derivatives as potential multitarget anticancer agents.
Jian-Jun Xi, Ruo-Yu He, Jian-Kang Zhang, Zhao-Bin Cai, Rang-Xiao Zhuang

Arch Pharm (Weinheim)· August 2019

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-diacetylcystine ameliorates inflammation in experimental non-alcoholic steatohepatitis by regulating nuclear transcription factor kappa B activation.
Fugen Wang, Shourong Liu, Rangxiao Zhuang, Jianfeng Bao, Yiqin Shen, Jianjun Xi

Int J Clin Exp Pathol· November 2018

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Activated carbon N-acetylcysteine microcapsule protects against nonalcoholic fatty liver disease in young rats via activating telomerase and inhibiting apoptosis.
Tingting Shi, Xingxin Yang, Hongping Zhou, Jianjun Xi, Jingjing Sun, Xiaojie Jiang, Rangxiao Zhuang

PLoS One· January 2018

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Identification of novel -acetylcysteine derivatives for the treatment of hepatocellular injury.
Shourong Liu, Yanmei Zhao, Ruoyu He, Limin Kong, Jianjun Xi, Rangxiao Zhuang

Medchemcomm· December 2017

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Stimulatory role of interleukin 10 in CD8 T cells through STATs in gastric cancer.
Jianjun Xi, Mingzheng Xu, Zongchang Song, Hongqiang Li, Shumin Xu

Tumour Biol· May 2017

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