Publications by authors named "Jiayuh Lin"

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IL-6 Blockade Enhances the Efficacy of CDK4/6 Inhibitor in -Mutant Triple-Negative Breast Cancer Cells.
Li Pan, Changyou Shi, Joungil Choi, Jiayuh Lin

Cells· October 2025

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Co-Inhibition of PARP and STAT3 as a Promising Approach for Triple-Negative Breast Cancer.
Changyou Shi, Li Pan, Satomi Amano, Mei-Yi Wu, Chenglong Li, Jiayuh Lin

Biomolecules· July 2025

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Synergistic effect of bazedoxifene and abemaciclib co‑treatment in triple‑negative breast cancer cells in vitro.
Kailey Caroland, Changyou Shi, Jiayuh Lin

Oncol Lett· December 2024

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Co-Inhibition of tGLI1 and GP130 Using FDA-Approved Ketoconazole and Bazedoxifene Is Synergistic Against the Growth and Metastasis of HER2-Enriched and Triple-Negative Breast Cancers.
Sara Manore, Chuling Zhuang, Mariana K Najjar, Grace L Wong, Shivani Bindal, Jiayuh Lin

Cells· December 2024

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Correction: Regua et al. TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers. 2021, , 2340.
Angelina T Regua, Noah R Aguayo, Sara Abu Jalboush, Daniel L Doheny, Sara G Manore, Jiayuh Lin

Cancers (Basel)· October 2024

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Bazedoxifene as a Potential Cancer Therapeutic Agent Targeting IL-6/GP130 Signaling.
Changyou Shi, Taylor Bopp, Hui-Wen Lo, Katherine Tkaczuk, Jiayuh Lin

Curr Oncol· September 2024

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Bazedoxifene Inhibits Cell Viability, Colony-Forming Activity, and Cell Migration in Human Non-Small Cell Lung Cancer Cells and Improves the Treatment Efficacy of Paclitaxel and Gemcitabine.
Yaochen Huang, Jiayuh Lin, Xiangning Fu, Lequn Li, Shenging Fu

Clin Respir J· August 2024

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Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
Daniel Doheny, Sherona Sirkisoon, Richard L Carpenter, Noah Reeve Aguayo, Angelina T Regua, Jiayuh Lin

Oncogene· June 2024

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Bazedoxifene Suppresses the Growth of Osteosarcoma Cells by Inhibiting IL-6 and IL-11/GP130 Signaling Pathway.
Xiaojuan Wu, Yang Cao, Hui Xiao, Jiexiong Feng, Jiayuh Lin

J Pediatr Hematol Oncol· January 2024

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CDK4/6 inhibitors in lung cancer: current practice and future directions.
Shuoshuo Lv, Jie Yang, Jiayuh Lin, Xiaoying Huang, Haiyang Zhao

Eur Respir Rev· January 2024

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Polarization of Cancer-Associated Macrophages Maneuver Neoplastic Attributes of Pancreatic Ductal Adenocarcinoma.
Huey-Jen Lin, Yingguang Liu, Kailey Caroland, Jiayuh Lin

Cancers (Basel)· July 2023

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Carbohydrate-Small Molecule Hybrids as Lead Compounds Targeting IL-6 Signaling.
Daniel C Schultz, Li Pan, Tiffany Wang, Conner Booker, Iram Hyder, Jiayuh Lin

Molecules· January 2023

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LLL12B, a Novel Small-Molecule STAT3 Inhibitor, Induces Apoptosis and Suppresses Cell Migration and Tumor Growth in Triple-Negative Breast Cancer Cells.
Li Pan, Xiang Chen, Feyruz Virgilia Rassool, Chenglong Li, Jiayuh Lin

Biomedicines· August 2022

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Combined inhibition of IL‑6 and IL‑8 pathways suppresses ovarian cancer cell viability and migration and tumor growth.
Ruijie Zhang, Dana M Roque, Jocelyn Reader, Jiayuh Lin

Int J Oncol· May 2022

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Breast Cancer Tumor Microenvironment and Molecular Aberrations Hijack Tumoricidal Immunity.
Huey-Jen Lin, Yingguang Liu, Denene Lofland, Jiayuh Lin

Cancers (Basel)· January 2022

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A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin.
Ruijie Zhang, Xiaozhi Yang, Dana M Roque, Chenglong Li, Jiayuh Lin

PLoS One· September 2021

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STAT3 inhibitor in combination with irradiation significantly inhibits cell viability, cell migration, invasion and tumorsphere growth of human medulloblastoma cells.
Li Pan, Ruijie Zhang, Ling Ma, Christopher R Pierson, Jonathan L Finlay, Jiayuh Lin

Cancer Biol Ther· September 2021

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Alleviation of Inflammation and Oxidative Stress in Pressure Overload-Induced Cardiac Remodeling and Heart Failure via IL-6/STAT3 Inhibition by Raloxifene.
Shengqi Huo, Wei Shi, Haiyan Ma, Dan Yan, Pengcheng Luo, Jiayuh Lin, Li Lin

Oxid Med Cell Longev· May 2021

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Synergistic Effect of Bazedoxifene and PARP Inhibitor in the Treatment of Ovarian Cancer Regardless of BRCA Mutation.
Ruijie Zhang, Tiffany Wang, Jiayuh Lin

Anticancer Res· May 2021

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TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers.
Angelina T Regua, Noah R Aguayo, Sara Abu Jalboush, Daniel L Doheny, Sara G Manore, Jiayuh Lin

Cancers (Basel)· May 2021

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Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment.
Sherona R Sirkisoon, Richard L Carpenter, Tadas Rimkus, Daniel Doheny, Dongqin Zhu, Linda J Metheny-Barlow, Jiayuh Lin, Angelina T Regua

Oncogene· March 2021

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LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cells.
Xiang Chen, Li Pan, Jia Wei, Ruijie Zhang, Xiaozhi Yang, Shengling Fu, Jiayuh Lin

Sci Rep· March 2021

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Bazedoxifene exhibits anti-inflammation and anti-atherosclerotic effects via inhibition of IL-6/IL-6R/STAT3 signaling.
Pengcheng Luo, Yina Wang, Chongqiang Zhao, Junyi Guo, Wei Shi, Jiayuh Lin, Li Lin

Eur J Pharmacol· February 2021

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Raloxifene inhibits IL-6/STAT3 signaling pathway and protects against high-fat-induced atherosclerosis in ApoE mice.
Pengcheng Luo, Wei Shi, Yina Wang, Haiyan Ma, Tianshu Liu, Jiayuh Lin, Li Lin

Life Sci· November 2020

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Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
Daniel Doheny, Sherona Sirkisoon, Richard L Carpenter, Noah Reeve Aguayo, Angelina T Regua, Jiayuh Lin

Oncogene· October 2020

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