Publications by authors named "Jim Eyles"

Claim this Profile
A
An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine release.
Miguel Gaspar, Marina Natoli, Laure Castan, Sharif Rahmy, Martin Korade, Jim Eyles

J Immunother Cancer· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Intratumoral IL12 mRNA administration activates innate and adaptive pathways in checkpoint inhibitor-resistant tumors resulting in complete responses.
Jayalakshmi Lakshmipathi, Sreevidya Santha, Man Li, Yuping Qian, Simon F Roy, Jim Eyles

Cancer Immunol Immunother· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Blocking LIF and PD-L1 enhances the antitumor efficacy of SBRT in murine PDAC models.
Jian Ye, Shuyang S Qin, Angela L Hughson, Gary Hannon, Noah A Salama, Jim Eyles

J Immunother Cancer· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Intratumoral IL12 mRNA administration activates innate and adaptive pathways in checkpoint inhibitor resistant tumors resulting in complete responses.
Jayalakshmi Lakshmipathi, Sreevidya Santha, Man Li, Yuping Qian, Simon F Roy, Jim Eyles

Res Sq· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Blockade of LIF and PD-L1 Enhances Chemotherapy in Preclinical PDAC Models.
Jian Ye, Shuyang S Qin, Angela L Hughson, Gary Hannon, Tara G Vrooman, Jim Eyles

Cancers (Basel)· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models.
Brajesh P Kaistha, Gozde Kar, Andreas Dannhorn, Amanda Watkins, Grace Opoku-Ansah, Jim Eyles

Cancer Biol Ther· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A mechanistic PK/PD model of AZD0171 (anti-LIF) to support Phase II dose selection.
Azar Shahraz, Mark Penney, Juliana Candido, Grace Opoku-Ansah, Melanie Neubauer, Jim Eyles

CPT Pharmacometrics Syst Pharmacol· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Bayesian modeling for analyzing heterogeneous response in preclinical mouse tumor models.
Bairu Zhang, Lukasz Magiera, Juliana Candido, Olga Muraeva, Jane Coates Ulrichsen, Jim Eyles

Sci Transl Med· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CD73 controls Myosin II-driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells.
Remi Samain, Oscar Maiques, Joanne Monger, Hoyin Lam, Juliana Candido, Jim Eyles

Sci Adv· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
Vincenzo Graziano, Andreas Dannhorn, Heather Hulme, Kate Williamson, Hannah Buckley, Jim Eyles

J Immunother Cancer· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CD73 and PD-L1 dual blockade amplifies antitumor efficacy of SBRT in murine PDAC models.
Jian Ye, Nicholas W Gavras, David C Keeley, Angela L Hughson, Gary Hannon, Jim Eyles

J Immunother Cancer· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Recombinant Newcastle Disease Virus Immunotherapy Drives Oncolytic Effects and Durable Systemic Antitumor Immunity.
James Harper, Shannon Burke, Jon Travers, Nicola Rath, Andrew Leinster, Jim Eyles

Mol Cancer Ther· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vivo screen of genetically conserved Streptococcus pneumoniae proteins for protective immunogenicity.
Richard J Anderson, Siradanahalli Guru, Risini Weeratna, Shawn Makinen, Derek J Falconer, Jim E Eyles

Vaccine· December 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nonreplicating vaccines can protect african green monkeys from the memphis 37 strain of respiratory syncytial virus.
Jim E Eyles, J Erik Johnson, Shakuntala Megati, Vidia Roopchand, Paul J Cockle

J Infect Dis· July 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The efficacy of HSV-2 vaccines based on gD and gB is enhanced by the addition of ICP27.
Helen Bright, David Lucia Perez, Clare Christy, Paul Cockle, Jim E Eyles

Vaccine· December 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Immunogenicity and efficacy of an anthrax/plague DNA fusion vaccine in a mouse model.
Mark T Albrecht, Jim E Eyles, Les W Baillie, Andrea M Keane-Myers

FEMS Immunol Med Microbiol· August 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Peripheral human γδ T cells control growth of both avirulent and highly virulent strains of Francisella tularensis in vitro.
Caroline A Rowland, M Gill Hartley, Helen Flick-Smith, Thomas R Laws, Jim E Eyles

Microbes Infect· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Single and combination herpes simplex virus type 2 glycoprotein vaccines adjuvanted with CpG oligodeoxynucleotides or monophosphoryl lipid A exhibit differential immunity that is not correlated to protection in animal models.
Tansi Khodai, Debbie Chappell, Clare Christy, Paul Cockle, Jim Eyles

Clin Vaccine Immunol· October 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Deletion of the Bacillus anthracis capB homologue in Francisella tularensis subspecies tularensis generates an attenuated strain that protects mice against virulent tularaemia.
Stephen L Michell, Rachel E Dean, Jim E Eyles, Margaret Gill Hartley, Emma Waters

J Med Microbiol· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Concomitant administration of Yersinia pestis specific monoclonal antibodies with plague vaccine has a detrimental effect on vaccine mediated immunity.
Jim E Eyles, Wendy A Butcher, Richard W Titball, Jim Hill

Vaccine· October 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Therapeutic use of molecules that mimic pathogen danger signals.
Jim E Eyles

Endocr Metab Immune Disord Drug Targets· September 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Immunodominant Francisella tularensis antigens identified using proteome microarray.
Jim E Eyles, Berkay Unal, Margaret Gill Hartley, Sarah L Newstead, Helen Flick-Smith

Proteomics· June 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Administration of antibody to the lung protects mice against pneumonic plague.
Jim Hill, Jim E Eyles, Stephen J Elvin, Gareth D Healey, Roman A Lukaszewski

Infect Immun· May 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Immunological responses after immunisation of mice with microparticles containing antigen and single stranded RNA (polyuridylic acid).
Angie Westwood, Stephen J Elvin, Gareth D Healey, E Diane Williamson, Jim E Eyles

Vaccine· March 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Particulate delivery systems for biodefense subunit vaccines.
Vincent W Bramwell, Jim E Eyles, H Oya Alpar

Adv Drug Deliv Rev· June 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis