Publications by authors named "Jim Sun"

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Vacuolar-ATPase inhibitors are antimicrobial agents active against intracellular mycobacteria.
Leah Rankine-Wilson, Tirosh Shapira, Jake Felker, Matthew Christofferson, Henok Sahile, Jim Sun

Antimicrob Agents Chemother· December 2025

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Growth inhibition of Saccharomyces cerevisiae by SUMO-specific nanobodies.
Pavana Suresh, Sun Zhen-Yu Jim, Ishani Sahay, Allison Y Tang, Charlotte Wijne

Sci Rep· May 2025

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Discovery of benzo[c]phenanthridine derivatives with potent activity against multidrug-resistant .
Yi Chu Liang, Zhiqi Sun, Chen Lu, Andréanne Lupien, Zhongliang Xu, Jim Sun

Microbiol Spectr· November 2024

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Small Molecule Targeting PPM1A Activates Autophagy for Host-Directed Therapy.
Zhipeng Yu, Yi Chu Liang, Stefania Berton, Liping Liu, Jiaqi Zou, Jim Sun

J Med Chem· July 2024

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ATF2 orchestrates macrophage differentiation and activation to promote antibacterial responses.
Nusrah Rajabalee, Hannah Siushansian, Milani Weerapura, Stefania Berton, Fjolla Berbatovci, Jim Sun

J Leukoc Biol· September 2023

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infection triggers epigenetic changes that are enriched in a type I IFN signature.
Katrina Madden, Rayan El Hamra, Stefania Berton, Jake Felker, Gonzalo G Alvarez, Jim Sun

Microlife· February 2023

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An biosafety-level-2-compatible model of infection for drug susceptibility testing.
Yi Chu Liang, Stefania Berton, Courtney Reeks, Jim Sun

STAR Protoc· September 2022

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TREM2 Promotes Immune Evasion by Mycobacterium tuberculosis in Human Macrophages.
Ankita Dabla, Yi Chu Liang, Nusrah Rajabalee, Courtney Irwin, Carolyn G J Moonen, Jim Sun

mBio· August 2022

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A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis.
Stefania Berton, Lu Chen, Yi Chu Liang, Zhongliang Xu, Afrakoma Afriyie-Asante, Jim Sun

Cell Chem Biol· July 2022

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Surveying the Epigenetic Landscape of Tuberculosis in Alveolar Macrophages.
Katrina Madden, Yi Chu Liang, Nusrah Rajabalee, Gonzalo G Alvarez, Jim Sun

Infect Immun· May 2022

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Protein Kinase R in Bacterial Infections: Friend or Foe?
Robin Smyth, Jim Sun

Front Immunol· December 2021

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Exploits Focal Adhesion Kinase to Induce Necrotic Cell Death and Inhibit Reactive Oxygen Species Production.
Afrakoma Afriyie-Asante, Ankita Dabla, Amy Dagenais, Stefania Berton, Robin Smyth, Jim Sun

Front Immunol· December 2021

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Protein Kinase R Restricts the Intracellular Survival of by Promoting Selective Autophagy.
Robin Smyth, Stefania Berton, Nusrah Rajabalee, Therese Chan, Jim Sun

Front Microbiol· January 2021

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Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7.
Evida A Dennis, Lesley E Smythies, Robert Grabski, Mao Li, Mary E Ballestas, Jim J Sun

Mucosal Immunol· November 2018

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NAD Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis.
David Pajuelo, Norberto Gonzalez-Juarbe, Uday Tak, Jim Sun, Carlos J Orihuela

Cell Rep· July 2018

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The phosphatase PPM1A controls monocyte-to-macrophage differentiation.
Samuel R Smith, Kaitlyn Schaaf, Nusrah Rajabalee, Frederic Wagner, Alexandra Duverger, Jim Sun

Sci Rep· January 2018

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A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis.
Kaitlyn Schaaf, Samuel R Smith, Virginia Hayley, Olaf Kutsch, Jim Sun

J Vis Exp· March 2017

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Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis.
Kaitlyn Schaaf, Samuel R Smith, Alexandra Duverger, Frederic Wagner, Frank Wolschendorf, Jim Sun

Sci Rep· February 2017

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8-Hydroxyquinolines Are Boosting Agents of Copper-Related Toxicity in Mycobacterium tuberculosis.
Santosh Shah, Alex G Dalecki, Aruni P Malalasekera, Cameron L Crawford, Suzanne M Michalek, Jim Sun

Antimicrob Agents Chemother· October 2016

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A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis.
Kaitlyn Schaaf, Virginia Hayley, Alexander Speer, Frank Wolschendorf, Michael Niederweis, Jim Sun

Assay Drug Dev Technol· August 2016

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Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection.
Jim Sun, Kaitlyn Schaaf, Alexandra Duverger, Frank Wolschendorf, Alexander Speer

Oncotarget· March 2016

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Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages.
Alexander Speer, Jim Sun, Olga Danilchanka, Virginia Meikle, Jennifer L Rowland

Mol Microbiol· September 2015

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The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD.
Jim Sun, Axel Siroy, Ravi K Lokareddy, Alexander Speer, Kathryn S Doornbos

Nat Struct Mol Biol· September 2015

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An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.
Olga Danilchanka, Jim Sun, Mikhail Pavlenok, Christian Maueröder, Alexander Speer

Proc Natl Acad Sci U S A· May 2014

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Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity.
Jim Sun, Vijender Singh, Alice Lau, Richard W Stokes, Andrés Obregón-Henao

PLoS Pathog· February 2014

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