Publications by authors named "Jim Swildens"

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QR-1011 restores defective ABCA4 splicing caused by multiple severe ABCA4 variants underlying Stargardt disease.
Melita Kaltak, Petra de Bruijn, Willemijn van Leeuwen, Gerard Platenburg, Frans P M Cremers, Jim Swildens

Sci Rep· January 2024

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Stargardt disease-associated missense and synonymous ABCA4 variants result in aberrant splicing.
Melita Kaltak, Zelia Corradi, Rob W J Collin, Jim Swildens, Frans P M Cremers

Hum Mol Genet· October 2023

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Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function.
Melita Kaltak, Rocio Blanco-Garavito, Laurie L Molday, Claire-Marie Dhaenens, Eric E Souied, Jim Swildens

J Transl Med· August 2023

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Antisense oligonucleotide therapy corrects splicing in the common Stargardt disease type 1-causing variant c.5461-10T>C.
Melita Kaltak, Petra de Bruijn, Davide Piccolo, Sang-Eun Lee, Kalyan Dulla, Jim Swildens

Mol Ther Nucleic Acids· March 2023

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QR-313, an Antisense Oligonucleotide, Shows Therapeutic Efficacy for Treatment of Dominant and Recessive Dystrophic Epidermolysis Bullosa: A Preclinical Study.
Olivier Bornert, Marieke Hogervorst, Pauline Nauroy, Johannes Bischof, Jim Swildens

J Invest Dermatol· April 2021

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Evaluation of eluforsen, a novel RNA oligonucleotide for restoration of CFTR function in in vitro and murine models of p.Phe508del cystic fibrosis.
Wouter Beumer, Jim Swildens, Teresinha Leal, Sabrina Noel, Herma Anthonijsz

PLoS One· February 2020

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Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype.
Eric P van der Veer, Ruben G de Bruin, Adriaan O Kraaijeveld, Margreet R de Vries, Ilze Bot, Jim Swildens

Circ Res· October 2013

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Generation of Helper Plasmids Encoding Mutant Adeno-associated Virus Type 2 Capsid Proteins with Increased Resistance against Proteasomal Degradation.
Naghmeh Ahmadiankia, Vajiheh Neshati, Zeinab Neshati, Jim Swildens, Antoine Af de Vries

Iran J Basic Med Sci· July 2013

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Similar arrhythmicity in hypertrophic and fibrotic cardiac cultures caused by distinct substrate-specific mechanisms.
Saïd F A Askar, Brian O Bingen, Martin J Schalij, Jim Swildens, Douwe E Atsma

Cardiovasc Res· January 2013

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Gap junctional coupling with cardiomyocytes is necessary but not sufficient for cardiomyogenic differentiation of cocultured human mesenchymal stem cells.
Arti A Ramkisoensing, Daniël A Pijnappels, Jim Swildens, Marie José Goumans, Willem E Fibbe

Stem Cells· June 2012

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Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterparts.
Arti A Ramkisoensing, Daniël A Pijnappels, Saïd F A Askar, Robert Passier, Jim Swildens

PLoS One· March 2012

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Connexin43 silencing in myofibroblasts prevents arrhythmias in myocardial cultures: role of maximal diastolic potential.
Saïd F Askar, Brian O Bingen, Jim Swildens, Dirk L Ypey, Arnoud van der Laarse

Cardiovasc Res· March 2012

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Antiproliferative treatment of myofibroblasts prevents arrhythmias in vitro by limiting myofibroblast-induced depolarization.
Saïd F A Askar, Arti A Ramkisoensing, Martin J Schalij, Brian O Bingen, Jim Swildens

Cardiovasc Res· May 2011

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Integrin stimulation favors uptake of macromolecules by cardiomyocytes in vitro.
Jim Swildens, Antoine A F de Vries, Zhongyan Li, Soban Umar, Douwe E Atsma

Cell Physiol Biochem· April 2011

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Genetic complementation of human muscle cells via directed stem cell fusion.
Manuel A F V Gonçalves, Jim Swildens, Maarten Holkers, Anjali Narain, Gijsbert P van Nierop

Mol Ther· April 2008

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