Publications by authors named "Wouter Beumer"

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Antisense oligonucleotide therapy corrects splicing in the common Stargardt disease type 1-causing variant c.5461-10T>C.
Melita Kaltak, Petra de Bruijn, Davide Piccolo, Sang-Eun Lee, Kalyan Dulla, Wouter Beumer

Mol Ther Nucleic Acids· March 2023

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A pathogenic proteolysis-resistant huntingtin isoform induced by an antisense oligonucleotide maintains huntingtin function.
Hyeongju Kim, Sophie Lenoir, Angela Helfricht, Taeyang Jung, Zhana K Karneva, Wouter Beumer

JCI Insight· September 2022

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Animal models for cystic fibrosis: a systematic search and mapping review of the literature. Part 2: nongenetic models.
Cathalijn Hc Leenaars, Rob Bm de Vries, Joey Reijmer, David Holthaus, Damian Visser, Wouter Beumer

Lab Anim· August 2021

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Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations.
Kalyan Dulla, Ralph Slijkerman, Hester C van Diepen, Silvia Albert, Margo Dona, Wouter Beumer

Mol Ther· August 2021

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Animal models for cystic fibrosis: A systematic search and mapping review of the literature - Part 1: genetic models.
Cathalijn Hc Leenaars, Rob Bm De Vries, Anna Heming, Damian Visser, David Holthaus, Wouter Beumer

Lab Anim· August 2020

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Improving Translation by Identifying Evidence for More Human-Relevant Preclinical Strategies.
Merel Ritskes-Hoitinga, Cathalijn Leenaars, Wouter Beumer, Tineke Coenen-de Roo, Frans Stafleu

Animals (Basel)· July 2020

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Evaluation of eluforsen, a novel RNA oligonucleotide for restoration of CFTR function in in vitro and murine models of p.Phe508del cystic fibrosis.
Wouter Beumer, Jim Swildens, Teresinha Leal, Sabrina Noel, Herma Anthonijsz

PLoS One· February 2020

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The Cystic Fibrosis-Like Airway Surface Layer Is not a Significant Barrier for Delivery of Eluforsen to Airway Epithelial Cells.
Vera Brinks, Katarzyna Lipinska, Miranda de Jager, Wouter Beumer, Brian Button

J Aerosol Med Pulm Drug Deliv· October 2019

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Splice-Modulating Oligonucleotide QR-110 Restores CEP290 mRNA and Function in Human c.2991+1655A>G LCA10 Models.
Kalyan Dulla, Monica Aguila, Amelia Lane, Katarina Jovanovic, David A Parfitt, Wouter Beumer

Mol Ther Nucleic Acids· September 2018

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Exaggerated Increases in Microglia Proliferation, Brain Inflammatory Response and Sickness Behaviour upon Lipopolysaccharide Stimulation in Non-Obese Diabetic Mice.
Barry McGuiness, Sinead M Gibney, Wouter Beumer, Marjan A Versnel, Inge Sillaber

Neuroimmunomodulation· April 2018

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Contrasting expression pattern of RNA-sensing receptors TLR7, RIG-I and MDA5 in interferon-positive and interferon-negative patients with primary Sjögren's syndrome.
Naomi I Maria, Eline C Steenwijk, Arne S IJpma, Cornelia G van Helden-Meeuwsen, Petra Vogelsang, Wouter Beumer

Ann Rheum Dis· April 2017

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The gene expression profile of CD11c+ CD8α- dendritic cells in the pre-diabetic pancreas of the NOD mouse.
Wouter Beumer, Jojanneke M C Welzen-Coppens, Cornelia G van Helden-Meeuwsen, Sinead M Gibney, Hemmo A Drexhage

PLoS One· October 2015

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Microglia shape corpus callosum axon tract fasciculation: functional impact of prenatal inflammation.
Lorena Pont-Lezica, Wouter Beumer, Sabrina Colasse, Hemmo Drexhage, Marjan Versnel

Eur J Neurosci· May 2014

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Changes in serum adhesion molecules, chemokines, cytokines, and tissue remodeling factors in euthyroid women without thyroid antibodies who are at risk for autoimmune thyroid disease: a hypothesis on the early phases of the endocrine autoimmune reaction.
Wouter Beumer, Grigoris Effraimidis, Roosmarijn C Drexhage, Wilmar M Wiersinga, Hemmo A Drexhage

J Clin Endocrinol Metab· June 2013

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Prevalence of interferon type I signature in CD14 monocytes of patients with Sjogren's syndrome and association with disease activity and BAFF gene expression.
Zana Brkic, Naomi I Maria, Cornelia G van Helden-Meeuwsen, Joop P van de Merwe, Paul L van Daele, Wouter Beumer

Ann Rheum Dis· May 2013

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Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome.
Wouter Beumer, Roosmarijn C Drexhage, Harm De Wit, Marjan A Versnel, Hemmo A Drexhage

Psychoneuroendocrinology· December 2012

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The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes.
Wouter Beumer, Sinead M Gibney, Roosmarijn C Drexhage, Lorena Pont-Lezica, Janine Doorduin

J Leukoc Biol· November 2012

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The mononuclear phagocyte system and its cytokine inflammatory networks in schizophrenia and bipolar disorder.
Roosmarijn C Drexhage, Esther M Knijff, Roos C Padmos, Leonie van der Heul-Nieuwenhuijzen, Wouter Beumer

Expert Rev Neurother· January 2010

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