Publications by authors named "Jimmy X Tang"

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A novel antagonist of Toll-like receptors 7, 8 and 9 suppresses lupus disease-associated parameters in NZBW/F1 mice.
Fu-Gang Zhu, Weiwen Jiang, Lakshmi Bhagat, Daqing Wang, Dong Yu, Jimmy X Tang

Autoimmunity· November 2013

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A Toll-like receptor 7, 8, and 9 antagonist inhibits Th1 and Th17 responses and inflammasome activation in a model of IL-23-induced psoriasis.
Weiwen Jiang, Fu-Gang Zhu, Lakshmi Bhagat, Dong Yu, Jimmy X Tang

J Invest Dermatol· July 2013

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Design of synthetic oligoribonucleotide-based agonists of Toll-like receptor 3 and their immune response profiles in vitro and in vivo.
Tao Lan, Daqing Wang, Lakshmi Bhagat, Victoria J Philbin, Dong Yu, Jimmy X Tang

Org Biomol Chem· February 2013

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Novel oligonucleotides containing two 3'-ends complementary to target mRNA show optimal gene-silencing activity.
Lakshmi Bhagat, Mallikarjuna Reddy Putta, Daqing Wang, Dong Yu, Tao Lan, Jimmy X Tang

J Med Chem· April 2011

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Synthesis and immunological activities of novel agonists of toll-like receptor 9.
Mary Struthers, Andrew J Bett, Thomas Wisniewski, Sheri A Dubey, Melissa Precopio, Jimmy X Tang

Cell Immunol· August 2010

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Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8.
Daqing Wang, Melissa Precopio, Tao Lan, Dong Yu, Jimmy X Tang

Mol Cancer Ther· June 2010

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Oligodeoxyribonucleotide-based antagonists for Toll-like receptors 7 and 9.
Daqing Wang, Lakshmi Bhagat, Dong Yu, Fu-Gang Zhu, Jimmy X Tang

J Med Chem· January 2009

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Agonists of Toll-like receptor 9 containing synthetic dinucleotide motifs.
Dong Yu, Mallikarjuna R Putta, Lakshmi Bhagat, Yukui Li, Fugang Zhu, Jimmy X Tang

J Med Chem· December 2007

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Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8.
Tao Lan, Ekambar R Kandimalla, Dong Yu, Lakshmi Bhagat, Yukui Li, Jimmy X Tang

Proc Natl Acad Sci U S A· August 2007

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Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.
Ekambar R Kandimalla, Lakshmi Bhagat, Yukui Li, Dong Yu, Daqing Wang, Jimmy X Tang

Proc Natl Acad Sci U S A· May 2005

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Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity.
Daqing Wang, Ekambar R Kandimalla, Dong Yu, Jimmy X Tang, Sudhir Agrawal

Vaccine· April 2005

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Modulation of ovalbumin-induced Th2 responses by second-generation immunomodulatory oligonucleotides in mice.
Fu-Gang Zhu, Ekambar R Kandimalla, Dong Yu, Jimmy X Tang, Sudhir Agrawal

Int Immunopharmacol· July 2004

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A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif.
Ekambar R Kandimalla, Lakshmi Bhagat, Fu-Gang Zhu, Dong Yu, Yan-Ping Cong, Jimmy X Tang, Jin-Yan Tang

Proc Natl Acad Sci U S A· November 2003

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