Publications by authors named "Jody Vykoukal"

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Lung adenocarcinoma surfaceome remodeling with EGFR inhibitors uncovers placental alkaline phosphatase as a target for combination therapy.
Yihui Chen, Rongzhang Dou, Monica J Hong, Hanwen Xu, Jody Vykoukal

Cell Rep Med· December 2025

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Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer.
Jody Vykoukal, Yihui Chen, Mingxin Zuo, Riccardo Ballarò, Monica J Hong

Cell Rep Med· December 2025

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Validation of a blood test for multi-cancer risk stratification in a lung cancer screening cohort.
Johannes F Fahrmann, Ehsan Irajizad, Hamid Rudsari, Jody Vykoukal, Iakovos Toumazis

medRxiv· November 2025

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Protocol for isolating patient-derived ascites cells and extracellular vesicles from gastric cancer peritoneal metastases.
Yibo Fan, Jody V Vykoukal, Shumei Song, Melissa Pool Pizzi, Gengyi Zou

STAR Protoc· October 2025

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Long-chain sulfatide enrichment is an actionable metabolic vulnerability in intraductal papillary mucinous neoplasm (IPMN)-associated pancreatic cancers.
Yihui Chen, Riccardo Ballarò, Marta Sans, Fredrik Ivar Thege, Mingxin Zuo, Jody Vykoukal

Gut· September 2025

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KAP1 promotes gastric adenocarcinoma progression by activating Hippo/YAP1 signaling via binding to HNRNPAB.
Shumei Song, Yibo Fan, Gengyi Zou, Longfei Huo, Janani Kumar, Jody V Vykoukal

Cancer Lett· July 2025

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Integrated Metabolomics and Spatial Transcriptomics of Cystic Pancreatic Cancer Precursors Reveals Dysregulated Polyamine Metabolism as a Biomarker of Progression.
Ricardo A León-Letelier, Yihui Chen, Rongzhang Dou, Ehsan Irajizad, Michele T Yip-Schneider, Jody Vykoukal

Clin Cancer Res· June 2025

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Citrullinated ENO1 Vaccine Enhances PD-1 Blockade in Mice Implanted with Murine Triple-Negative Breast Cancer Cells.
Ricardo A León-Letelier, Alejandro M Sevillano-Mantas, Yihui Chen, Soyoung Park, Jody Vykoukal

Vaccines (Basel)· June 2025

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Grape-Pi: graph-based neural networks for enhanced protein identification in proteomics pipelines.
Chunhui Gu, Seyyed Mahmood Ghasemi, Yining Cai, Johannes F Fahrmann, James P Long, Jody Vykoukal

Bioinform Adv· April 2025

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Lead time trajectory of blood-based protein biomarkers for detection of pancreatic cancer based on repeat testing.
Johannes F Fahrmann, Michele Yip-Schneider, Jody Vykoukal, Rachelle Spencer, Jennifer B Dennison

Cancer Lett· March 2025

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Exosomal Galectin-3 promotes peritoneal metastases in gastric adenocarcinoma via microenvironment alterations.
Yibo Fan, Shumei Song, Melissa Pool Pizzi, Gengyi Zou, Jody V Vykoukal

iScience· January 2025

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Biomarker trajectory for earlier detection of lung cancer.
Ehsan Irajizad, Johannes F Fahrmann, Iakovos Toumazis, Jody Vykoukal, Jennifer B Dennison

EBioMedicine· October 2024

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A metabolite-based liquid biopsy for detection of ovarian cancer.
Johannes F Fahrmann, Seyyed Mahmood Ghasemi, Chae Y Han, Ranran Wu, Jennifer B Dennison, Jody Vykoukal

Biomark Res· August 2024

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Validation of a Blood-Based Protein Biomarker Panel for a Risk Assessment of Lethal Lung Cancer in the Physicians' Health Study.
Lulu Song, Ehsan Irajizad, Andrew Rundle, Howard D Sesso, John Michael Gaziano, Jody V Vykoukal

Cancers (Basel)· May 2024

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Contributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer.
Ricardo A León-Letelier, Rongzhang Dou, Jody Vykoukal, Michele T Yip-Schneider, Anirban Maitra

Clin Chem· January 2024

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Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: insights from the BE GONE trial.
Xiaotao Zhang, Ehsan Irajizad, Kristi L Hoffman, Johannes F Fahrmann, Fangyu Li, Jody Vykoukal

EBioMedicine· December 2023

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Blood-based Proteomic Signatures Associated With MEN1-related Duodenopancreatic Neuroendocrine Tumor Progression.
Johannes F Fahrmann, Amanda R Wasylishen, Carolina R C Pieterman, Ehsan Irajizad, Jody Vykoukal

J Clin Endocrinol Metab· November 2023

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SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor-Induced Growth Suppression.
Chuandong Geng, Man-Chao Zhang, Ganiraju C Manyam, Jody V Vykoukal, Johannes F Fahrmann

Clin Cancer Res· November 2023

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The kynurenine pathway presents multi-faceted metabolic vulnerabilities in cancer.
Ricardo A León-Letelier, Rongzhang Dou, Jody Vykoukal, Ali Hussein Abdel Sater, Edwin Ostrin

Front Oncol· October 2023

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Mortality Benefit of a Blood-Based Biomarker Panel for Lung Cancer on the Basis of the Prostate, Lung, Colorectal, and Ovarian Cohort.
Ehsan Irajizad, Johannes F Fahrmann, Tracey Marsh, Jody Vykoukal, Jennifer B Dennison

J Clin Oncol· September 2023

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A blood-based metabolomic signature predictive of risk for pancreatic cancer.
Ehsan Irajizad, Ana Kenney, Tiffany Tang, Jody Vykoukal, Ranran Wu

Cell Rep Med· September 2023

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Integrated spatial transcriptomics and lipidomics of precursor lesions of pancreatic cancer identifies enrichment of long chain sulfatide biosynthesis as an early metabolic alteration.
Marta Sans, Yihui Chen, Fredrik I Thege, Rongzhang Dou, Jimin Min, Jody Vykoukal

bioRxiv· August 2023

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Low-density lipoprotein electronegativity and risk of death after acute coronary syndromes: A case-cohort analysis.
Simon Kraler, Florian A Wenzl, Jody Vykoukal, Johannes F Fahrmann, Ming-Yi Shen

Atherosclerosis· July 2023

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Proteogenomic landscape of gastric adenocarcinoma peritoneal metastases.
Shuangtao Zhao, Ruiping Wang, Shumei Song, Dapeng Hao, Guangchun Han, Jody Vykoukal

iScience· June 2023

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Kynureninase Upregulation Is a Prominent Feature of NFR2-Activated Cancers and Is Associated with Tumor Immunosuppression and Poor Prognosis.
Ricardo A León-Letelier, Ali H Abdel Sater, Yihui Chen, Soyoung Park, Ranran Wu, Jody V Vykoukal

Cancers (Basel)· January 2023

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