Publications by authors named "Joely Irlam"

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Randomized Phase 3 Trial of the Hypoxia Modifier Nimorazole Added to Radiation Therapy With Benefit Assessed in Hypoxic Head and Neck Cancers Determined Using a Gene Signature (NIMRAD).
David J Thomson, Nick J Slevin, Helen Baines, Guy Betts, Steve Bolton, Joely Irlam

Int J Radiat Oncol Biol Phys· July 2024

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Digital spatial profiling of the microenvironment of muscle invasive bladder cancer.
Michael Eyers, Joely Irlam, Gayle Marshall, Vicky Smith, Alexander Baker

Commun Biol· June 2024

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Technical development and validation of a clinically applicable microenvironment classifier as a biomarker of tumour hypoxia for soft tissue sarcoma.
Laura J Forker, Becky Bibby, Lingjian Yang, Brian Lane, Joely Irlam

Br J Cancer· June 2023

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Long-Term Outcomes of Radical Radiation Therapy with Hypoxia Modification with Biomarker Discovery for Stratification: 10-Year Update of the BCON (Bladder Carbogen Nicotinamide) Phase 3 Randomized Trial (ISRCTN45938399).
Yee Pei Song, Hitesh Mistry, Joely Irlam, Helen Valentine, Lingjian Yang

Int J Radiat Oncol Biol Phys· August 2021

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Correction: Validation of a hypoxia related gene signature in multiple soft tissue sarcoma cohorts.
Lingjian Yang, Laura Forker, Joely J Irlam, Nischalan Pillay, Ananya Choudhury

Oncotarget· March 2019

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Mapping Hypoxia in Renal Carcinoma with Oxygen-enhanced MRI: Comparison with Intrinsic Susceptibility MRI and Pathology.
Ross A Little, Yann Jamin, Jessica K R Boult, Josephine H Naish, Yvonne Watson, Joely Irlam

Radiology· September 2018

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The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma.
Laura Forker, Piers Gaunt, Stefano Sioletic, Patrick Shenjere, Robert Potter, Joely Irlam

Br J Cancer· March 2018

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Validation of a hypoxia related gene signature in multiple soft tissue sarcoma cohorts.
Lingjian Yang, Laura Forker, Joely J Irlam, Nischalan Pillay, Ananya Choudhury

Oncotarget· January 2018

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A Gene Signature for Selecting Benefit from Hypoxia Modification of Radiotherapy for High-Risk Bladder Cancer Patients.
Lingjian Yang, Janet Taylor, Amanda Eustace, Joely J Irlam, Helen Denley

Clin Cancer Res· August 2017

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Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas.
Natalie Burrows, Joseph Williams, Brian A Telfer, Julia Resch, Helen R Valentine, Joely Irlam

Oncotarget· September 2016

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A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer.
Amanda Eustace, Navin Mani, Paul N Span, Joely J Irlam, Janet Taylor

Clin Cancer Res· September 2013

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Necrosis predicts benefit from hypoxia-modifying therapy in patients with high risk bladder cancer enrolled in a phase III randomised trial.
Amanda Eustace, Joely J Irlam, Janet Taylor, Helen Denley, Shailesh Agrawal

Radiother Oncol· July 2013

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Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma.
Guy N J Betts, Amanda Eustace, Shalini Patiar, Helen R Valentine, Joely Irlam

Eur J Cancer· January 2013

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The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens.
Ryan D Guest, Robert E Hawkins, Natalia Kirillova, Eleanor J Cheadle, Jennifer Arnold, Joely Irlam

J Immunother· October 2005

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Gene therapy of patient-derived T lymphocytes to target and eradicate colorectal hepatic metastases.
Aali J Sheen, Joely Irlam, Natalia Kirillova, Ryan D Guest, David J Sherlock

Dis Colon Rectum· June 2003

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