Publications by authors named "Ryan D Guest"

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Clinical feasibility and treatment outcomes with nonselected autologous tumor-infiltrating lymphocyte therapy in patients with advanced cutaneous melanoma.
Manon Pillai, Yizhou Jiang, Paul C Lorigan, Fiona C Thistlethwaite, Martine Thomas, Ryan D Guest

Am J Cancer Res· August 2022

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The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity.
Fiona C Thistlethwaite, David E Gilham, Ryan D Guest, Dominic G Rothwell, Manon Pillai

Cancer Immunol Immunother· November 2017

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Definition and application of good manufacturing process-compliant production of CEA-specific chimeric antigen receptor expressing T-cells for phase I/II clinical trial.
Ryan D Guest, Natalia Kirillova, Sam Mowbray, Hannah Gornall, Dominic G Rothwell

Cancer Immunol Immunother· February 2014

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The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens.
Ryan D Guest, Robert E Hawkins, Natalia Kirillova, Eleanor J Cheadle, Jennifer Arnold

J Immunother· October 2005

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Gene therapy of patient-derived T lymphocytes to target and eradicate colorectal hepatic metastases.
Aali J Sheen, Joely Irlam, Natalia Kirillova, Ryan D Guest, David J Sherlock

Dis Colon Rectum· June 2003

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Primary polyclonal human T lymphocytes targeted to carcino-embryonic antigens and neural cell adhesion molecule tumor antigens by CD3zeta-based chimeric immune receptors.
David E Gilham, Allison O'Neil, Chris Hughes, Ryan D Guest, Natalia Kirillova

J Immunother· October 2002

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