Publications by authors named "Johan Schultz"

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A Small Molecule Antagonist of CX3CR1 (KAND567) Inhibited the Tumor Growth-Promoting Effect of Monocytes in Chronic Lymphocytic Leukemia (CLL).
Wen Zhong, Parviz Kokhaei, Tom A Mulder, Amineh Ghaderi, Ali Moshfegh, Johan Schultz

Cancers (Basel)· November 2024

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A Small Molecule Targeting the Intracellular Tyrosine Kinase Domain of ROR1 (KAN0441571C) Induced Significant Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells.
Amineh Ghaderi, Mohammad-Ali Okhovat, Jemina Lehto, Luigi De Petris, Ehsan Manouchehri Doulabi, Johan Schultz

Pharmaceutics· April 2023

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A ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Mantle Cell Lymphoma (MCL) Cells.
Amineh Ghaderi, Wen Zhong, Mohammad Ali Okhovat, Johanna Aschan, Ann Svensson, Johan Schultz

Pharmaceutics· October 2022

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Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2.
Martin Marek, Elizabeth Ramos-Morales, Gisele F A Picchi-Constante, Theresa Bayer, Carina Norström, Johan Schultz

Cell Rep· December 2021

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Targeting the Receptor Tyrosine Kinase ROR1 by Small Molecules.
Mohammad Hojjat-Farsangi, Ali Moshfegh, Johan Schultz, Martin Norin, Thomas Olin

Handb Exp Pharmacol· November 2021

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A ROR1 small molecule inhibitor (KAN0441571C) induced significant apoptosis of ibrutinib-resistant ROR1 CLL cells.
Amineh Ghaderi, Mohammad-Ali Okhovat, Layung Sekar Sih Wikanthi, Ann Svensson, Marzia Palma, Johan Schultz

EJHaem· August 2021

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Predicting ROR1/BCL2 combination targeted therapy of small cell carcinoma of the lung.
Walter Z Wang, Konstantin Shilo, Joseph M Amann, Alyssa Shulman, Mohammad Hojjat-Farsangi, Johan Schultz

Cell Death Dis· June 2021

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ROR1 Is Expressed in Diffuse Large B-Cell Lymphoma (DLBCL) and a Small Molecule Inhibitor of ROR1 (KAN0441571C) Induced Apoptosis of Lymphoma Cells.
Amineh Ghaderi, Amir Hossein Daneshmanesh, Ali Moshfegh, Parviz Kokhaei, Jan Vågberg, Johan Schultz

Biomedicines· June 2020

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Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer.
Rosaria Benedetti, Carmela Dell'Aversana, Tommaso De Marchi, Dante Rotili, Ning Qing Liu, Johan Schultz

Cancers (Basel)· December 2019

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Identification of novel quinazoline derivatives as potent antiplasmodial agents.
Anne Bouchut, Dante Rotili, Christine Pierrot, Sergio Valente, Sophia Lafitte, Johan Schultz

Eur J Med Chem· January 2019

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A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib.
Amir Hossein Daneshmanesh, Mohammad Hojjat-Farsangi, Amineh Ghaderi, Ali Moshfegh, Lotta Hansson, Johan Schultz

PLoS One· December 2018

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Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination.
Nina M S Gustafsson, Katarina Färnegårdh, Nadilly Bonagas, Anna Huguet Ninou, Petra Groth, Johan Schultz

Nat Commun· September 2018

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Schistosome sirtuins as drug targets.
Julien Lancelot, Alejandro Cabezas-Cruz, Stéphanie Caby, Martin Marek, Johan Schultz

Future Med Chem· February 2016

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Fluorescence-based screening assays for the NAD⁺-dependent histone deacetylase smSirt2 from Schistosoma mansoni.
Matthias Schiedel, Martin Marek, Julien Lancelot, Berin Karaman, Ingrid Almlöf, Johan Schultz

J Biomol Screen· January 2015

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A homogeneous HTRF assay for the identification of inhibitors of the TWEAK-Fn14 protein interaction.
Tiziana Benicchi, Sara Iozzi, Andreas Svahn, Hanna Axelsson, Elisa Mori, Johan Schultz

J Biomol Screen· August 2012

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Identification of Plasmodium falciparum spermidine synthase active site binders through structure-based virtual screening.
Micael Jacobsson, Magnus Gäredal, Johan Schultz, Anders Karlén

J Med Chem· May 2008

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Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B).
Agneta Tjernberg, Dan Hallén, Johan Schultz, Stephen James, Kurt Benkestock

Bioorg Med Chem Lett· February 2004

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Site-selective labeling strategies for screening by NMR.
Johan Weigelt, Mats Wikström, Johan Schultz, Maria J P van Dongen

Comb Chem High Throughput Screen· December 2002

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Structure-based screening as applied to human FABP4: a highly efficient alternative to HTS for hit generation.
Maria J P van Dongen, Jonas Uppenberg, Stefan Svensson, Thomas Lundbäck, Tomas Akerud, Johan Schultz

J Am Chem Soc· October 2002

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Structure-based screening and design in drug discovery.
Maria van Dongen, Johan Weigelt, Jonas Uppenberg, Johan Schultz, Mats Wikström

Drug Discov Today· April 2002

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Site-selective screening by NMR spectroscopy with labeled amino acid pairs.
Johan Weigelt, Maria van Dongen, Jonas Uppenberg, Johan Schultz, Mats Wikström

J Am Chem Soc· March 2002

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