Publications by authors named "Jonas Uppenberg"

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Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
Panagis Filippakopoulos, Andrew Low, Timothy D Sharpe, Jonas Uppenberg, Shenggen Yao

J Mol Biol· August 2010

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N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors.
Tjeerd Barf, Fredrik Lehmann, Kristin Hammer, Saba Haile, Eva Axen, Jonas Uppenberg

Bioorg Med Chem Lett· March 2009

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Structure of human argininosuccinate synthetase.
Tobias Karlberg, Ruairi Collins, Susanne van den Berg, Alex Flores, Martin Hammarström, Jonas Uppenberg

Acta Crystallogr D Biol Crystallogr· March 2008

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A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects.
Tove Ostberg, Stefan Svensson, Göran Selén, Jonas Uppenberg, Markus Thor

J Biol Chem· September 2004

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Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target.
Fredik Lehmann, Saba Haile, Eva Axen, Carmen Medina, Jonas Uppenberg

Bioorg Med Chem Lett· September 2004

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Substituted benzylamino-6-(trifluoromethyl)pyrimidin-4(1H)-ones: a novel class of selective human A-FABP inhibitors.
Rune Ringom, Eva Axen, Jonas Uppenberg, Thomas Lundbäck, Lena Rondahl

Bioorg Med Chem Lett· September 2004

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Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators.
Markus Thor, Katarina Beierlein, Graeme Dykes, Anna Lena Gustavsson, Jessica Heidrich, Jonas Uppenberg

Bioorg Med Chem Lett· December 2002

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Identification of residues in the PXR ligand binding domain critical for species specific and constitutive activation.
Tove Ostberg, Göran Bertilsson, Lena Jendeberg, Anders Berkenstam, Jonas Uppenberg

Eur J Biochem· October 2002

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Structure-based screening as applied to human FABP4: a highly efficient alternative to HTS for hit generation.
Maria J P van Dongen, Jonas Uppenberg, Stefan Svensson, Thomas Lundbäck, Tomas Akerud

J Am Chem Soc· October 2002

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Structure-based screening and design in drug discovery.
Maria van Dongen, Johan Weigelt, Jonas Uppenberg, Johan Schultz, Mats Wikström

Drug Discov Today· April 2002

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Site-selective screening by NMR spectroscopy with labeled amino acid pairs.
Johan Weigelt, Maria van Dongen, Jonas Uppenberg, Johan Schultz, Mats Wikström

J Am Chem Soc· March 2002

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