Publications by authors named "John D Elsworth"

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Proteomic Signatures of Epigenetic Age in African Green Monkey Cerebrospinal Fluid and Plasma.
John D Elsworth, Albert Neutzner, Julien Roux, Juozas Gordevicius, Milda Milciute

Aging Cell· October 2025

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African Green Monkeys Respond to Synthetic Aβ Oligomers with Persistent Alzheimer's-like Activation.
Bianca R P Brown, Xiaoting Li, Monica R Grasty, Isabel R Lopez, Sara Dzigurski, John D Elsworth

bioRxiv· October 2025

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Factors That Determine Successful Social Housing of African Green Monkeys () in Same-Sex Pairs and Trios.
Amanda M Murti, Clive C Wilson, Antonio F Pemberton, Tatiana M Corey, Loveness N Dzikiti, John D Elsworth

Vet Sci· December 2024

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Age-associated sex difference in the expression of mitochondria-based redox sensitive proteins and effect of pioglitazone in nonhuman primate brain.
Sumit Jamwal, Jennifer K Blackburn, John D Elsworth

Biol Sex Differ· September 2023

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Intrathecal amyloid-beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's disease.
Dustin R Wakeman, Michael R Weed, Sylvia E Perez, Erika N Cline, Kirsten L Viola, John D Elsworth

Neuropathol Appl Neurobiol· June 2022

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Pioglitazone transiently stimulates paraoxonase-2 expression in male nonhuman primate brain: Implications for sex-specific therapeutics in neurodegenerative disorders.
Jennifer K Blackburn, Sumit Jamwal, Weiwei Wang, John D Elsworth

Neurochem Int· January 2022

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Expression of PON2 isoforms varies among brain regions in male and female African green monkeys.
Sumit Jamwal, Jennifer K Blackburn, John D Elsworth

Free Radic Biol Med· January 2022

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Sex-based disparity in paraoxonase-2 expression in the brains of African green monkeys.
Sumit Jamwal, Jennifer K Blackburn, John D Elsworth

Free Radic Biol Med· May 2021

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PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders.
Sumit Jamwal, Jennifer K Blackburn, John D Elsworth

Pharmacol Ther· March 2021

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Gene therapy and immunotherapy as promising strategies to combat Huntington's disease-associated neurodegeneration: emphasis on recent updates and future perspectives.
Sumit Jamwal, John D Elsworth, Vikrant Rahi, Puneet Kumar

Expert Rev Neurother· November 2020

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Generation of Pluripotent Stem Cells Using Somatic Cell Nuclear Transfer and Induced Pluripotent Somatic Cells from African Green Monkeys.
Young Gie Chung, Montrell Seay, John D Elsworth, D Eugene Redmond

Stem Cells Dev· October 2020

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Pioglitazone activates paraoxonase-2 in the brain: A novel neuroprotective mechanism.
Jennifer K Blackburn, Daniel W Curry, Anna N Thomsen, Robert H Roth, John D Elsworth

Exp Neurol· May 2020

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Parkinson's disease treatment: past, present, and future.
John D Elsworth

J Neural Transm (Vienna)· May 2020

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Human-Monkey Chimeras for Modeling Human Disease: Opportunities and Challenges.
Alejandro De Los Angeles, Insoo Hyun, Stephen R Latham, John D Elsworth, D Eugene Redmond

Methods Mol Biol· March 2020

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Targeting AMPK Signaling as a Neuroprotective Strategy in Parkinson's Disease.
Daniel W Curry, Bernardo Stutz, Zane B Andrews, John D Elsworth

J Parkinsons Dis· October 2019

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Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity.
Bernardo Stutz, Carole Nasrallah, Mariana Nigro, Daniel Curry, Zhong-Wu Liu, John D Elsworth

Mol Metab· June 2019

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ERK-independent African Green monkey pluripotent stem cells in a putative chimera-competent state.
Alejandro De Los Angeles, John D Elsworth, D Eugene Redmond

Biochem Biophys Res Commun· February 2019

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Human-Monkey Chimeras for Modeling Human Disease: Opportunities and Challenges.
Alejandro De Los Angeles, Insoo Hyun, Stephen R Latham, John D Elsworth, D Eugene Redmond

Stem Cells Dev· December 2018

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Molecular and cellular reorganization of neural circuits in the human lineage.
André M M Sousa, Ying Zhu, Mary Ann Raghanti, Robert R Kitchen, Marco Onorati, John D Elsworth

Science· November 2017

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Cognitive performance of juvenile monkeys after chronic fluoxetine treatment.
Mari S Golub, Edward P Hackett, Casey E Hogrefe, Csaba Leranth, John D Elsworth

Dev Cogn Neurosci· August 2017

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Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons.
Jacqueline A Bayliss, Moyra B Lemus, Vanessa V Santos, Minh Deo, Jeffrey S Davies, John D Elsworth

PLoS One· July 2017

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Neural Stem Cells Derived from Human Parthenogenetic Stem Cells Engraft and Promote Recovery in a Nonhuman Primate Model of Parkinson's Disease.
Rodolfo Gonzalez, Ibon Garitaonandia, Maxim Poustovoitov, Tatiana Abramihina, Caleb McEntire, John D Elsworth

Cell Transplant· November 2016

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Acylated but not des-acyl ghrelin is neuroprotective in an MPTP mouse model of Parkinson's disease.
Jacqueline A Bayliss, Moyra Lemus, Vanessa V Santos, Minh Deo, John D Elsworth

J Neurochem· May 2016

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Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease.
Jacqueline A Bayliss, Moyra B Lemus, Romana Stark, Vanessa V Santos, Aiysha Thompson, John D Elsworth

J Neurosci· March 2016

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Proof of concept studies exploring the safety and functional activity of human parthenogenetic-derived neural stem cells for the treatment of Parkinson's disease.
Rodolfo Gonzalez, Ibon Garitaonandia, Andrew Crain, Maxim Poustovoitov, Tatiana Abramihina, John D Elsworth

Cell Transplant· December 2015

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