Publications by authors named "Michael R Weed"

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African Green Monkeys Respond to Synthetic Aβ Oligomers with Persistent Alzheimer's-like Activation.
Bianca R P Brown, Xiaoting Li, Monica R Grasty, Isabel R Lopez, Sara Dzigurski, Michael R Weed

bioRxiv· October 2025

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Intrathecal amyloid-beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's disease.
Dustin R Wakeman, Michael R Weed, Sylvia E Perez, Erika N Cline, Kirsten L Viola

Neuropathol Appl Neurobiol· June 2022

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Dosing, collection, and quality control issues in cerebrospinal fluid research using animal models.
Donna M Barten, Gregory W Cadelina, Michael R Weed

Handb Clin Neurol· June 2018

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Nicotinic alpha 7 receptor agonists EVP-6124 and BMS-933043, attenuate scopolamine-induced deficits in visuo-spatial paired associates learning.
Michael R Weed, Joseph Polino, Laura Signor, Mark Bookbinder, Deborah Keavy

PLoS One· January 2018

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Preclinical Characterization of ()-3-((3,4)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate -Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder.
Linda J Bristow, Jyoti Gulia, Michael R Weed, Bettadapura N Srikumar, Yu-Wen Li

J Pharmacol Exp Ther· December 2017

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B-973, a novel piperazine positive allosteric modulator of the α7 nicotinic acetylcholine receptor.
Debra J Post-Munson, Rick L Pieschl, Thaddeus F Molski, John D Graef, Adam W Hendricson, Michael R Weed

Eur J Pharmacol· March 2017

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The qEEG Signature of Selective NMDA NR2B Negative Allosteric Modulators; A Potential Translational Biomarker for Drug Development.
Deborah Keavy, Linda J Bristow, Digavalli V Sivarao, Margaret Batchelder, Dalton King, Michael R Weed

PLoS One· August 2016

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Negative Allosteric Modulators Selective for The NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains.
Michael R Weed, Mark Bookbinder, Joseph Polino, Deborah Keavy, Rudolf N Cardinal

Neuropsychopharmacology· January 2016

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Effects of X-ray radiation on complex visual discrimination learning and social recognition memory in rats.
Catherine M Davis, Peter G Roma, Elwood Armour, Virginia L Gooden, Joseph V Brady, Michael R Weed

PLoS One· November 2015

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Discovery of D1 Dopamine Receptor Positive Allosteric Modulators: Characterization of Pharmacology and Identification of Residues that Regulate Species Selectivity.
Martin A Lewis, Lisa Hunihan, John Watson, Robert G Gentles, Shuanghua Hu, Michael R Weed

J Pharmacol Exp Ther· September 2015

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Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected].
Paul L Soto, Nancy A Ator, Sundari K Rallapalli, Poonam Biawat, Terry Clayton, Michael R Weed

Neuropsychopharmacology· October 2013

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Long-term exposure to oral methylphenidate or dl-amphetamine mixture in peri-adolescent rhesus monkeys: effects on physiology, behavior, and dopamine system development.
Paul L Soto, Kristin M Wilcox, Yun Zhou, Anil Kumar, Nancy A Ator, Michael R Weed

Neuropsychopharmacology· November 2012

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Blood levels and DA transporter occupancy of orally administered methylphenidate in juvenile rhesus monkeys measured by high resolution PET.
Kristin M Wilcox, Yun Zhou, Dean F Wong, Mohab Alexander, Arman Rahmim, Michael R Weed

Synapse· December 2008

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A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis.
Dongmei Han, F Holger Försterling, Xiaoyan Li, Jeffrey R Deschamps, Damon Parrish, Michael R Weed

Bioorg Med Chem· October 2008

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Neurobehavioral effects of head-only gamma-radiation exposure in rats.
Robert D Hienz, Joseph V Brady, Virginia L Gooden, Marcelo E Vazquez, Michael R Weed

Radiat Res· September 2008

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Consistent, high-level ethanol consumption in pig-tailed macaques via a multiple-session, limited-intake, oral self-dosing procedure.
Michael R Weed, Kristin M Wilcox, Nancy A Ator, Robert D Hienz

Alcohol Clin Exp Res· June 2008

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Impaired performance on the object retrieval-detour test of executive function in the SIV/macaque model of AIDS.
Rachel A Gray, Kristin M Wilcox, M Christine Zink, Michael R Weed

AIDS Res Hum Retroviruses· October 2006

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Morphine withdrawal dramatically reduces lymphocytes in morphine-dependent macaques.
Michael R Weed, Lucy M Carruth, Robert J Adams, Nancy A Ator, Robert D Hienz

J Neuroimmune Pharmacol· September 2006

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Effects of morphine on circadian rhythms of motor activity and body temperature in pig-tailed macaques.
Michael R Weed, Robert D Hienz

Pharmacol Biochem Behav· July 2006

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Neuropsychopathology in the SIV/macaque model of AIDS.
Michael R Weed, David J Steward

Front Biosci· January 2005

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Modeling a task that is sensitive to dementia of the Alzheimer's type: individual differences in acquisition of a visuo-spatial paired-associate learning task in rhesus monkeys.
Michael A Taffe, Michael R Weed, Tannia Gutierrez, Sophia A Davis, Lisa H Gold

Behav Brain Res· March 2004

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Impaired performance on a rhesus monkey neuropsychological testing battery following simian immunodeficiency virus infection.
Michael R Weed, Lisa H Gold, Ilham Polis, George F Koob, Howard S Fox

AIDS Res Hum Retroviruses· January 2004

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Central nervous system correlates of behavioral deficits following simian immunodeficiency virus infection.
Michael R Weed, Robert D Hienz, Joseph V Brady, Robert J Adams, Joseph L Mankowski

J Neurovirol· August 2003

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Cocaine's effects on detection, discrimination, and identification of auditory stimuli by baboons.
Robert D Hienz, Michael R Weed, Troy J Zarcone, Joseph V Brady

Pharmacol Biochem Behav· January 2003

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Cocaine's effects on the discrimination of simple and complex auditory stimuli by baboons.
Robert D Hienz, Michael R Weed, Troy J Zarcone, Joseph V Brady

Pharmacol Biochem Behav· July 2002

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