Publications by authors named "John D Wade"

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Structure and activation of the Drosophila insulin receptor by three Drosophila insulin-like peptides.
Kai Cai, Michelle Ng, Rochele R Yamamoto, Mohammed Akhter Hossain, Catherine Hall, John D Wade

Nat Commun· October 2025

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Developing a Gram-Negative Selective Peptide-Drug Conjugate.
Thomas N G Handley, Alexandra Brakel, Anthony Maxwell, Jie Ding, Sara Hadjigol, John D Wade

ACS Omega· August 2025

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SMYD5 is a ribosomal methyltransferase that trimethylates RPL40 lysine 22 through recognition of a KXY motif.
Joshua J Hamey, Manan Shah, John D Wade, Tara K Bartolec, Richard E H Wettenhall

Cell Rep· April 2025

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Aggregation-prone antimicrobial peptides target gram-negative bacterial nucleic acids and protein synthesis.
Pengyu Chen, Tianmeng Zhang, Chunyuan Li, Praveen Praveen, Kathy Parisi, John D Wade

Acta Biomater· January 2025

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Engineering of a Biologically Active Glycosylated Glucagon-Like Peptide-1 Analogue.
Chaitra Chandrashekar, Feng Lin, Yuji Nishiuchi, Sam F Mohammed, Barbara F White, John D Wade

J Med Chem· May 2024

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Big peptide drugs in a small molecule world.
Laszlo Otvos, John D Wade

Front Chem· December 2023

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Glycosylation Improves the Proteolytic Stability of Exenatide.
Chaitra Chandrashekar, Yuji Nishiuchi, Barbara Fam White, Yanni Arsenakis, Feng Lin, John D Wade

Bioconjug Chem· June 2023

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Editorial: Innovators in chemical biology.
John D Wade, Olivier Renaudet, Matthew A Coleman

Front Chem· November 2022

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Editorial: Editors' showcase: Chemical biology.
John D Wade

Front Chem· August 2022

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Evaluation of Potential DnaK Modulating Proline-Rich Antimicrobial Peptides Identified by Computational Screening.
Thomas N G Handley, Wenyi Li, Nicholas G Welch, Neil M O'Brien-Simpson, Mohammed Akhter Hossain, John D Wade

Front Chem· April 2022

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Systematic comparison of activity and mechanism of antimicrobial peptides against nosocomial pathogens.
Bruce Lin, Andrew Hung, Rong Li, Anders Barlow, William Singleton, John D Wade

Eur J Med Chem· March 2022

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The life and work of Robert (Bob) C. Sheppard.
John D Wade, John H Jones

J Pept Sci· February 2022

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Enhancing proline-rich antimicrobial peptide action by homodimerization: influence of bifunctional linker.
Wenyi Li, Feng Lin, Andrew Hung, Anders Barlow, Marc-Antoine Sani, John D Wade

Chem Sci· February 2022

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Engineering of a Biologically Active Insulin Dimer.
Mengjie Liu, Barbara F White, Praveen Praveen, Wenyi Li, Feng Lin, John D Wade

J Med Chem· December 2021

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Cationic Antimicrobial Peptides Are Leading the Way to Combat Oropathogenic Infections.
Bruce Lin, Rong Li, Thomas N G Handley, John D Wade, Wenyi Li

ACS Infect Dis· November 2021

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Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Michela L Mitchell, Mohammed Akhter Hossain, Feng Lin, Ernesto L Pinheiro-Junior, Steve Peigneur, John D Wade

Biomolecules· November 2021

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Chemical Synthesis and Characterization of a Nonfibrillating Glycoglucagon.
Mengjie Liu, Peishen Zhao, Md Hemayet Uddin, Wenyi Li, Feng Lin, John D Wade

Bioconjug Chem· October 2021

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The Chemical Synthesis of Insulin: An Enduring Challenge.
John A Karas, John D Wade, Mohammed Akhter Hossain

Chem Rev· April 2021

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Chemically modified and conjugated antimicrobial peptides against superbugs.
Wenyi Li, Frances Separovic, Neil M O'Brien-Simpson, John D Wade

Chem Soc Rev· April 2021

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Leptin antagonism inhibits prostate cancer xenograft growth and progression.
Lisa K Philp, Anja Rockstroh, Martin C Sadowski, Atefeh Taherian Fard, Melanie Lehman, John D Wade

Endocr Relat Cancer· April 2021

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Chemical Glycosylation and Its Application to Glucose Homeostasis-Regulating Peptides.
Chaitra Chandrashekar, Mohammed Akhter Hossain, John D Wade

Front Chem· April 2021

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Human glucose-dependent insulinotropic polypeptide (GIP) is an antimicrobial adjuvant re-sensitising multidrug-resistant Gram-negative bacteria.
Da'san M M Jaradat, Nehaya Al-Karablieh, Basmah H M Zaarer, Wenyi Li, Khalil K Y Saleh, John D Wade

Biol Chem· March 2021

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Design of Flavonoid-Based Mimetics of Cationic Antimicrobial Peptides: Discovery, Development, and Applications.
Shuimu Lin, John D Wade, Shouping Liu

Acc Chem Res· January 2021

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(Re)Defining the Proline-Rich Antimicrobial Peptide Family and the Identification of Putative New Members.
Nicholas G Welch, Wenyi Li, Mohammed Akhter Hossain, Frances Separovic, Neil M O'Brien-Simpson, John D Wade

Front Chem· December 2020

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Effects of C-Terminal B-Chain Modifications in a Relaxin 3 Agonist Analogue.
Praveen Praveen, Julien Tailhades, K Johan Rosengren, Mengjie Liu, John D Wade

ACS Med Chem Lett· November 2020

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