Publications by authors named "Shuimu Lin"

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Rational design of ivacaftor-derived antimicrobial peptidomimetics: Membrane-targeting strategy enhances broad-spectrum antimicrobial efficacy against MDR pathogens.
Rongcui Zhong, Lingqing Xu, Jiaxuan Wu, Mengyi He, Suhua Wu, Shuimu Lin

Eur J Med Chem· January 2026

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Boronic acid derivatives inhibit Candida albicans growth by compromising energy metabolism.
Suhua Wu, Venkatesh Mayandi, Eunice Tze Leng Goh, Wenyi Wang, Nuotong Han, Shuimu Lin

J Adv Res· July 2025

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Chondroitin sulfate nanoparticles based on co-delivery dual drug induced ferroptosis in lung cancer cells by disrupting mitochondrial oxidative homeostasis.
He Wang, Shuimu Lin, Jiacui Xie, Xuming Chen, Yating Deng, Linghao Qin

Mater Today Bio· April 2025

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Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis.
Haizhou Li, Wen-Tyng Kang, Yujiahui Zheng, Yonglv He, Rongcui Zhong, Shuimu Lin

Sci Adv· March 2025

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Modular Synthesis of Bioactive Selenoheterocycles for Efficient Cancer Therapy via Electrochemical Selenylation/Cyclization.
Wenyan Xu, Chengwei Zheng, Mu Chen, Xin Deng, Lingmin Zhang, Shuimu Lin

J Med Chem· March 2025

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Development and antimicrobial activity of composite edible films of chitosan and nisin incorporated with perilla essential oil-glycerol monolaurate emulsions.
Zhantong Fang, Yating Yang, Shuimu Lin, Lirong Xu, Shuyi Chen, Chunhong Lin

Food Chem· January 2025

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Development of novel bisphenol derivatives with a membrane-targeting mechanism as potent gram-positive antibacterial agents.
Rongcui Zhong, Zikai Xu, Shujun Zhang, Minghui Zeng, Haizhou Li, Shuimu Lin

Eur J Med Chem· August 2024

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Development of cannabidiol derivatives as potent broad-spectrum antibacterial agents with membrane-disruptive mechanism.
Shanfang Fang, Wen-Tyng Kang, Haizhou Li, Qiongna Cai, Wanxin Liang, Shuimu Lin

Eur J Med Chem· February 2024

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Design of phenothiazine-based cationic amphiphilic derivatives incorporating arginine residues: Potential membrane-active broad-spectrum antimicrobials combating pathogenic bacteria in vitro and in vivo.
Qian Yu, Qiongna Cai, Wanxin Liang, Kewen Zhong, Jiayong Liu, Shuimu Lin

Eur J Med Chem· November 2023

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Electrochemical Selenylation of Sulfoxonium Ylides for the Synthesis of -Diselenides as Antimicrobials against Fungi.
Zhongnan Xu, Jiwen Yao, Kaihui Zhong, Shuimu Lin, Xinwei Hu

J Org Chem· May 2023

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Design, synthesis, and biological evaluation of tetrahydroquinoline amphiphiles as membrane-targeting antimicrobials against pathogenic bacteria and fungi.
Jiayong Liu, Hongxia Li, Qile He, Kaiting Chen, Yongzhi Chen, Shuimu Lin

Eur J Med Chem· December 2022

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Membrane-Active Nonivamide Derivatives as Effective Broad-Spectrum Antimicrobials: Rational Design, Synthesis, and Biological Evaluation.
Qiongna Cai, Qian Yu, Wanxin Liang, Haizhou Li, Jiayong Liu, Shuimu Lin

J Med Chem· December 2022

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Design and Synthesis of Phenyl Sulfide-Based Cationic Amphiphiles as Membrane-Targeting Antimicrobial Agents against Gram-Positive Pathogens.
Wanxin Liang, Qian Yu, Zixian Zheng, Jiayong Liu, Qiongna Cai, Shuimu Lin

J Med Chem· October 2022

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Membrane-Active Antibacterial Agents Based on Calix[4]arene Derivatives: Synthesis and Biological Evaluation.
Shanfang Fang, Yuan-Ye Dang, Haizhou Li, Hongxia Li, Jiayong Liu, Shuimu Lin

Front Chem· February 2022

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Synthesis and biological evaluation of indole-based peptidomimetics as antibacterial agents against Gram-positive bacteria.
Yongzhi Chen, Hongxia Li, Jiayong Liu, Rongcui Zhong, Haizhou Li, Shuimu Lin

Eur J Med Chem· December 2021

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Curcumin prevents As-induced carcinogenesis through regulation of GSK3β/Nrf2.
Yuan-Ye Dang, Hua Luo, Yong-Mei Li, Yang Zhou, Xiu Luo, Shui-Mu Lin

Chin Med· November 2021

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Development of Amphiphilic Coumarin Derivatives as Membrane-Active Antimicrobial Agents with Potent Efficacy against Gram-Positive Pathogenic Bacteria.
Rongcui Zhong, Haizhou Li, Hongxia Li, Shanfang Fang, Jiayong Liu, Shuimu Lin

ACS Infect Dis· October 2021

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Rational Design of Dipicolylamine-Containing Carbazole Amphiphiles Combined with Zn as Potent Broad-Spectrum Antibacterial Agents with a Membrane-Disruptive Mechanism.
Jiayong Liu, Hongxia Li, Haizhou Li, Shanfang Fang, Jinguo Shi, Shuimu Lin

J Med Chem· July 2021

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Design, Synthesis, and Biological Evaluation of Membrane-Active Bakuchiol Derivatives as Effective Broad-Spectrum Antibacterial Agents.
Hongxia Li, Jiayong Liu, Chuan-Fa Liu, Haizhou Li, Jiachun Luo, Shuimu Lin

J Med Chem· May 2021

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Design of Flavonoid-Based Mimetics of Cationic Antimicrobial Peptides: Discovery, Development, and Applications.
Shuimu Lin, John D Wade, Shouping Liu

Acc Chem Res· January 2021

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Potent in vitro and in vivo antimicrobial activity of semisynthetic amphiphilic γ-mangostin derivative LS02 against Gram-positive bacteria with destructive effect on bacterial membrane.
Shuimu Lin, Chunjie Zhu, Hongxia Li, Yongzhi Chen, Shouping Liu

Biochim Biophys Acta Biomembr· September 2020

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Design, synthesis, and evaluation of amphiphilic sofalcone derivatives as potent Gram-positive antibacterial agents.
Shuimu Lin, Yongzhi Chen, Hongxia Li, Jiayong Liu, Shouping Liu

Eur J Med Chem· September 2020

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Development of Highly Potent Carbazole Amphiphiles as Membrane-Targeting Antimicrobials for Treating Gram-Positive Bacterial Infections.
Shuimu Lin, Jiayong Liu, Hongxia Li, Ying Liu, Yongzhi Chen

J Med Chem· September 2020

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In Vitro and in Vivo Evaluation of Membrane-Active Flavone Amphiphiles: Semisynthetic Kaempferol-Derived Antimicrobials against Drug-Resistant Gram-Positive Bacteria.
Shuimu Lin, Hongxia Li, Yiwen Tao, Jiayong Liu, Wenchang Yuan

J Med Chem· June 2020

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Design and synthesis of oligo-lipidated arginyl peptide (OLAP) dimers with enhanced physicochemical activity, peptide stability and their antimicrobial actions against MRSA infections.
Jun-Jie Koh, Shuimu Lin, Wendy Wan Ling Sin, Zhi Hao Ng, Do Yun Jung

Amino Acids· October 2018

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