Publications by authors named "John D York"

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Inositol phosphates dynamically enhance stability, solubility, and catalytic activity of mTOR.
Lucia E Rameh, John D York, Raymond D Blind

J Biol Chem· February 2025

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Multiple inositol phosphate species enhance stability of active mTOR.
Lucia E Rameh, John D York, Raymond D Blind

bioRxiv· May 2024

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Coordinated inositide lipid-phosphatase activities of synaptojanin modulates actin cytoskeleton organization.
Tong Zhang, Andrew T Hale, Shuling Guo, John D York

Adv Biol Regul· January 2024

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Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization.
Kevin R Bersell, Tao Yang, Jonathan D Mosley, Andrew M Glazer, Andrew T Hale, John D York

Circulation· March 2023

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Inhibition of p53 Sulfoconjugation Prevents Oxidative Hepatotoxicity and Acute Liver Failure.
Pengfei Xu, Yue Xi, Pengcheng Wang, Zigmund Luka, Meishu Xu, John D York

Gastroenterology· April 2022

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Bisphosphate nucleotidase 2 (BPNT2), a molecular target of lithium, regulates chondroitin sulfation patterns in the cerebral cortex and hippocampus.
Brynna S Eisele, Alice J Wu, Zigmund Luka, Andrew T Hale, John D York

Adv Biol Regul· January 2022

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Sulfation of glycosaminoglycans depends on the catalytic activity of lithium-inhibited phosphatase BPNT2 in vitro.
Brynna S Eisele, Zigmund Luka, Alice J Wu, Fei Yang, Andrew T Hale, John D York

J Biol Chem· November 2021

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A structural basis for lithium and substrate binding of an inositide phosphatase.
D Eric Dollins, Jian-Ping Xiong, Stuart Endo-Streeter, David E Anderson, Vinay S Bansal, John D York

J Biol Chem· September 2021

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Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis.
Pengfei Xu, Yue Xi, Junjie Zhu, Min Zhang, Zigmund Luka, John D York

Gastroenterology· July 2021

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Metabolic Labeling of Inositol Phosphates and Phosphatidylinositols in Yeast and Mammalian Cells.
Andrew T Hale, Bradley P Clarke, John D York

Methods Mol Biol· January 2021

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Modulation of sulfur assimilation metabolic toxicity overcomes anemia and hemochromatosis in mice.
Andrew T Hale, Rachel E Brown, Zigmund Luka, Benjamin H Hudson, Pranathi Matta, John D York

Adv Biol Regul· May 2020

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Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling.
D Eric Dollins, Wenli Bai, Peter C Fridy, James C Otto, Julie L Neubauer, John D York

Proc Natl Acad Sci U S A· April 2020

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A synthetic biological approach to reconstitution of inositide signaling pathways in bacteria.
Bradley P Clarke, Brandon L Logeman, Andrew T Hale, Zigmund Luka, John D York

Adv Biol Regul· August 2019

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Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
Dan E McNamara, Cole M Dovey, Andrew T Hale, Giovanni Quarato, Christy R Grace, John D York

Cell Chem Biol· June 2019

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MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.
Cole M Dovey, Jonathan Diep, Bradley P Clarke, Andrew T Hale, Dan E McNamara, John D York

Mol Cell· June 2018

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Modulation of intestinal sulfur assimilation metabolism regulates iron homeostasis.
Benjamin H Hudson, Andrew T Hale, Ryan P Irving, Shenglan Li, John D York

Proc Natl Acad Sci U S A· March 2018

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Inositol phosphate multikinase dependent transcriptional control.
Ace J Hatch, Audrey R Odom, John D York

Adv Biol Regul· May 2017

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Structural analyses of sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis.
Tatiana Y Hargrove, Laura Friggeri, Zdzislaw Wawrzak, Aidong Qi, William J Hoekstra, John D York

J Biol Chem· April 2017

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Balloon-Occluded Retrograde Transvenous Obliteration of a Gastric Vascular Malformation: An Innovative Approach to Treatment of a Rare Condition.
Catherine E Hansing, Joseph P Marquardt, Daniel M Sutton, John D York

Cardiovasc Intervent Radiol· February 2017

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Blast Injuries: From Improvised Explosive Device Blasts to the Boston Marathon Bombing.
Ajay K Singh, Noah G Ditkofsky, John D York, Hani H Abujudeh, Laura A Avery

Radiographics· October 2016

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A tribute to Philip W. Majerus.
John D York, P Roy Vagelos

J Clin Invest· September 2016

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Inositol phosphate kinase 2 is required for imaginal disc development in Drosophila.
Andrew M Seeds, Marco M Tsui, Christine Sunu, Eric P Spana, John D York

Proc Natl Acad Sci U S A· December 2015

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Structural basis of lipid binding for the membrane-embedded tetraacyldisaccharide-1-phosphate 4'-kinase LpxK.
Ryan P Emptage, Nam K Tonthat, John D York, Maria A Schumacher, Pei Zhou

J Biol Chem· August 2014

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Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response.
Niyas Kudukkil Pulloor, Sajith Nair, Kathleen McCaffrey, Aleksandar D Kostic, Pradeep Bist, John D York

PLoS Pathog· February 2014

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Tissue-specific regulation of 3'-nucleotide hydrolysis and nucleolar architecture.
Benjamin H Hudson, John D York

Adv Biol Regul· January 2014

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