Publications by authors named "John G Collard"

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The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network.
Saskia I J Ellenbroek, Sandra Iden, John G Collard

Small GTPases· April 2013

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Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration.
Shujie Wang, Takashi Watanabe, Kenji Matsuzawa, Akira Katsumi, Mai Kakeno, John G Collard

J Cell Biol· October 2012

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Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis.
Sandra Iden, Wilhelmina E van Riel, Ronny Schäfer, Ji-Ying Song, Tomonori Hirose, John G Collard

Cancer Cell· September 2012

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Concepts of metastasis in flux: the stromal progression model.
Jonathan P Sleeman, Gerhard Christofori, Riccardo Fodde, John G Collard, Geert Berx

Semin Cancer Biol· June 2012

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Cell polarity proteins and cancer.
Saskia I J Ellenbroek, Sandra Iden, John G Collard

Semin Cancer Biol· June 2012

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The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.
Audrey Gérard, Rob A van der Kammen, Hans Janssen, Saskia I Ellenbroek, John G Collard

Blood· June 2009

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Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling.
Amra Hajdo-Milasinovic, Rob A van der Kammen, Zvezdana Moneva, John G Collard

J Cell Sci· June 2009

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Crosstalk between small GTPases and polarity proteins in cell polarization.
Sandra Iden, John G Collard

Nat Rev Mol Cell Biol· November 2008

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The Rac activator Tiam1 and Ras-induced oncogenesis.
Kristin Strumane, Tomasz P Rygiel, John G Collard

Methods Enzymol· June 2008

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Rho GTPases: functions and association with cancer.
Saskia I J Ellenbroek, John G Collard

Clin Exp Metastasis· April 2008

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The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation.
Tomasz P Rygiel, Alexander E Mertens, Kristin Strumane, Rob van der Kammen, John G Collard

J Cell Sci· April 2008

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Increased Rac activity is required for the progression of T-lymphomas induced by Pten-deficiency.
Kristin Strumane, Ji-Ying Song, Inge Baas, John G Collard

Leuk Res· January 2008

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The Par-Tiam1 complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity.
D Michiel Pegtel, Saskia I J Ellenbroek, Alexander E E Mertens, Rob A van der Kammen, Johan de Rooij, John G Collard

Curr Biol· October 2007

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The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization.
Audrey Gérard, Alexander E E Mertens, Rob A van der Kammen, John G Collard

J Cell Biol· March 2007

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Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells.
Amra Hajdo-Milasinović, Saskia I J Ellenbroek, Saskia van Es, Babet van der Vaart, John G Collard

J Cell Sci· February 2007

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Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.
Jean Paul Ten Klooster, Eva E Evers, Lennert Janssen, Laura M Machesky, Frits Michiels, John G Collard

Biochem J· July 2006

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Tiam1 takes PARt in cell polarity.
Alexander E E Mertens, D Michiel Pegtel, John G Collard

Trends Cell Biol· June 2006

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The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.
Angeliki Malliri, Tomasz P Rygiel, Rob A van der Kammen, Ji-Ying Song, Rainer Engers, John G Collard

J Biol Chem· January 2006

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The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.
Irene H L Hamelers, Cristina Olivo, Alexander E E Mertens, D Michiel Pegtel, Rob A van der Kammen, John G Collard

J Cell Biol· December 2005

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The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex.
Alexander E E Mertens, Tomasz P Rygiel, Cristina Olivo, Rob van der Kammen, John G Collard

J Cell Biol· September 2005

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The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model.
Meghan E Minard, Matthew H Herynk, John G Collard, Gary E Gallick

Oncogene· April 2005

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Activation of gef-h1, a guanine nucleotide exchange factor for RhoA, by DNA transfection.
Marcus Brecht, Agatha C M Steenvoorden, John G Collard, Susanne Luf, Dorothee Erz

Int J Cancer· February 2005

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The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism.
Katharina Uhlenbrock, Alexander Eberth, Ulrike Herbrand, Neda Daryab, Patricia Stege, John G Collard

J Cell Sci· September 2004

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Rap1 regulates E-cadherin-mediated cell-cell adhesion.
Leo S Price, Amra Hajdo-Milasinovic, Jun Zhao, Fried J T Zwartkruis, John G Collard

J Biol Chem· August 2004

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Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases.
Aukje W Zimmerman, Judith M D T Nelissen, Sjenet E van Emst-de Vries, Peter H G M Willems, Frank de Lange, John G Collard

J Cell Sci· June 2004

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