Publications by authors named "John Groffen"

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Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia.
Khuchtumur Bum-Erdene, Patrick M Collins, Matthew W Hugo, Somayeh S Tarighat, Fei Fei, John Groffen

J Med Chem· April 2022

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Pre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein.
Eun Ji Joo, Brian R Wasik, Colin Parrish, Helicia Paz, Martina Mϋhlenhoff, John Groffen

Sci Rep· November 2018

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Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008.
Helicia Paz, Eun Ji Joo, Chih-Hsing Chou, Fei Fei, Kevin H Mayo, John Groffen

J Exp Clin Cancer Res· March 2018

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B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3.
Fei Fei, Eun Ji Joo, Somayeh S Tarighat, Isabelle Schiffer, Helicia Paz, John Groffen

Oncotarget· May 2015

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Effector-mediated eradication of precursor B acute lymphoblastic leukemia with a novel Fc-engineered monoclonal antibody targeting the BAFF-R.
Reshmi Parameswaran, Min Lim, Fei Fei, Hisham Abdel-Azim, Anna Arutyunyan, John Groffen

Mol Cancer Ther· June 2014

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Abr, a negative regulator of Rac, attenuates cockroach allergen-induced asthma in a mouse model.
Dapeng Gong, Fei Fei, Min Lim, Min Yu, John Groffen

J Immunol· November 2013

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Lack of bcr and abr promotes hypoxia-induced pulmonary hypertension in mice.
Min Yu, Dapeng Gong, Min Lim, Anna Arutyunyan, John Groffen

PLoS One· May 2013

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O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia.
Reshmi Parameswaran, Min Lim, Anna Arutyunyan, Hisham Abdel-Azim, Christian Hurtz, John Groffen

J Exp Med· April 2013

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Expression of cassini, a murine gamma-satellite sequence conserved in evolution, is regulated in normal and malignant hematopoietic cells.
Anna Arutyunyan, Sonia Stoddart, Sun-ju Yi, Fei Fei, Min Lim, Paula Groffen, John Groffen

BMC Genomics· August 2012

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Environment-mediated drug resistance in Bcr/Abl-positive acute lymphoblastic leukemia.
Niklas Feldhahn, Anna Arutyunyan, Sonia Stoddart, Bin Zhang, Sabine Schmidhuber, John Groffen

Oncoimmunology· August 2012

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TGFβ signaling plays a critical role in promoting alternative macrophage activation.
Dapeng Gong, Wei Shi, Sun-ju Yi, Hui Chen, John Groffen

BMC Immunol· June 2012

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Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib).
Fei Fei, Min Lim, Sabine Schmidhuber, Jürgen Moll, John Groffen

Mol Cancer· June 2012

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Bcr is a substrate for Transglutaminase 2 cross-linking activity.
Sun-Ju Yi, John Groffen, Nora Heisterkamp

BMC Biochem· February 2011

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The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac.
Fei Fei, Soo-Mi Kweon, Leena Haataja, Paulo De Sepulveda, John Groffen

BMC Biochem· December 2010

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Diet-induced obesity accelerates acute lymphoblastic leukemia progression in two murine models.
Jason P Yun, James W Behan, Nora Heisterkamp, Anna Butturini, Lars Klemm, John Groffen

Cancer Prev Res (Phila)· October 2010

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Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.
Daeyoung Oh, Seungnam Han, Jinsoo Seo, Jae-Ran Lee, Jeonghoon Choi, John Groffen

J Neurosci· October 2010

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Cell type-specific expression of adenomatous polyposis coli in lung development, injury, and repair.
Aimin Li, Yiming Xing, Belinda Chan, Nora Heisterkamp, John Groffen

Dev Dyn· August 2010

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A functional receptor for B-cell-activating factor is expressed on human acute lymphoblastic leukemias.
Reshmi Parameswaran, Markus Müschen, Yong-Mi Kim, John Groffen, Nora Heisterkamp

Cancer Res· June 2010

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Activity of the Aurora kinase inhibitor VX-680 against Bcr/Abl-positive acute lymphoblastic leukemias.
Fei Fei, Sonia Stoddart, John Groffen, Nora Heisterkamp

Mol Cancer Ther· May 2010

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Transglutaminase 2 regulates the GTPase-activating activity of Bcr.
Sun-Ju Yi, John Groffen, Nora Heisterkamp

J Biol Chem· December 2009

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Bcr and Abr cooperate in negatively regulating acute inflammatory responses.
Jess M Cunnick, Sabine Schmidhuber, Gang Chen, Min Yu, Sun-Ju Yi, John Groffen

Mol Cell Biol· November 2009

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The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.
Lars Klemm, Cihangir Duy, Ilaria Iacobucci, Stefan Kuchen, Gregor von Levetzow, John Groffen

Cancer Cell· September 2009

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Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.
Daniel Trageser, Ilaria Iacobucci, Rahul Nahar, Cihangir Duy, Gregor von Levetzow, John Groffen

J Exp Med· August 2009

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Bcr/Abl P190 interaction with Spa-1, a GTPase activating protein for the small GTPase Rap1.
Sun-Ju Yi, Hyung-Taek Lee, John Groffen, Nora Heisterkamp

Int J Mol Med· October 2008

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The human gamma-glutamyltransferase gene family.
Nora Heisterkamp, John Groffen, David Warburton, Tam P Sneddon

Hum Genet· May 2008

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