Publications by authors named "John Lepore"

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Corrigendum: Ephrin-B2 controls PDGFRβ internalization and signaling.
Akiko Nakayama, Masanori Nakayama, Christopher J Turner, Susanne Höing, John J Lepore

Genes Dev· November 2025

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Assessing dental student knowledge on cannabis and demonstrating the need for cannabis education.
Jessica S Kruger, John Lepore, Madelyn Mascaro, Gina Mersereau, Alyssa Tzetzo

J Dent Educ· August 2024

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A Randomized, Placebo-Controlled Trial to Assess the Effects of 8 Weeks of Administration of GSK256073, a Selective GPR109A Agonist, on High-Density Lipoprotein Cholesterol in Subjects With Dyslipidemia.
Eric J Olson, Kelly M Mahar, Thomas F Haws, Michael J Fossler, Feng Gao, John J Lepore

Clin Pharmacol Drug Dev· October 2019

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Daprodustat for anemia: a 24-week, open-label, randomized controlled trial in participants with chronic kidney disease.
Louis Holdstock, Borut Cizman, Amy M Meadowcroft, Nandita Biswas, Brendan M Johnson, John J Lepore

Clin Kidney J· February 2019

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Daprodustat for anemia: a 24-week, open-label, randomized controlled trial in participants on hemodialysis.
Amy M Meadowcroft, Borut Cizman, Louis Holdstock, Nandita Biswas, Brendan M Johnson, John J Lepore

Clin Kidney J· February 2019

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Correction to: HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction induced injury.
Andrew N Billin, Samuel E Honeycutt, Alan V McDougal, Jaclyn P Kerr, Zhe Chen, John Lepore

Skelet Muscle· December 2018

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HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury.
Andrew N Billin, Samuel E Honeycutt, Alan V McDougal, Jaclyn P Kerr, Zhe Chen, John Lepore

Skelet Muscle· November 2018

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Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis Subjects.
Tadao Akizawa, Yoshiharu Tsubakihara, Masaomi Nangaku, Yukihiro Endo, Hiromu Nakajima, John Lepore

Am J Nephrol· January 2018

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The prolyl 4-hydroxylase inhibitor GSK360A decreases post-stroke brain injury and sensory, motor, and cognitive behavioral deficits.
Jin Zhou, Jie Li, Daniel M Rosenbaum, Jian Zhuang, Carrie Poon, John Lepore

PLoS One· October 2017

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The Selection and Control of Starting Materials Should be Governed by Science and Risk-Based Approaches.
Timothy J N Watson, Roger Nosal, John Lepore, Frank Montgomery

AAPS J· January 2017

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Effects of the Novel Long-Acting GLP-1 Agonist, Albiglutide, on Cardiac Function, Cardiac Metabolism, and Exercise Capacity in Patients With Chronic Heart Failure and Reduced Ejection Fraction.
John J Lepore, Eric Olson, Laura Demopoulos, Thomas Haws, Zixing Fang

JACC Heart Fail· July 2016

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Four-Week Studies of Oral Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor GSK1278863 for Treatment of Anemia.
Louis Holdstock, Amy M Meadowcroft, Rayma Maier, Brendan M Johnson, Delyth Jones, John J Lepore

J Am Soc Nephrol· April 2016

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Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction: A Randomized Clinical Trial.
Michelle L O'Donoghue, Ruchira Glaser, Matthew A Cavender, Philip E Aylward, Marc P Bonaca, John J Lepore

JAMA· April 2016

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Cardioprotection Resulting from Glucagon-Like Peptide-1 Administration Involves Shifting Metabolic Substrate Utilization to Increase Energy Efficiency in the Rat Heart.
Karpagam Aravindhan, Weike Bao, Mark R Harpel, Robert N Willette, John J Lepore

PLoS One· March 2016

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Short-term treatment with a novel HIF-prolyl hydroxylase inhibitor (GSK1278863) failed to improve measures of performance in subjects with claudication-limited peripheral artery disease.
Eric Olson, Laura Demopoulos, Thomas F Haws, Erding Hu, Zixing Fang, John Lepore

Vasc Med· December 2014

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Platelet aggregation unchanged by lipoprotein-associated phospholipase A₂ inhibition: results from an in vitro study and two randomized phase I trials.
Bonnie C Shaddinger, Yanmei Xu, James H Roger, Colin H Macphee, Malcolm Handel, John J Lepore

PLoS One· November 2014

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Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial.
L Kristin Newby, Michael S Marber, Chiara Melloni, Lea Sarov-Blat, Laura H Aberle, John J Lepore

Lancet· September 2014

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Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Kinya Seo, Peter P Rainer, Virginia Shalkey Hahn, Dong-Ik Lee, Su-Hyun Jo, John J Lepore

Proc Natl Acad Sci U S A· January 2014

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Ephrin-B2 controls PDGFRβ internalization and signaling.
Akiko Nakayama, Masanori Nakayama, Christopher J Turner, Susanne Höing, John J Lepore

Genes Dev· December 2013

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Novel fusion of GLP-1 with a domain antibody to serum albumin prolongs protection against myocardial ischemia/reperfusion injury in the rat.
Weike Bao, Lucy J Holt, Rob D Prince, Gavin X Jones, Karpagam Aravindhan, John J Lepore

Cardiovasc Diabetol· October 2013

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Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart.
Ronald J Vagnozzi, Gregory J Gatto, Lara S Kallander, Nicholas E Hoffman, Karthik Mallilankaraman, John J Lepore

Sci Transl Med· October 2013

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Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype.
Christine Y Ivashchenko, Gordon C Pipes, Irina M Lozinskaya, Zuojun Lin, Xu Xiaoping, John J Lepore

Am J Physiol Heart Circ Physiol· September 2013

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An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure.
Kevin S Thorneloe, Mui Cheung, Weike Bao, Hasan Alsaid, Stephen Lenhard, John J Lepore

Sci Transl Med· November 2012

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Comparison of soluble guanylate cyclase stimulators and activators in models of cardiovascular disease associated with oxidative stress.
Melissa H Costell, Nicolas Ancellin, Roberta E Bernard, Shufang Zhao, John J Upson, John J Lepore

Front Pharmacol· October 2012

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Effects of p38 mitogen-activated protein kinase inhibition on vascular and systemic inflammation in patients with atherosclerosis.
Maysoon Elkhawad, James H F Rudd, Lea Sarov-Blat, Gengqian Cai, Richard Wells, John J Lepore

JACC Cardiovasc Imaging· September 2012

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