Publications by authors named "John Lydeard"

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Development of a gene edited next-generation hematopoietic cell transplant to enable acute myeloid leukemia treatment by solving off-tumor toxicity.
John R Lydeard, Michelle I Lin, Huanying Gary Ge, Amanda Halfond, Shu Wang

Mol Ther Methods Clin Dev· December 2023

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Erratum: Development of a gene edited next-generation hematopoietic cell transplant to enable acute myeloid leukemia treatment by solving off-tumor toxicity.
John R Lydeard, Michelle I Lin, Huanying Gary Ge, Amanda Halfond, Shu Wang

Mol Ther Methods Clin Dev· December 2023

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MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity.
Lydie Naulé, Alessandra Mancini, Sidney A Pereira, Brandon M Gassaway, John R Lydeard

JCI Insight· April 2023

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Corrigendum: Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.
Malavika Raman, Mikhail Sergeev, Maija Garnaas, John R Lydeard, Edward L Huttlin

Nat Cell Biol· March 2016

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Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.
Malavika Raman, Mikhail Sergeev, Maija Garnaas, John R Lydeard, Edward L Huttlin

Nat Cell Biol· October 2015

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Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.
Eric S Fischer, Kerstin Böhm, John R Lydeard, Haidi Yang, Michael B Stadler

Nature· August 2014

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Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8.
Daniel C Scott, Vladislav O Sviderskiy, Julie K Monda, John R Lydeard, Shein Ei Cho

Cell· June 2014

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Building and remodelling Cullin-RING E3 ubiquitin ligases.
John R Lydeard, Brenda A Schulman, J Wade Harper

EMBO Rep· December 2013

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Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.
Julie K Monda, Daniel C Scott, Darcie J Miller, John Lydeard, David King

Structure· January 2013

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A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.
Brenda C O'Connell, Britt Adamson, John R Lydeard, Mathew E Sowa, Alberto Ciccia

Mol Cell· November 2010

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Inhibitors for E3 ubiquitin ligases.
John R Lydeard, J Wade Harper

Nat Biotechnol· July 2010

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Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.
John R Lydeard, Zachary Lipkin-Moore, Yi-Jun Sheu, Bruce Stillman, Peter M Burgers

Genes Dev· June 2010

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Sgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends.
John R Lydeard, Zachary Lipkin-Moore, Suvi Jain, Vinay V Eapen, James E Haber

PLoS Genet· May 2010

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A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair.
Suvi Jain, Neal Sugawara, John Lydeard, Moreshwar Vaze, Nicolas Tanguy Le Gac

Genes Dev· February 2009

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Break-induced replication and telomerase-independent telomere maintenance require Pol32.
John R Lydeard, Suvi Jain, Miyuki Yamaguchi, James E Haber

Nature· August 2007

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