Publications by authors named "John P Redrobe"

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Mice heterozygous for an inactivated allele of the schizophrenia associated Brd1 gene display selective cognitive deficits with translational relevance to schizophrenia.
Per Qvist, Anto P Rajkumar, John P Redrobe, Mette Nyegaard, Jane H Christensen

Neurobiol Learn Mem· May 2017

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Characterisation of Lu AF33241: A novel, brain-penetrant, dual inhibitor of phosphodiesterase (PDE) 2A and PDE10A.
John P Redrobe, Lars K Rasmussen, Claus T Christoffersen, Christoffer Bundgaard, Morten Jørgensen

Eur J Pharmacol· August 2015

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In vitro and in vivo characterisation of Lu AF64280, a novel, brain penetrant phosphodiesterase (PDE) 2A inhibitor: potential relevance to cognitive deficits in schizophrenia.
John P Redrobe, Morten Jørgensen, Claus T Christoffersen, Liliana P Montezinho, Jesper F Bastlund

Psychopharmacology (Berl)· August 2014

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Discovery and optimization of Lu AF58801, a novel, selective and brain penetrant positive allosteric modulator of alpha-7 nicotinic acetylcholine receptors: attenuation of subchronic phencyclidine (PCP)-induced cognitive deficits in rats following oral administration.
Jørgen Eskildsen, John P Redrobe, Anette G Sams, Kim Dekermendjian, Morten Laursen

Bioorg Med Chem Lett· January 2014

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A combined α7 nicotinic acetylcholine receptor agonist and monoamine reuptake inhibitor, NS9775, represents a novel profile with potential benefits in emotional and cognitive disturbances.
Jesper T Andreasen, John P Redrobe, Elsebet Ø Nielsen, Jeppe K Christensen, Gunnar M Olsen

Neuropharmacology· October 2013

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RO4938581, a GABAAα5 modulator, displays strong CYP1A2 autoinduction properties in rats.
Christoffer Bundgaard, Lassina Badolo, John P Redrobe

Biochem Pharmacol· May 2013

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CyPPA, a Positive SK3/SK2 Modulator, Reduces Activity of Dopaminergic Neurons, Inhibits Dopamine Release, and Counteracts Hyperdopaminergic Behaviors Induced by Methylphenidate.
Kjartan F Herrik, John P Redrobe, Dorte Holst, Charlotte Hougaard, Karin Sandager-Nielsen

Front Pharmacol· October 2012

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Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats.
John P Redrobe, Lisbeth Elster, Kristen Frederiksen, Christoffer Bundgaard, Inge E M de Jong

Psychopharmacology (Berl)· June 2012

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Combined α7 nicotinic acetylcholine receptor agonism and partial serotonin transporter inhibition produce antidepressant-like effects in the mouse forced swim and tail suspension tests: a comparison of SSR180711 and PNU-282987.
Jesper T Andreasen, John P Redrobe, Elsebet Ø Nielsen

Pharmacol Biochem Behav· January 2012

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Translational Aspects of the Novel Object Recognition Task in Rats Abstinent Following Sub-Chronic Treatment with Phencyclidine (PCP): Effects of Modafinil and Relevance to Cognitive Deficits in Schizophrenia.
John P Redrobe, Sascha Bull, Niels Plath

Front Psychiatry· November 2011

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Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim test.
Jesper T Andreasen, Elsebet Ø Nielsen, Jeppe K Christensen, Gunnar M Olsen, Dan Peters, John P Redrobe

J Psychopharmacol· October 2011

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Can small molecules provide truly effective enhancement of cognition? Current achievements and future directions.
Niels Plath, Linda Lerdrup, Peter Hjørringgaard Larsen, John Paul Redrobe

Expert Opin Investig Drugs· June 2011

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Chronic oral nicotine increases brain [3H]epibatidine binding and responsiveness to antidepressant drugs, but not nicotine, in the mouse forced swim test.
Jesper T Andreasen, Elsebet O Nielsen, John P Redrobe

Psychopharmacology (Berl)· August 2009

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alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment.
Morten S Thomsen, Ditte Z Christensen, Henrik H Hansen, John P Redrobe, Jens D Mikkelsen

Neuropharmacology· July 2009

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Antidepressant-like effects of nicotine and mecamylamine in the mouse forced swim and tail suspension tests: role of strain, test and sex.
Jesper T Andreasen, John P Redrobe

Behav Pharmacol· May 2009

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Cognitive deficits in the rat chronic mild stress model for depression: relation to anhedonic-like responses.
Kim Henningsen, Jesper T Andreasen, Elena V Bouzinova, Magdalena N Jayatissa, Morten S Jensen, John P Redrobe

Behav Brain Res· March 2009

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Effects of neuronal Kv7 potassium channel activators on hyperactivity in a rodent model of mania.
John P Redrobe, Alexander N Nielsen

Behav Brain Res· March 2009

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Nicotine, but not mecamylamine, enhances antidepressant-like effects of citalopram and reboxetine in the mouse forced swim and tail suspension tests.
Jesper T Andreasen, John P Redrobe

Behav Brain Res· January 2009

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Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice.
John P Redrobe, Elsebet Ø Nielsen, Jeppe K Christensen, Dan Peters, Daniel B Timmermann

Eur J Pharmacol· January 2009

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Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan.
Jacob P R Jacobsen, Elsebet Ø Nielsen, Rene Hummel, John Paul Redrobe, Naheed Mirza

Psychopharmacology (Berl)· August 2008

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Role of serotonin (5-HT) in the antidepressant-like properties of neuropeptide Y (NPY) in the mouse forced swim test.
John P Redrobe, Yvan Dumont, Alain Fournier, Glen B Baker, Rémi Quirion

Peptides· August 2005

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Characterization of neuropeptide Y, Y(2) receptor knockout mice in two animal models of learning and memory processing.
John Paul Redrobe, Yvan Dumont, Herbert Herzog, Rémi Quirion

J Mol Neurosci· June 2004

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Neuropeptide Y (NPY) Y2 receptors mediate behaviour in two animal models of anxiety: evidence from Y2 receptor knockout mice.
John P Redrobe, Yvan Dumont, Herbert Herzog, Rémi Quirion

Behav Brain Res· May 2003

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Neuropeptide Y (NPY) and depression: from animal studies to the human condition.
John P Redrobe, Yvan Dumont, Rémi Quirion

Life Sci· November 2002

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The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y.
Ants Kask, Jaanus Harro, Stephan von Hörsten, John P Redrobe, Yvan Dumont

Neurosci Biobehav Rev· May 2002

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