Publications by authors named "John Post"

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Mechanistic insights into dual-active liver and blood-stage antiplasmodials.
Mukul Rawat, Nonlawat Boonyalai, Cindy Smidt, Madeline R Luth, Daisy Chen, John Post

mBio· November 2025

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Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening.
De Lin, Lesley-Anne Pearson, Shamshad Ahmad, Sandra O'Neill, John Post

SLAS Discov· September 2025

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Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.
Susan H Davis, Michael Mathieson, Kirsteen I Buchanan, Alice Dawson, Alasdair Smith, John M Post

J Med Chem· August 2025

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Mechanistic Insights into Dual-Active Liver and Blood-Stage Antiplasmodials.
Mukul Rawat, Nonlawat Boonyalai, Cindy Smidt, Madeline R Luth, Daisy Chen, John Post

bioRxiv· August 2025

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lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.
Nicola Caldwell, Caroline Peet, Peter Miller, Beatrice L Colon, Malcolm G Taylor, John Post, Vincent Postis

Sci Transl Med· October 2024

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Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.
Simon R Green, Caroline Wilson, Thomas C Eadsforth, Avinash S Punekar, Fabio K Tamaki, John M Post

J Med Chem· November 2023

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Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.
Simon R Green, Susan H Davis, Sebastian Damerow, Curtis A Engelhart, Michael Mathieson, John Post

Nat Commun· October 2022

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Toolkit of Approaches To Support Target-Focused Drug Discovery for Lysyl tRNA Synthetase.
Rachel Milne, Natalie Wiedemar, Victoriano Corpas-Lopez, Eoin Moynihan, Richard J Wall, John M Post

ACS Infect Dis· September 2022

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Assessing conservation status with extensive but low-resolution data: Application of frequentist and Bayesian models to endangered Athabasca River rainbow trout.
John R Post, Hillary G M Ward, Kyle L Wilson, George L Sterling, Ariane Cantin

Conserv Biol· June 2022

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Neutral and adaptive drivers of genomic change in introduced brook trout () populations revealed by pooled sequencing.
Brent Brookes, Hyung-Bae Jeon, Alison M Derry, John R Post, Sean M Rogers

Ecol Evol· February 2022

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Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Stelios Chrysostomou, Rajat Roy, Filippo Prischi, Lucksamon Thamlikitkul, Kathryn L Chapman, John Post

Sci Transl Med· July 2021

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Targeting CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.
Joanna C Evans, Dinakaran Murugesan, John M Post, Vitor Mendes, Zhe Wang

ACS Infect Dis· June 2021

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Compartmentation of β -adrenoceptor stimulated cAMP responses by phosphodiesterase types 2 and 3 in cardiac ventricular myocytes.
Michael W Rudokas, John P Post, Alejandra Sataray-Rodriguez, Rinzhin T Sherpa, Karni S Moshal

Br J Pharmacol· April 2021

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Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.
Vitor Mendes, Simon R Green, Joanna C Evans, Jeannine Hess, Michal Blaszczyk, John Post

Nat Commun· January 2021

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Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase.
Leah S Torrie, David A Robinson, Michael G Thomas, Judith V Hobrath, Sharon M Shepherd, John M Post

ACS Infect Dis· May 2020

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Life-history variation along environmental and harvest clines of a northern freshwater fish: Plasticity and adaptation.
Kyle L Wilson, Joe De Gisi, Christopher L Cahill, Oliver E Barker, John R Post

J Anim Ecol· May 2019

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Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Beatriz Baragaña, Barbara Forte, Ryan Choi, Stephen Nakazawa Hewitt, Juan A Bueren-Calabuig, John Post

Proc Natl Acad Sci U S A· April 2019

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Identification of UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening.
Ohm Prakash, Jana Führing, John Post, Sharon M Shepherd, Thomas C Eadsforth

Molecules· March 2019

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Opinion: Governing the recreational dimension of global fisheries.
Robert Arlinghaus, Joshua K Abbott, Eli P Fenichel, Stephen R Carpenter, Len M Hunt, John R Post

Proc Natl Acad Sci U S A· March 2019

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Metabolic Scope as a Proximate Constraint on Individual Behavioral Variation: Effects on Personality, Plasticity, and Predictability.
Peter A Biro, Theodore Garland, Christa Beckmann, Beata Ujvari, Frederic Thomas, John R Post

Am Nat· August 2018

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Habitat availability and ontogenetic shifts alter bottlenecks in size-structured fish populations.
Ariane Cantin, John R Post

Ecology· July 2018

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Interaction of ecological and angler processes: experimental stocking in an open access, spatially structured fishery.
Jonathan A Mee, John R Post, Hillary Ward, Kyle L Wilson, Eric Newton

Ecol Appl· September 2016

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Supply-demand equilibria and the size-number trade-off in spatially structured recreational fisheries.
Kyle L Wilson, Ariane Cantin, Hillary G M Ward, Eric R Newton, Jonathan A Mee, John R Post

Ecol Appl· June 2016

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Rainbow trout in seasonal environments: phenotypic trade-offs across a gradient in winter duration.
Ellen V Lea, Jonathan A Mee, John R Post, Sean M Rogers, Stephanie Mogensen

Ecol Evol· November 2015

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Energy allocation strategy modifies growth-survival trade-offs in juvenile fish across ecological and environmental gradients.
Stephanie Mogensen, John R Post

Oecologia· April 2012

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