Publications by authors named "John R Butler"

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AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers.
Brian Belmontes, Katherine K Slemmons, Chun Su, Siyuan Liu, Antonia N Policheni, John R Butler

Cancer Discov· January 2025

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Discovery of pyridyl urea sulfonamide inhibitors of Na1.7.
John R Butler, Gwenaella Rescourio, Benjamin C Milgram, Robert S Foti, Thomas Kornecook

Bioorg Med Chem Lett· October 2022

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Enantioselective Synthesis of (-)-10-Hydroxyacutuminine.
Denise C Grünenfelder, Raul Navarro, Haoxuan Wang, Nicholas J Fastuca, John R Butler

Angew Chem Int Ed Engl· April 2022

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Sulfonamides as Selective Na1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity.
Russell F Graceffa, Alessandro A Boezio, Jessica Able, Steven Altmann, Loren M Berry, John R Butler

J Med Chem· July 2017

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Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives.
Janjira Rujirawanich, Soyeon Kim, Ai-Jun Ma, John R Butler, Yizhong Wang

J Am Chem Soc· August 2016

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Dehydrogenative coupling to enable the enantioselective total synthesis of (-)-simaomicin α.
Yizhong Wang, Chao Wang, John R Butler, Joseph M Ready

Angew Chem Int Ed Engl· October 2013

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Enantioselective total synthesis of (-)-kibdelone C.
John R Butler, Chao Wang, Jianwei Bian, Joseph M Ready

J Am Chem Soc· July 2011

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Transgender DeKalb: observations of an advocacy campaign.
John R Butler

J Homosex· March 2004

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Studying the roles of W86, E202, and Y337 in binding of acetylcholine to acetylcholinesterase using a combined molecular dynamics and multiple docking approach.
Jeremy Kua, Yingkai Zhang, Angelique C Eslami, John R Butler, J Andrew McCammon

Protein Sci· December 2003

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