Publications by authors named "John R Carson"

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The discovery and preclinical pharmacology of JNJ-10450232 (NTM-006), a centrally penetrant, non-opioid structural analog of acetaminophen with comparable analgesic and anti-pyretic properties but no evidence of hepatotoxicity.
Christopher M Flores, John R Carson, Ellen E Codd, Scott L Dax, Edwin K Kuffner

Regul Toxicol Pharmacol· April 2025

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Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.
Ellen E Codd, Judith Baker, Michael R Brandt, Stewart Bryant, Chaozhong Cai, John R Carson

Toxicol Sci· October 2010

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JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence.
Ellen E Codd, John R Carson, Raymond W Colburn, Dennis J Stone, Christopher R Van Besien

J Pharmacol Exp Ther· April 2009

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Parallel methods for the preparation and SAR exploration of N-ethyl-4-[(8-alkyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)-aryl-methyl]-benzamides, powerful mu and delta opioid agonists.
Steven J Coats, Mark J Schulz, John R Carson, Ellen E Codd, Dennis J Hlasta

Bioorg Med Chem Lett· November 2004

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N,N-dialkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, potent, selective delta opioid agonists.
John R Carson, Steven J Coats, Ellen E Codd, Scott L Dax, Jung Lee

Bioorg Med Chem Lett· May 2004

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N-alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, micro and delta opioid agonists: a micro address.
John R Carson, Steven J Coats, Ellen E Codd, Scott L Dax, Jung Lee

Bioorg Med Chem Lett· May 2004

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Synthesis and structure--activity relationships of aroylpyrrole alkylamide bradykinin (B2) antagonists.
Mark A Youngman, John R Carson, Jung S Lee, Scott L Dax, Sui-Po Zhang

Bioorg Med Chem Lett· April 2003

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